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The Cardiovascular Protection of Celery Seed Extract
Date:
September 27, 2022 04:20 PM
You may not think of celery as being particularly special, but this innocuous looking vegetable actually packs a powerful punch. Celery seed extract is loaded with bioactive compounds that offer a wide range of health benefits, including supporting vascular health.* Lets take a closer look at celery seed extract and all the ways it can support your health. Celery Seed Extract and Vascular Health One of the most well-known benefits of celery seed extract is its support for vascular health.* This is thanks to the presence of phthalides in celery seed extract, which help to relax the smooth muscles in your blood vessels.* This relaxation of the smooth muscles increases blood flow and lowers blood pressure.* Additionally, phthalides also help to increase levels of antioxidant enzymes in the body, which further helps to protect vascular health.* Horse chestnut seed extract has also been shown to support healthy vascular function.* Hawthorn extract is another ingredient in this formula that has been traditionally used to support cardiovascular health.* Hawthorn extract works by helping to increase blood flow and strengthen heart muscle contractions.* It's also rich in antioxidants, making it an ideal addition to a formulation designed to support healthy vascular function.* Celery Seed Extract and Brain Health In addition to its effects on the cardiovascular system, celery seed extract has also been shown to offer neuroprotective effects.* This is due in part to the 3-n-butylphthalide (3nB) content of celery seed extract, which has been shown to help protect neurons from damage.* 3nB is also known to increase levels of certain neurotransmitters in the brain, which can help to improve cognitive function.* In Summary: Celery seed extract is a powerful natural compound that offers a wide array of health benefits. From supporting healthy vascular function to protecting brain cells, celery seed extract is an incredibly versatile compound that can benefit many different systems in the body. If you're looking for a natural way to support your health, consider adding a supplement containing celery seed extract to your daily routine.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6467) Curcumin Absorption: How CuraMed Beats Other Supplements
Date:
August 11, 2022 11:15 AM
If you're looking for a curcumin supplement that is highly absorbable by the body, look no further than CuraMed. With its patented BCM-95 turmeric essential oil process, CuraMed beats other supplements on the market when it comes to absorption. In fact, studies have shown that CuraMed is up to 10 times more absorbable than regular curcumin supplements! So if you're looking to get the most out of your curcumin supplement, make sure to choose CuraMed. What is Curcumin and what are its benefits? Curcumin is a yellow compound that is found in the spice turmeric. It has been used for centuries in Asian cuisine and traditional medicine. Curcumin has many potential health benefits, including reducing inflammation, boosting brain function, and fighting cancer. The anti-inflammatory effects of curcumin have been studied extensively. Curcumin is known to block inflammatory molecules, which can play a role in conditions like arthritis, heart disease, and Alzheimer's disease. The brain-boosting effects of curcumin are also well-documented. Curcumin has been shown to improve memory and increase levels of BDNF, a protein that helps to protect brain cells. Additionally, the potent antioxidant properties of curcumin may help to protect against the development of cancer. Although more research is needed, the potential health benefits of curcumin are very promising. How is CuraMed different from other curcumin supplements? CuraMed is a unique curcumin supplement that uses the patented BCM-95 process of manufacturing. This process increases the absorption of curcumin significantly and the turmeric essential oils extends the time at which the curcumin stays in the blood stream, making it more effective and longer lasting than other supplements on the market. In addition, CuraMed does not contain black pepper, which can cause stomach upset in some people. as a result, CuraMed is a more gentle and effective option for those looking to improve their health with curcumin. One can add bioperine which is standardized black pepper to increase absorption further. How does the BCM-95 turmeric essential oil process increase absorbability? BCM-95 is a patented process that significantly increases the absorption of curcumin, the active ingredient in turmeric. Curcumin is notoriously difficult to absorb, so this process is a major breakthrough. BCM-95 uses the essential oils from the turmeric plant, which further increase absorption. This unique process results in a product that is absorbed up to 10 times better than standard curcumin supplements. In addition, BCM-95 maintains blood levels for up to 8 hours, while standard supplements only last for 2-3 hours. This makes BCM-95 the most effective turmeric supplement on the market today. If you're looking for a turmeric supplement that will give you maximum benefit, look for one that contains BCM-95. Key Points:
In summary: CuraMed is a highly absorbable curcumin supplement that uses the patented BCM-95 process to increase absorption by up to 10 times. This patented curcumin BCM-95 formula also help to maintain blood levels of curcumin for up to 8 hours, making it the most effective turmeric supplement on the market today. If you're looking for a way to improve your health with curcumin, CuraMed is definitely worth considering.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6426) The Amazing Ayurvedic Adaptogen Ashwagandha
Date:
October 01, 2020 02:49 PM
Adaptogenic herbs are special! They can help the body with stress, boost immunity, and promote fast recovery from exercise, to mention a few benefits. One of the world's most effective adaptogen is ashwagandha. This ayurvedic herb can:
Daily Energy is from Thyroid support Ashwagandha helps the body feel more energized through normalized thyroid activity. This herb can boost thyroid hormones T3 and T4 by normalizing the thyroid stimulation hormone (TSH) in as little as 8 weeks. Bolster Stamina and Endurance Keeping fit means getting as much out of a workout as one can. Ashwagandha can improve the performance in any workout setting. Cyclists in an 8 week study showed there maximum aerobic capacity the rate at which oxygen is taken up by red blood cells, and respiratory exchange, how much oxygen can be inhaled and carbon dioxide is exhaled. Cyclists found improvement compared to the placebo group studied. Focus, sharpness, concentration, protect your mind Adaptogens can help the body adapt to stress, improve energy, and assist the brain in staying more mentally focused. Ashwagandha can protect brain cells even when sleep deprived. It also increases glutathione levels a key antioxidant needed by the liver. One study showed that ashwagandha can slow the decline of memory and mental function in elderly people. An 8 week study showed that this herb can improve working memory and reaction time. Looking to Improve Memory, Stamina, Endurance, concentration, and energy, give ashwagandha a try for 8 weeks and see the difference.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6366) Omega-3s can improve blood flow in the brain and prevent aging,according to international study
Date:
April 23, 2019 03:23 PM
The inflammation of brain cells, often associated with a decrease in blood flow, can result in several troublesome cognitive symptoms such as not being able to retain memories. Omega-3s actually have the ability to protect cells against related damage, making them highly beneficial in sustaining optimal cognitive function. Not only can it help with brain health, but omega-3s also improve heart health by reducing triglyceride levels while regulating blood pressure. Both of these help contribute to a reduction in heart disease risk. Key Takeaways:
"A study published in the journal Nutrients showed how omega-3 supplementation is beneficial for memory decline caused by aging." Read more: https://www.naturalnews.com/2019-02-28-omega-3s-can-improve-blood-flow-in-the-brain-and-prevent-aging-according-to-international-study.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6165) Herbal supplement gingko biloba found to prevent cell death in thebrain, improve recovery from stroke
Date:
March 19, 2019 02:48 PM
Dr. Yun Xu is the head of the neurological department at Nanjing University, and he has made a breakthrough in the data supporting the herb ginkgo biloba and its neurological advantages to those who have suffered from ischemic strokes. By pairing ginkgo biloba with regular doses of Aspirin, Dr. Xu was able to measure the levels of cognitive ability among a large group of patients dealing with post-stroke difficulties. The results showed that those who had ginkgo biloba administered with their dose had improved memory function, attention, language, and more. Key Takeaways:
"Ginkgo biloba is one of the oldest living species of a tree native to China. It is known to have been used in traditional medicine and as a source of food. The leaves and the nuts of the tree have a high nutrient content, and is best known for its positive effects on the brain and nervous system." Read more: https://www.naturalnews.com/2019-01-03-herbal-supplement-gingko-biloba-found-to-prevent-cell-death-in-the-brain.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6082) Study: PQQ (pyrroloquinoline quinone) may prevent and even reverseAlzheimer's
Date:
January 04, 2019 08:12 AM
Pyrroloquinoline quinone (PPQ) is a microbe that is derived from plants, and it is showing to have neurological benefits that are associated with the prevention of Alzheimer's progression. This particular microbe is able to reduce inflammation in the brain, which can lead to several neurological conditions. It also helps patients in post-stroke recovery because it is able to reduce the area of the brain that is impacted by stroke activity. Most importantly, it helps in the prevention of Alzheimer's due to how it can neutralize levels of oxidative stress. Key Takeaways:
"Glutamate is an important chemical in the brain, but too much of it results in excitotoxicity, a risk factor in both stroke and neurodegenerative disease. PQQ protects the brain from overstimulation by glutamate and the resulting death of brain cells." Read more: https://www.naturalnews.com/2018-12-15-ppq-can-prevent-alzheimers.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5928) Fermented turmeric prevents memory loss caused by oxidative stress and inflammation
Date:
July 16, 2018 09:54 AM
Even without Alzheimer's or dementia, the human brain is apt to experience memory loss over time. Neural cells can die, victims of disease, or inflammation. Simple oxidative stress can be at the bottom of significant loss of cognition. Study has shown that by boosting a key neurotransmitter, a significant amount of natural damage can be avoided. One specific ingredient with the potential to make this happen has been tested on rodents. Rodents were injected with an amnesia-creating medication. A percentage of them also received a dose of fermented turmeric, renowned for its anti-inflammatory activity. The mice given the turmeric were proven to be protected against the affects of the amnesia-producing drug. Key Takeaways:
"Turmeric contains curcumunoids like curcumin, a well-known antioxidant and anti-inflammatory compound that shields neurons from damage." Read more: https://www.naturalnews.com/2018-07-11-fermented-turmeric-prevents-memory-loss-caused-by-oxidative-stress-and-inflammation.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5668) Scientists study the neuroprotective effects of fermented Curcuma longa L. (turmeric)
Date:
July 04, 2018 05:54 PM
A recent Kristina University study suggests that fermented turmeric may help protect brain cells from being degraded by inflammation and oxidative stress. The same researchers found that fermented turmeric may also help protect against the impact of the amnesiac compound scopolamine. Researchers subjected scopolamine-treated mice to mazes and inflicted oxidative stress on rat brain cells to test whether fermented turmeric offered any protection. Preliminary results suggest that fermented turmeric could have value as an alternative or complementary treatment for neurodegenerative diseases symptoms. Key Takeaways:
"It could serve as an alternative or complementary therapy for age-induced neurodegenerative diseases like Alzheimer’s disease." Read more: https://www.naturalnews.com/2018-07-02-scientists-study-neuroprotective-effects-of-fermented-curcuma-longa-turmeric.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5655) Treating Autism With Cannabis Now Has Scientific Support
Date:
October 20, 2017 10:14 AM
Autism is a hard thing to diagnose and treat. There are different forms of it. There are also different levels of severity. Cannabis is one way some treat it even though it is controversial. Most cannabis uses are. There is scientific evidence that this may work. It is at least looking into if you can get past the stigma, though it might not work for everyone. Some don't react to it just like any other medication. Key Takeaways:
"Looking at the quality of the social interactions, we found that our autistic-like mice tended to dart away from a social interaction and huddle in the corner of their testing box." Read more: https://www.civilized.life/articles/cannabidiol-treatment-for-autism-scientific-support/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5352) 10 Reasons You should Be Taking curamed daily!
Date:
September 05, 2017 12:21 PM
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5225) Olive Oil Can Help Preserve Memory And Prevent Alzheimer's
Date:
June 24, 2017 12:14 PM
Alzheimer's disease affects nearly 44 million people worldwide. According to a study done by researchers at Temple University in Pennsylvania, olive oil can help preserve memory and essentially prevent Alzheimer's disease. Dominico Pratico, lead researcher of the study, stated that olive oil helps reduce inflammation and activates a process in the brain called autophagy. Autophagy is a way that the cells in the body break down and clean out unwanted debris in the body. Mice were given olive oil in the study, and the mice that received the olive oil showed signs that the olive oil made their memory improve and lessened the signs of Alzheimer's. The researchers from this study plan to continue researching the effects of olive oil and Alzheimer's in older mice to see if they can eradicate the disease in mice altogether. Key Takeaways:
"When the team studied the brain tissue from both groups of mice, they noticed "dramatic" differences in nerve cell appearance and function. As compared to the mice that didn't consume the oil, the brain cells of rodents in the oil group showed a dramatic increase in nerve cell autophagy activation." Read more: http://doctor.ndtv.com/news/olive-oil-can-now-help-preserve-memory-and-prevent-alzheimers-1715610
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4877) CBD and Your Brain
Date:
June 14, 2017 12:14 PM
CBD is found in cannabis sativa otherwise known as marijuana and is useful in treating many neurological disorders such as depression, anxiety and even epilepsy. Unlike THC, CBD has no psychoactive effects. CBD has been found to protect brain cells from harm in neurodegenerative diseases like Alzheimer's. Best of all CBD has literally zero side effects! Research shows that CBD has opened many doors leading to a cure for depression and anxiety. CBD has been proven to reduce swelling, pain and inflammation caused by injury and arthritis even when applied topically. CBD may not be a medical cure all but it has been proven to be a very useful tool in the treatment of many medical conditions. Key Takeaways:
"When various brain injuries from animal models were examined, it was found out that CBD boosted a number of viable brain cells." Read more: https://www.cashinbis.com/cbd-and-your-brain/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4831) Phostphatidylyserine: Promotes Long Term Brain Health
Date:
June 13, 2017 11:14 AM
Phostphatidylyserine promotes long term brain health in people. It is a fatty compound heavily involved in the health of the cellular membranes. It keeps your brain cells healthy as you age. There are many benefits to it. It helps to lower stress as well. It can also help to boost your learning speed. It actually does this at an impressive rate. It is a really amazing thing and it can help out many people in the world. Read more: Phostphatidylyserine: Promotes Long Term Brain Health
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4824) Marijuana for your memory? Study suggests wonder drug can reverse memory loss in older people
Date:
May 29, 2017 09:14 AM
Marijuana has been a hot topic for many years, but nothing like it is today. For years, people believed it caused addiction, destroyed brain cells, and many other nefarious results. Yet today, with legalization of this drug becoming ever more popular, many studies are looking into its efficacy for MS, pain, inflammation, anxiety and depression. A recent study indicated it might even help with the memories of elders. In Time we will learn its many benefits, but at the present, its used most for pain. Key Takeaways:
"The findings showed that marijuana clearly had a positive effect on mature and aging brains, though it has yet to be studied further in humans." Read more: http://www.naturalnews.com/2017-05-15-marijuana-for-your-memory-study-suggests-wonder-drug-can-reverse-memory-loss.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4721) 5 health benefits of taking cannabis
Date:
May 25, 2017 12:14 PM
Though a sensitive topic, science suggests that health benefits of taking cannabis can and should be considered. Some of the benefits of doing so include slowing the development of cancer cells, treating epilepsy, growing brain cells and helping those suffering from Alzheimer's. The reason for this is simple: our bodies are tailor-made to accept and help cannabinoids thrive in the body. Though not everyone reacts to cannabis in the same manner, it can't be ignored that this potent material does harbor benefits to those that engage in it. Key Takeaways:
"Cannabis is now prescribed as an alternative medicine for the treatment of epilepsy." Read more: http://www.trainingzone.co.uk/community/blogs/vivek-gururani/5-health-benefits-of-taking-cannabis
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4692) Research Proving Cannabis Kills Cancer Cells Safely has been Suppressed Since 1974
Date:
March 15, 2017 08:59 AM
In 1974 the NIH working with the DEA sponsored research to prove that cannabis caused destruction of brain cells and suppresses the immune system. The research was cancelled and documents were destroyed when it was found it actually enhanced the immune system as well as destroyed cancer cells. Studies are now being sponsored overseas with promising results. Cannabis, when vapors instead of smoked kills cancer cells and city's off blood supply to the cells. There us even a case if a baby cured if brain cancer without surgery or radiation. Standard oncology treatments kill healthy cells as well as cancer while cannabis kills only cancer cells. The research should be allowed in the US with federal funding. Key Takeaways:
"After several attempts to get cannabis oil allowed through the court system with many testimonials from those who had been helped, Rick realized this important harsh reality: The cancer industry does not want a cure for cancer." Reference: //www.healthnutnews.com/research-proving-cannabis-kills-cancer-cells-safely-suppressed-since-1974/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=4156) Scientists discover new mechanism of how brain networks form
Date:
January 15, 2017 12:59 PM
As long as neurological disorders have been diagnosed, scientists have tried to determine how the brain works in order to better treat them. One thing we do know about the brain is that it creates maps of experiences that help us learn. As we learn, these maps are altered to adapt to our surroundings. Excitatory neurons in the brain have been found to narrow their scope upon learning new information. Inhibitory neurons, conversely, have recently been found to get broader when learning. This new understanding of neurons will go far in efforts to repair brain tissue. Key Takeaways:
"Scientists have discovered that networks of inhibitory brain cells or neurons develop through a mechanism opposite to the one followed by excitatory networks." Reference: https://www.sciencedaily.com/releases/2016/12/161226211235.htm
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3786) Vitamins A and C help erase cell memory - Knowridge Science Report
Date:
December 09, 2016 07:59 AM
Vitamins A and C aren't just good for your health, they affect your DNA too. Researchers at the Babraham Institute and their international collaborators have discovered how vitamins A and C act to modify the epigenetic 'memory' held by cells; insight which is significant for regenerative medicine and our ability to reprogramme cells from one identity to another. Key Takeaways:
"Vitamins A and C aren’t just good for your health, they affect your DNA too." Reference: https://knowridge.com/2016/11/vitamins-a-and-c-help-erase-cell-memory/
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3603) Six reasons why walking is the best medicine for mental health
Date:
November 13, 2016 10:04 AM
Did you know walking can help you work better, help with addiction, make you happy and keep you young? Walking can make you more creative and give your confidence a boost in addition to creating new brain cells that can help with decision-making and learning. By releasing endorphins, walking can also make you feel happier and it can also help control addiction by increasing dopamine. Walking can even help you age by sharpening memory and by preventing cognitive decline. Key Takeaways:
"A lot of people take up walking in hopes of getting fit or losing a little bit of weight, but many people find that it becomes a surprisingly enjoyable habit once they get started." Reference: //www.naturalnews.com/055913_walking_mental_health_depression.html
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3436) MSG: Here is why you should stay far away from it.
Date:
September 20, 2016 03:15 PM
MSG is a neurotransmitter that stimulates nerves, which makes food that would normally be bland taste great. Because MSG is often used to compensate for low-sodium or low-fat contents, many food manufacturers try to downplay its toxicity in order to promote their products as healthy. As a result, people who believe they are buying healthy foods are actually putting their health at risk by consuming large amounts of MSG.
The following are the health risks of MSG:
MSG is widely used in the food industry, which makes finding MSG-free foods a challenge. It is often hidden on ingredient lists under different names to mislead consumers.
If you are experiencing inflammation issues, take Curcumin to eliminate all forms of inflammation.
Reference: //www.mayoclinic.org
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3301) Ashwagandha - Herbal Way to Reduce Stress
Date:
September 07, 2015 06:53 AM
Mankind has tried every possible way to overcome the issue of stress. Among these, the natural and healthy ones include family get-togethers, yoga, meditations, or rituals. Others might show the same unwanted result on your body which includes, consumption of drugs, think cocktails, or midnight ice cream bings. Ashwagandha has a special name and place in ayurvedic arrangement of medicine as it is a successful herb for reducing stress. It is an herb utilized since ancient times that assistance to cool your mind and keep you free from stress and anxiety. Ashwagandha is a natural way to lessen stress. In today's fast moving life you may get a disease-free life by taking ashwagandha everyday. It will give you mental peace and will also enhance your working capacity. Ashwagandha serves to decrease stress as well as make your body disease-free. Ashwagandha has a property to decrease negative contemplations from your mind and deadheads in inspirational attitude. It gives you a new way of dealing with stress naturally. It supports your vitality and makes you solid from inside to face any more regrettable situation.
It feeds the weak cells in your body and help to give a superior performance. Ashwagandha brings peace in your life by balancing powers that act on mind, body and soul. Regular intake of this herbal stress reliever will give you great results within couple of days and you will start feeling better and see changes in the effectiveness of your work. Ashwagandha has a special property that relieves the mind and gives you a sound rest. Adequate rest is an important factor to diminish stress. Ashwagandha serves to induce natural rest. Many chemical medicines are available in the market that create a great deal of reactions and regular intake of such medicines make you habitual. You get to be subject to the medication and it delivers adverse impacts on different organs of the body. A herbal supplement, for example, ashwagandha is a natural answer for ease stress. It is totally safe and does not create any adverse impacts. A man under stress turns out to be aloof and may attempt to confer suicide. Ashwagandha serves to take away such contemplations from mind by nourishing the brain cells. It also gives sustenance to other body cells and supports up your vitality level to deal with any situation naturally. Ashwagandha is also useful in treating gloom and anxiety. It cultivates positive considerations in mind and makes you feel happy in each situation. It revitalizes your body cells and tissues to give you more vitality. It increases dopamine levels that assists in dealing with stress. Ashwagandha also serves to enhance memory skills. Ashwagandha is a complete tonic for your brain and sensory system and does not cause any adverse reactions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3212) Benefits of Boswellic Acid To The Body
Date:
April 20, 2014 08:25 PM
Benefits of boswellia Rarely do people bank on herbs for treatment. Chemically manufacture medicines have taken over. However, what makes Boswellia herb very important? This herb has been used for a very long time. It is extracted from the Boswellia serrate tree. This herb is popular among other pharmacological medicines because of its medicinal values of reducing the effect of inflammation and inflammation related diseases. What is inflammation? Our body goes through very complex biological processes to keep us healthy. Inflammation is one of them. Inflammation has been the response action that the body takes towards an intruder. The body does this by producing prostaglandins and leukotriene; they are otherwise called inflammation mediators. Most of the time, the intruder can be harmful stimuli or pathogens and damaged cells. The body responds by causing acute pain in places like toes and fingers. Besides the pain, heat, swelling, redness and loss of function are signs of inflammation. Note that inflammation is not an infection. Examples of inflammatory disease Examples of inflammatory diseases are bronchial asthma that leads to narrowing of the respiratory tract and makes breathing difficult. Diabetes, type 1 is an inflammatory disease that is caused by the inflammatory mediators. They eat up the pancreas until it is exhausted. Production of insulin to counter diabetes will be affected largely. How boswellia works Boswellia releases boswellic acid. This is the main ingredient that is used to fight and heal inflammation. It does this by suppressing the release of prostaglandins and leukotriene. Bowellic acid comes in many forms. Acetyl-11-keto-B is one example that when released, inhibits the synthesis of enzymes that will produce leukotriene hence lead to inflammation. Constant use of this herb heals and prevents the body from inflammation diseases. Besides healing inflammation diseases, boswellia reduces the effects of brain cells tumor and colon cancer. The herb can be used to activate tumor suppression genes, a genes that will control and eventually reduce the growth of cancer cells. Sources
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3100) Can Rhodhiola Help Improve Mood?
Date:
April 10, 2014 12:15 AM
Health benefits of rhodiola Rhodiola, renowned for amazing health benefits is a safe herb that can increase the energy level of body. It is one of the best-used herbs for the treatment in wide range of health issues like fatigue. Stress, a main cause of many nervous disorders can be easily cured with the help of rhodiola. It relaxes nerve cells and improves blood flow in body. This function of rhodiola can prevent a wide range of health issues like depression, stress and anxiety. Today, rhodiola is one of the top recommended herbal cures to improve mood level. As per research, fatigue is found to be as a common health issue in today's busy life. Uncontrolled fatigue may negatively influence the daily life activities of person. This condition can be minimized by including rhodiola in daily diet. It stimulates blood circulation in body and minimizes the risk of health issues. Low immunity health is a main cause of many health problems. How to boost our immunity health naturally? This is a common question heard from people. Today, there are many herbal products available online to improve our immunity health. Rhodiola extract is one of the best-used herbs to improve the immunity health of body. Boosting up the functioning of brain cell is a highlighting function of rhodiola extract. It stimulates the blood flow in brain and enhances your memory capacity. Reducing body weight is another main advantage of using rhodiola extract. Uncontrolled obesity can lead way to several health issues in life like heart failure and stroke. This condition can be minimized by including rhodiola extract in daily diet. Today, rhodiola is one among the key ingredients used for the preparation of products that can enhance your energy level and mood level. If you are in search of a safe herbal remedy to improve mood level, then never hesitate to include rhodiola extract in daily diet.
Sources
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=3088) Health Benefits Of Taking L-Carnitine
Date:
November 04, 2013 07:18 PM
What is L –Carnitine L –Carnitine is an amino acid that is naturally produced in the body. It is found in two different amino acids; methionine and lysine. Dietary sources of this amino acid include pork, beef and small amounts of milk, chicken and fish. This amino acid is highly required by the body and the following are the health benefits of Carnitine. Important in the management of heart conditions Carnitine is important in the management of a number of heart related conditions for example congestive heart failure, diphtheria, chronic chest pain, heart attack and high cholesterol. Studies show that Carnitine indeed is helpful in dealing with a number of heart related diseases. Boosts overall brain function A recent study shows that Carnitine aids in the recovery of stroke among animals. This clearly shows that this amino acid targets the brain cells. It contains nutrients that are highly required by the brain to function properly for example vitamins E, B-12 alpha-lipoic acid and folic acid. Helps in burning body fat Carnitine is a portent fat burner. It is needed in the transportation of fat into cells which will be used for the production of energy in the body. When the Carnitine levels are increased in the body, the body increases the fat burning process and then boosts energy levels in the body. Prevents diabetes This amino acid can prevent diabetes and promotes cardio vascular health. With its antioxidant properties Carnitine eliminates free radicals and also reduces oxidative stress. This is very important in the improvement of your insulin health and also help in fat loss. Improves male fertility Studies show that adequate Carnitine levels in the body are necessary for male fertility. According to the study fertile males had adequate levels of this amino acid it was associated with healthier sperm. While the others who were considered infertile had compromised sperm health and lower Carnitine levels.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2876) Coconut Oil for Memory Enhancement
Date:
December 27, 2012 12:53 PM
Coconut oil has been widely used for centuries for various purposes. Mainly, it is a cooking ingredient, used for frying and for adding flavor to meals. Aside from this, many nations have different ways of using it as treatment for various illnesses. Countries like Jamaica, Panama, and India believe that ingesting the oil helps prevent contracting any disease and helps in the speedy recovery when sick. Topical Uses: People from the Philippines and Thailand use the oil for massaging to provide relief from painful muscles and joints. Other topical uses are for moisturizing of the skin and for the healthy growth of hair. Since 2008, new studies have been conducted to test the effects of coconut oil in enhancing the memory and to cure Alzheimer's disease. MCT (Medium Chain Triglycerides) Benefit: The most astounding find is the presence of MCT or medium chain triglycerides in coconut oil in high concentration. This MCT creates a string of processes that ultimately helps in curing neurodegenerative diseases. MCT against Amyloid-Beta
Amyloid-beta is a protein that forms into plaques in the brains. They decrease the efficient functioning of the nerve cells that then causes the decline in memory. Most drugs prescribed to Alzheimer patients target these plaques, to dissolve them and consequently see an improvement. Studies done on dogs by incorporating MCT in their diets showed that the levels of amyloid-beta has declined, which is a very positive effect. Likewise, energy levels in the brain have gone up among the test subjects. MCT to Promote Ketone One cause of Alzheimer's disease is the inability of the brain to metabolize glucose and transform it to energy. As you all know, glucose is the main energy source of the body that provides it the energy it needs to function. This glucose comes from the carbohydrate that comes from food sources. Without this fuel, the brain cells could degenerate. Fortunately, glucose is not the only source of energy for the brain. It can also come from ketones, which are produced from fats in the liver. However, the liver does not continually produce this. The human body, being smart as it is, only produces ketones when the glucose level drops in order to compensate for the loss of energy source. This is why people who have cognitive disorders often go on a fat and protein diet to trigger the production of ketones, by lowering their intake of carbohydrates. Still, maintaining such a diet for long periods is hard. The good thing is studies have shown that ingesting MCT has increased the level of ketones in the body, regardless of the amount of glucose present in the system. It is believed that MCT is converted to ketone, thus, providing the brain the energy it needs. MCT and Omega-3 Fatty Acids Another study done on dogs showed an increased level of omega-3 fatty acids in their brain. Omega-3 fatty acids have many benefits to the body, including improvement of brain function. They support the effective transmission of energy from one neuron to another through the synapses. This consequently makes learning easier, promotes faster reactions, and heightens memory. Unfortunately, this fatty acid is not produced in the body and people have to rely on food sources, such as fish and nuts. Studies have shown that MCT from coconut oil induces the production of omega-3 from fats that are already present in the body.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2781) Health Benefits of Alpha Lipoic Acid
Date:
July 02, 2012 07:53 AM
Alpha Lipoic Acid Alpha Lipoic Acid, popularly abbreviated as ALA, can also be referred to as thioctic acid. It is an antioxidant as well as a fatty acid occurring naturally in the body. Every single cell in your body has this compound, which can also be sourced from food staff such as broccoli, spinach, organ meats, peas, brussel sprouts and rice bran. The following is a comprehensive list of the health benefits of ALA. Health benefits of ALA on the aging process ALA is known to delay the aging process. It does this through its antioxidant properties that help reduce cell damage, a condition that contributes to early aging of cells. This function also helps protect you from chronic illnesses that are attributed to old age. Health benefits of ALA on brain cells ALA also protects your brain from the damage caused by free radicals, thus protecting you from dementia and memory related problems. Studies conducted on animals have shown that this acid helps boost memory. Free radicals are also associated with brain cancer, and so this antioxidant helps protect you from developing malignant tumors in your brain. It also protects you from diseases such as Alzheimer. Health benefits of ALA on blood sugar Lipoic acid has been found to help regulate blood sugar thus helping relieve the symptoms of diabetes. It helps relieve the numbness, tingling, pain and itchiness experienced by diabetes patients. This function makes ALA an effective remedy for diabetes-related conditions such as peripheral neuropathy, cardiac autonomic neuropathy and autonomic neuropathy. Health benefits of ALA on the skin ALA has been used to manufacture a wide range of beauty creams because of its ability to improve the skin texture. This acid also protects the skin against sun damage, thus reducing chances of developing sunburns. It reduces the size of your skin pores thus helping correct specific types of acne. Finally, ALA helps improve the radiance of your skin thus giving you a beautiful and glowing skin. Other health benefits of ALA ALA plays almost all the roles of antioxidants, since it also helps boost your immunity. This function helps protect you from diseases such as:
• Multiple sclerosis One of the advantages that ALA has over other antioxidants is that it is both water soluble and fat soluble, unlike the other antioxidants that are soluble in either water or fat only. Therefore, its health benefits can be felt all over your body. In addition, ALA is found in all cells within your body and so deficiencies are rare. Even though ALA is synthesized naturally within your body cells, their production goes down as you age. This is why alpha lipoic acid supplements are available. They are often presented in the form of capsules. There is no recommended daily dose of this supplement, but you need the guidance of a health physician in order to determine the right dosage for you. These supplements may cause serious reactions with specific drugs, and so your doctor will determine whether they are appropriate for you. Children are not allowed to take alpha llipoic acid supplements because their bodies are still in a position to release enough for their needs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2662) How Does Phosphatidyl Serine Improve Your Health?
Date:
April 17, 2012 07:22 AM
Health Benefits Of Phosphatidyl Serine Phosphatidyl serine is phospholipid that is vital to your brain functioning. The phospholipid are molecules containing both fatty acids and amino acids found in every cell in the body. Phodphatidyl Serine supplements are plant extracts that has been proven safe and effective therapeutic substance in remedying memory disorders as well as in enhancing higher brain functions. Clinical trials have shown that this vitamin supplement do strengthen your memory, increase mental acuity, increase concentration, boosts learning, enhances attention and vigilance. In addition, Phodphatidyl serine relieves depression while improving your mood and inhibits increases in cortisol induced by exercise and stress. The supplement works by enabling your brain cells to metabolize glucose and releases it to bind with neurotransmitters which hence support learning, memory and other cognitive functions. Phodphatidyl serine enhances the cells communication in the brain through increasing the number of membrane receptor sites. It is also important to note that this natural supplement modulates the fluidity of the cell membranes which are essential in supporting the ability of brain cells to send and receive chemical communications. Health Benefits Another health benefit associated with Phodphatidyl serine is its ability to restore the supply and output of acetylcholine in the brain. Acetylcholine is an essential transmitter to memory and is associated in reversing aging. Further, it increases the availability of endogenous chlorine used for de novo synthesis and production. Patients diagnosed with clinical depression that have ben put under the treatment of Phodphatidyl serine have registered a remarkable improvement with their symptoms. This follows from the fact that the supplement stimulates the production of dopamine by the brain. A deficit in dopamine in the brain has also been associated with attention deficit disorder and hence the natural supplement of Phodphatidyl serine has demonstrated to be an effective remedy for the disorder. Weight Training Research indicates that athletes involved in weight training, endurance running and cycling can reduce muscle soreness when they use Phodphatidyl serine. The athletes on this supplement have also been reported to undergo speed recovery during their rigorous training sessions. Other benefits of the supplement include; testicular function, formation of bone matrix, heart beat coordination, cell repair and removal by the immune system and secretion of hormones by the adrenal glands. Stress It is vital to note that phodphatidyl serine is present in almost every cell in our body and the membrane proteins it activates are important in all these cells. However, our bodies cannot produce enough amounts of it when under stress, when there is a deficit in necessary enzymes and metabolic cofactors, and when aged. Stress increases the demands for phospatidylserine thus depleting the available levels in the cells. On the other hand, aging not only increases the brain's requirement for phosphatidylserine but also leads to inefficiency in the digestive and metabolic functions of the body. This makes it difficult for aged people to acquire enough of it from the diet and thus it is recommended that aged people should use phosphatidyl serine supplements. Modern diets with low fat and low cholesterol levels have been shown to be lacking in phodphotidyl serine to levels of up to 150 mg per day. A vegetarian diet on the other hand may have a deficit of up to 250 mg per day. This deficit in supply of Phodphatidyl serine in the diet leads to impairment of your brain's ability to form, store, process and even remember. It is vital hence to consider taking vitamin supplements with phosphatidyl serine to cater for the deficit which may be detrimental to your health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2635) How Much Turmeric Should Be Taken For Alzheimer's?
Date:
October 05, 2011 02:08 PM
Turmeric is an herb which is a perennial plant included in the family of gingers. This plant is considered to be rhizomatous and has been found to be abundant in tropical countries such as South Asia. For its cultivation, this plant must grow in a climate with a temperature of 20 to 30 degrees Celsius and ample amount of yearly rain. In these kind of climates, this herb can grow healthy and abundantly. In some countries, an annual collection of rhizomes is done and then reproduced and grown the next season. Turmeric is commonly used as a culinary spice or ingredient. It is dried in extreme temperatures of ovens and ground into a yellow to orange powder. This spice is common in many Asian dishes. Aside from its culinary use, it can also be helpful in maintaining the health of the human body. The known active ingredient of turmeric is Curcumin. This chemical substance has a unique slightly metallic taste and peppery in flavor. It also has a mustard–like aroma. Hence, it is considered to be an important condiment in many Middle Eastern recipes. In addition to Curcumin, turmeric consists of about 5 % of essential oils. With its many health benefits, one of the most interesting is its effect on the brain in helping prevent the onset of Alzheimer’s disease. Clinical studies and surveys reveal that people who consume large quantities of curry have a lesser risk and incidence of having Alzheimer’s disease. Therefore, intensive studies are being conducted to test and prove its safety and effectiveness as a chemical substance which can greatly help in the prevention of the increasing number of Alzheimer’s disease cases. Other factors are also considered such as the individual’s diet, familial history, social and economic status as well as lifestyle. Alzheimer’s disease has been closely related to the increasing damage of brain cells due to oxidation. This brain damage will significantly cause an effect to the person’s memory thus Alzheimer’s disease occur. Curcumin in the turmeric has the potent capacity to prevent this cellular damage thus slowing the development of such disease. Studies have also shown that Curcumin can significantly impede certain mechanisms that are involved in the progress of Alzheimer’s disease. Aside from its benefit in decreasing the risk of Alzheimer’s disease, turmeric also has a potential anti – inflammatory property and can effectively regulate blood cholesterol levels. The recommended dosage of turmeric has not yet been officially established. Therefore, if you are planning to supplement with turmeric, it would be best that you should consult your doctor. The dosage of this supplement varies from person to person in terms of age, weight, other health conditions and status of his/her Alzheimer’s disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2482) Can Vitamin B12 Boost Mental Alertness?
Date:
July 18, 2011 12:01 PM
The body needs various nutrients in order to make vital biological reactions possible. These bodily reactions are necessary for energy production, immune system enhancement and health improvement. These nutrients are classified into two, macro and micronutrients. In addition, these micronutrients are further divided into vitamins and minerals. These vitamins are needed by individuals to help the body grow normally. Vitamins can be supplied by the food we eat. However, the body can make certain vitamins such as vitamin D and K. Individuals who are in strict vegetable diet usually need vitamin B12 supplement. In this article, we will be focusing on Vitamin B 12 or also known as cyanocobalamin. Vitamin B 12 is also a water– soluble vitamin. It is considered as essential because it is not produced by the body. Excellent sources of this vitamin include fish, shellfish, meat, milk and milk products. Vitamin B 12 is also available in supplements in combination with other vitamin B complex. Like the other B vitamins, vitamin B 12 is also necessary in maintaining healthy brain cells and in the normal production of red blood cells. Riboflavin is also a component of DNA which is the cells’ genetic material. Vitamin B 12 in the stomach combines with a substance called intrinsic factor so that it can be absorbed into the blood stream. Vitamin B 12 boosts mental alertness because it facilitates normal formation of body cells most especially the nerve cells. Vitamin B 12 is also an important component of the myelin sheath. Myelin sheath is necessary for the proper functioning of the nerves. Myelin sheath functions by increasing the speed of the movement of the impulse. With the presence of myelin sheath, the impulse hops from one sheath to another instead of just moving continuously along the nerve fiber. This is the reason why vitamin B 12 is commonly employed for boosting mental alertness and concentration. In fact, it is also commonly employed for treatment of memory loss and Alzheimer’s disease. Vitamin B 12 can also help lower the risk of cardiovascular diseases by decreasing the concentration of homocysteine in the blood stream. Studies show that high levels of homocysteine can greatly lead to atherosclerosis which is the narrowing of arterial walls. It can also increase the tendency of abnormal blood clotting thus increasing the risk of clotting – related disorders. These factors can precipitate heart attacks and cerebrovascular accidents or commonly known as stroke. Another function of vitamin B 12 is its involvement with energy metabolism in every cell of the body. Therefore, vitamin B 12 is not only good for enhancing mental alertness but also increasing energy levels. It is also required by the body so that other nutrients from the diet can be absorbed and readily utilized by the cells. Vitamin B 12 is relatively safe. It usually comes in combination with other B vitamins in the form of tablets, capsules, or liquid which can be bought over –the – counter.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2370) Phosphatidyl choline, Aging, And Intelligence What You Must Know
Date:
May 24, 2011 10:52 AM
If you are aging and wish to maintain your intelligence, experts are turning to the belief that a supplement of phosphatidylcholine could enable you to do this. For a long time, lecithin supplements have been recommended to people seeking a way to maintain their faculties as they age, and in a number of cases it appears to have been effective. Now it is phosphatidylcholine that is being recommended, and it is certainly no coincidence that this phospholipid/choline combination constitutes the bulk of lecithin. Nor is it any coincidence that the cell membranes of the brain and everywhere else in your body contains large quantities of phosphatidylcholine, or at least should do for maximum effectiveness. The membranes of the brain cells of a young infant consist of around 90% of this phospholipid, while those of the brain cells of a 60 -70 year old contain only around 10%. This figure will naturally vary with each person, and some individuals could have a considerably higher amount and others less, but that is a rough average. It follows, then, and many experts agree, that by taking a supplement of phosphatidylcholine you can slow down the natural loss of cognitive ability, memory and overall brain function. If taken according to the recommended doses there are no significant side effects, so what do you have to lose? Certainly not your memory and your ability to make that decision because you are going to lose that in any case - unless these experts are correct in their thinking and you take their advice.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2303) What is Vinpocetine and How Does it Help with Memory?
Date:
March 24, 2011 02:18 PM
Vinpocetine And Brain HealthVinpocetine is a derivative of an organic compound found in the plant species Vinca minor, or common periwinkle. It is best known for its neuroprotective effects and used in Europe and Japan in treatment of age-related cognitive decline. More often than not, its activities inside the human body are described as vasodilator, which means it increases blood flow. It has also seen a growing presence in the North American market as a dietary supplement. Vinpocetine is available as a prescription drug in certain European countries and Japan and has shown to be speed up prognosis of patients who suffered cerebrovascular accident, or CVA, which is commonly referred to as stroke. Most cases of cerebrovascular accident are brought on by ischemia, or very poor circulation of blood to certain parts of the brain. This is exactly what vinpocetine is beneficial for, and recommended dosages have so far yielded very encouraging results. Improves Blood Circulation in the Brain It has long been postulated that one of the mechanisms of action of vinpocetine is limiting the effects of Na+ channels that are sensitive to voltage. This creates a neuroprotective effect believed to contribute to mental clarity and sustained attention. Striatal nerve endings produce extracellular Ca+ ions that induce neuronal damage through a phenomenon called excitotocity. High levels of Ca+ ions are now alleged to be correlated with voltage-sensitive Na+ channels. Striatal nerve endings see a decline in Ca+ ions when Na+ channels are influenced by vinpocetine, and in the process lessen excitotoxicity. Attenuates Ischemic Neuronal Damage In addition to limiting neuronal damage induced by excitotoxicity, which in turn results from cerebral ischemia, vinpocetine plays an active role in the upkeep of brain cells after being subjected to ischemic damage. As a vasodilator, it not only counters the effects of ischemia but also significantly increases the brain’s access to bioactive molecules like oxygen and other nutrients exclusively distributed by the circulatory system. It also inhibits the enzyme phosphodiesterase, which is specialized for the breakdown of cyclic adenosine monophosphate, or cAMP, and cyclic guanosine monophosphate, or cGMP. By so doing, vinpocetine contributes to glucose metabolism and energy production in the brain, and at the same time, improves the distribution of bioactive compounds in the central nervous system. Displays Neuroprotective Activities Vinpocetine and its precursor belong to a group of indole alkaloids known as tryptomines, which are present in the human brain and the rest of the central nervous system in minute quantities. These organic compounds make up several psychoactive drugs and in the human body act as neuromodulators and neurotransmitters in the form of melatonin and serotonin. Vinpocetine in particular displays activities that are primarily anti-inflammatory in nature. Several studies point to its effects on the enzyme complex called IkB kinase, which regulates cellular responses to inflammation, by preventing the translocation of a protein complex called responsible for the process of inflammation within cells. In a Nutshell, vinpocetine can help you think clearer and protect the brain from inflammation and free radical damage. Give vinpocetine a try today!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2257) stroke, what is it?
Date:
September 28, 2010 03:05 PM
A stroke occurs when a clot forms inside an artery that blocks the flow of blood to the brain. This is also called a thrombus. Embolism, which is a wandering clot, is carried in the bloodstream until it wedges in one of the arteries that lead to the brain. Aneurysms are blood-filled pouches that balloon out from weak spots in the artery wall and burst. A hemorrhage results when a defective artery in the brain that bursts, flooding the surrounding tissue with blood. A mild attack can lead to temporary confusion and light-headedness, along with difficulty in speaking clearly, weakness on one side of the body, visual dimness and confusion, severe speech difficulties, and/or sudden or gradual loss or blurring of consciousness. Additionally, amnesia can occur, but it is not typically permanent. A coma can even result for short or long periods. It is important to watch for early warnings of stroke. Although they may only last a few moments, early warnings include fainting, stumbling, numbness or paralysis of the fingers of one hand, blurring of vision, seeing bright lights, and loss of speech or memory. It is much wiser and significantly less expensive to start improving health in order to prevent this disease. Some doctors who have treated thousands of people suffering from stroke believe that most strokes can typically be prevented. The Chinese often view strokes as being caused by blood stasis and stagnation of the liver. Chinese medical practitioners attempt to prevent strokes and treat them by treating constipation. Constipation causes a poisoned bloodstream, setting the stage for a possible stroke. Poisoned blood flows through thousands of miles of arteries, veins, and capillaries. The walls of the arteries are made up for cells, which are subject to the same injury from toxins as the cells in the kidneys. The kidneys degenerate at the same time that the arteries do and even from the same causes. When the walls thicken and harden, degeneration results. As they harden they become more brittle, causing them to burst more easily under pressure. Pressure increases as the hole through the arteries grows smaller. AS the walls become more brittle, the extra pressure causes the blood pressure to rupture. This, in turn, causes a stroke. The brain cells rely primarily on oxygen-rich blood in order to get nourishment. If they don’t receive this nourishment, the brain cells will die. Other causes of this are poor diet, lack of exercise, obesity, and smoking. Emotional health is an essential part to any healing. Strokes are often associated with resistance to change, giving up on life, and getting tired of doing all the same things over and over. It is important that we learn to accept changes and are able to go with the flow of life. Life can be exciting. Changes provide us with a new perspective on living. Some herbs and supplements have been used to help as a preventative. These include vitamin E, vitamin C, coenzyme Q10, garlic, evening primrose oil, lecithin, chlorophyll, flaxseed oil, and germanium. For additional information on any of these, please contact a representative from your local health food store.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2188) DHEA and Your Health
Date:
March 16, 2010 12:27 PM
DHEA is a naturally occurring hormone that is produced within the adrenal glands. The most abundant hormone found in the body, it is sometimes referred to as the “mother hormone.” When hormone levels are too low or out of sync, the body is unable to function as intended. DHEA levels reach their peak in the body around age twenty-one. After that, the levels tend to decline over the years. This substance is a precursor hormone that can be metabolized into other adrenal hormones and act with other hormones. When DHEA levels are normal, it aids the immune system in maintaining balance and fighting diseases and infection. This, in turn, protects the body form a variety of serious problems that can occur, including cancer. Although the full extent of DHEA's benefits is not entirely known, there is a great deal of evidence that links low levels of DHEA to conditions such as cancer, Alzheimer's disease, arthritis, osteoporosis, chronic fatigue syndrome, diabetes, fertility problems, lupus, rheumatoid arthritis, multiple sclerosis, allergies, PMS, and even weight problems. Many people even believe that this hormone is the single most important factor in maintaining health. Scientific studies have determined that individuals with cancer seem to have lower levels of DHEA than those individuals who are healthy. It has been found that DHEA has the ability to inhibit one of the most important enzymes that is responsible for the feeding of cancer cells. Research has also concluded that DHEA can help in a variety of types of cancer, including colon, lung, skin, breast, lymphatic, gastric, prostate, and ovarian. It is believed that DHEA aids in slowing the growth of cancer. This hormone also blocks some of the enzymes that are responsible for cancer proliferation, which helps to prevent the activity of cancer and stops damage from occurring. Alzheimer's condition is extremely frightening, as it deals with the loss of memory and senility. It has been found that levels of DHEA in Alzheimer's patients are forty-eight percent lower than the normal, healthy level established by the control group. DHEA is responsible for protecting the brain cells from damage and deterioration. Also, it is useful with other degenerative conditions that deal with senility. In healthy individuals, DHEA can be found abundantly in brain tissue, which protects against aging and damage. DHEA is a precursor for cortisol and adrenaline, both of which are stress hormones. DHEA can become depleted when the body is under stress due to the effect on the adrenal glands. Because of this, chronic stress can lead to lower levels of DHEA, which can be detrimental to one's health. It has been found the prolonged stress can lead to cases of depression, with depression being helped by the addition of DHEA. Individuals with depression have found favorable results when using DHEA. It has been shown that DHEA therapy is free of side effects when taken in proper amounts. Some problems that occur when excess amounts of DHEA are supplemented include acne, rapid heartbeat, irritability, and headaches. The majority of people solve these problems by lowering the amount they are taking. For more information on the many beneficial effects provided by DHEA, please feel free to contact a representative from your local or internet health food store. Dhea is a hormone naturally found in the body now available over the counter at your local health food store. ~video~
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2130) Ginkgo Biloba
Date:
October 01, 2009 11:57 AM
In the past decade, ginkgo has received much attention. It has been revered throughout China and other areas of Asia for thousands of years. However, its popularity increased in Western countries. An increase in sales can be attributed to interest in the benefits of ginkgo on conditions that are associated with aging like Alzheimer’s, memory loss, dementia, and circulatory disorders. Often, gingko is used to increase the blood flow to the brain, which improves memory problems like Alzheimer’s, to prevent strokes, and to increase blood circulation through vasodialation. The improved circulation is also thought to improve ear conditions, help blood flow to the retina, aid in preventing muscular degeneration, reduce frequency of asthma attacks, and help transplant recipients avoid rejection. The ability of ginkgo to boost brain function has been studied extensively. Most importantly, ginkgo increases oxygen supply to brain cells, as the brain is the body’s most sensitive organ to oxygen deprivation. Additionally, ginkgo has been used to improve electrical transmission in nerves and supply more oxygen and nutrients to brain cells. The effect that ginkgo has on the brain and circulatory system disorders seems to be extremely promising for a variety of conditions. Ginkgo has also been found to be effective in treating migraine headaches. In one study that took place in 1975, ginkgo extract was given to individuals who were suffering from migraines. Results concluded that eighty percent of the patients showed improvement or were cured of the condition. Ginkgo extract has also helped dementia that results from poor blood flow to the brain. Senile dementia is often recognized by depression, unusual fatigue, and memory problems. Ginkgo has the ability to help improve circulation to the brain tissue, which in turn improves brain function. Blood platelet aggregation, or clotting, can cause serious problems in the body. Among these are strokes, heart attacks, and coronary thrombosis. It has been found that ginkgo can reduce the tendency for platelets to stick together and prevent them from forming clots in the arteries and veins. The brain and nervous system are extremely sensitive to free-radical damage because of the high percentage of unsaturated fatty acids. It has been found that ginkgo’s antioxidant activity is particularly powerful in these areas, along with the eye and retina. This is extremely helpful in conditions like retinopathy, cataracts and macular degeneration. The central nervous system possesses fat lipids in the cell membranes that are typically attracted by free radicals. Ginkgo can help protect these cell membranes and prevent condition which can occur in the brain and nervous system that are often associated with aging, like memory loss. The leaves of the ginkgo plant are used to provide adaptogen, alterative, antioxidant, antiseptic, and stimulant properties. Primarily, ginkgo is extremely helpful in treating ADHD, Alzheimer’s disease, lack of attention span, blood clots, cardiovascular disorders, poor circulation, dementia, dizziness, edema, impotence, inflammation, ischemia, memory loss, lack of mental clarity, multiple sclerosis, muscular degeneration, PMS, Raynaud’s disease, senility, stress, stroke, and tinnitus. Additionally, this herb is very helpful in dealing with allergies, angina, anxiety, arthritis, asthma, cancer, carpal tunnel syndrome, coughs, depression, lack of equilibrium, eye problems, hearing problems, hemorrhoids, lung disorders, migraines, mood swings, toxic shock syndrome, transplant rejection, varicose veins, vascular problems, and vertigo.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=2096) Detoxify With L-Citrulline
Date:
April 13, 2009 03:51 PM
L-citrulline is an alpha-amino acid, first isolated from the watermelon in 1930: hence the name, citrullis being Latin for that fruit, the skin of which is rich in the substance. It is used to enhance performance in sports, particularly through aiding recovery after exercise, and also helps the liver to detoxify the blood. It is not an essential amino acid in that it is produced by the body and need not be part of your diet. It is a precursor to arginine, which involves the sustained release of nitric oxide in the endothelium that promotes increased flow of blood and the blood vessels as described further below. One of the biochemical pathways for its biosynthesis involves the urea cycle, whereby the toxic ammonia is detoxified into an easily excreted form through its conversion to urea. The urea cycle consists of five reactions, and citrulline is formed in the second of these. In the first of these, ammonia reacts with bicarbonate to form carbamoyl phosphate, the phosphate coming from the two molecule of ATP used to energize the reaction. These are converted to adenosine diphosphate (ADP), and the carbamoyl phosphate then reacts with ornithine to form citrulline, which takes part in step three that eventually leads to the formation of urea. The second way in which L-citrulline can be biosynthesized is from the oxidation of arginine, a natural amino acid. Arginine is oxidized into N-hydroxyarginine, and then into L-citrulline with the release of nitric oxide. So that's how it is produced in the body, but how does it help sportsmen, and what part does it play in detoxification? Its effect on recovery after exercise is connected with blood flow. Energy is created in the mitochondria that are contained in every cell off the body. Among the raw materials needed for the production of energy are glucose and oxygen: glucose obtained from the carbohydrates in your diet, and oxygen transported by the hemoglobin or red blood cells. Both of these rely on blood flow: greater the volume of blood transported to the cells then the greater the ability of these cells to produce energy. During periods of exercise, a good supply of blood is required to provide the raw materials needed for the energy demand of the muscles involved in the exercise. Not only that however, but recovery after exercise involves the replacement of electrolytes, the glycogen used in extensive aerobic and anaerobic exercise and protein replacement, particularly where catabolism has occurred. In order to supply these raw materials at an adequate rate, it is necessary for the flow of blood to the appropriate muscles to be sufficient. A major restriction to increase blood flow is elasticity of the blood vessels and cells. Although a healthy heart is capable of providing the necessary quantities of blood, and hence of nutrients, any restriction to the flow could cause dangerously high blood pressure. Nitric oxide plays a signaling role in enlarging blood vessels to allow an increased blood flow when it is needed by the body. It can provide more blood to the stomach during digestion and to the muscles during exercise and recovery. During hard exercise, nitric oxide can act as a pump that provides blood during exercise and also during recovery. It can therefore provide more rapid gains in lean mass, increased endurance and faster muscle recovery. The way it does this is to send a signal to the smooth muscles to relax; smooth muscles such as those found in veins and arteries, so resulting in vasodilation therefore allowing increased blood flow. It is the endothelium, the inner lining of blood vessels, which uses the nitric oxide to provide the relaxation signal to the smooth muscles surrounding it. In fact, it is the effect of nitric oxide that enables those living at high altitudes to develop increased stamina and speed over those at lower altitudes, and find more world records seem to be broken during athletics meetings, such as Olympic Games, held at high altitudes. This is because the production of nitric acid is increased at higher altitudes with slightly lower oxygen levels. This is the same effect that is used by vasodilators such as amyl nitrite and Viagra that work by increasing nitric oxide levels in the smooth muscle wall of the blood vessels. It should not be surprising therefore, that L-citrulline should work in a similar way, since it is intimately involved in the production of nitric oxide. Although this is now generally understood, what part does supplemental citrulline play in the body if it is a non-essential amino acid? Supplemental L-citrulline is useful in supporting the detoxification of ammonia in the liver when supplies of ornithine carbamoyl transferase is naturally in short supply. This is the enzyme that catalyzes the reaction between ornithine and carbamoyl phosphate to form citrulline. Supplements can then help in the removal of ammonia from the blood, and also provide material for the continued production of nitric oxide support muscular activity and its recovery after exercise. Ammonia itself is a by-product of intensive exercise, and without the urea cycle the body would rapidly become polluted. It is a very toxic product, and causes the death of thousands of people each year. This is generally in people who suffer liver and kidney disease, and the ammonia can be broken down and excreted. Your brain cells are particularly sensitive to ammonia, and as levels increase the effect progressively ranges from drowsiness thru tremors to coma and eventual death. Any condition, therefore, that reduces the body's capability of metabolizing ammonia is potentially very serious, and any supplement that can help prevent this is valuable.
L-citrulline is believed to help in such situations, although any condition affecting the efficiency of the kidneys or liver and that can cause toxicity due to ammonia or any other toxic substance, should be referred to your physician. It is for its effect in increasing blood flow to provide sufficient raw material, for both the energy needed for high levels of exercise and for muscle recovery, that citrulline is predominantly used as a supplement.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1993) Alpha Lipoic Acid
Date:
December 11, 2008 11:19 AM
Alpha lipoic acid is the ideal antioxidant for five main reasons. It can scavenge free radicals of all kinds of both fat and water-based cell structures. It rapidly assimilates and absorbs into cells. Alpha lipoic acid boosts the action of other protective compounds. It chelates free meal ions and it also promotes normal cell replication. Alpha lipoic acid (ALA) is both fat and water soluble, which makes it a superior free-radical scavenger because it can protect lipid (fat) and aqueous (water) cell parts from free-radical damage. This ability allows ALA to offer excellent cellular protection because it can easily transport across cell membranes and give oxidant protection outside and inside cell structures. ALA has the ability to freely move throughout all cell parts, scavenging for free radicals in a way that is definitely more effective than other antioxidant compounds. Vitamin C, for example, is a good antioxidant but is strictly water soluble and only affects the interior of cells. On the other hand, vitamin E is only fat soluble, meaning that it affects only the lipid portion of cell structures or the membrane, which leaves other areas unprotected. Cellular glutathione, which is produced in the body and works to neutralize free radicals, is very difficult to artificially boost. Although oral glutathione supplements are available, they have to go through the GI route before they enter the blood stream, leaving little glutathione which actually survives this process. Because of this, cellular levels are not significantly increase by oral supplementation. ALA has been found to help regenerate glutathione by providing extra cellular protection. If the body becomes deficient in ALA, other antioxidant compounds may not work well. ALA plays an important role in boosting the activity of protective compounds such as vitamin E. ALA dramatically extends the life and effectiveness of other vital compounds. ALA has been used for decades to treat diabetic conditions and complications including diabetic neuropathy, with ALA actually having the ability to initiate a reverse in the condition in some cases. Additionally, ALA helps to boost glucose uptake and results in less insulin dependency in some cases. Among its other properties, ALA can protect brain tissue on a cellular level, as well as protect brain cells from certain hazardous chemicals. Research has shown that ALA may even play a role in the treatment of neurological disorders such as Huntington’s disease. As we are all aware, LDL cholesterol has a huge role in the development of cardiovascular disease. LDL cholesterol, which is particularly susceptible to free-radical damage, can be protected by ALA from free radical damage itself. Along with the above properties, ALA has been shown to help in strokes, cancer, cataracts, HIV, liver regeneration, and detoxification. ALA can be purchased in tablet and capsule form and works well when it is orally ingested so that it can be easily assimilated through the walls of the gastrointestinal tract. Taking between 40 to 50 mg of ALA is recommended for best results. The primary applications of alpha lipoic acid are aging, aids, alcoholism, atherosclerosis, bell’s palsy, cataracts, cancer, cirrhosis, diabetes, diabetic neuropathy, multiple sclerosis, liver disease, radiation sickness or exposure, Alzheimer’s disease, senile dementia, stroke, Huntington’s disease, Parkinson’s disease, and heavy-metal poisoning. Have you had your alpha lipoic acid today?
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1947) Horny Goat Weed
Date:
December 06, 2008 10:05 AM
Horny Goat weed, correctly named Epimedium, or Yin Yang Huo in Chinese, is one of over 60 herbaceous plants of the Berberdaceae family. It grows naturally in Southern China, and also in Korea, Southeast Asia and some parts of Europe. Other names given to include Fairy Wings and Bishop's Hat. Horny goat weed has been viewed as a natural alternative to Viagra, and many species of Epimedium are said to possess aphrodisiac properties, and is said to have got its name from a Chinese goat herder who notice that his goats became more 'frisky' with the lady goats after eating the plant. In fact studies have indicated to increase vitality, particularly the libido and male sexual vitality, although it also possesses some other health benefits in its effect on dementia and osteoporosis. The term 'horny' is used in the colloquial sense, and has nothing to do with the shape of the plant, the flowers of which are star-shaped. In fact the Chinese name for it means 'licentious goat weed', making the English translation quite clear. The main ingredient in horney goat weed is icariin, a flavonoid glycoside that acts as a PDE5 inhibitor. Others include the similarly named, but totally different chemical, icaritin, and also many other that will be discussed later. It is icariin on which we shall focus for the time being. Since this is central to its effect on erectile dysfunction, some time will be spent on explaining what PDE5 inhibitors do. cGMP (Cyclic guanosine monophosphate) is a chemical that relaxes smooth muscle tissue, including the vascular smooth muscles in blood vessels. This can lead to the dilation, or increase in size, of blood vessels and increased blood flow. The corpus cavernosum of the penis is a spongy area that runs the full length of the penis, and contains many blood vessels that can be dilated through the action of cGMP and allow the increased blood flow to create an erection. PDE5 (phosphodiesterase type 5) is an enzyme that can degrade cGMP and prevent the relaxation of these blood vessels, and so prevent them from dilating. A PDE5 inhibitor, such as icariin, prevents the PDE5 from degrading cGMP, and so allow a normal erection. Sidenafil, commonly known as Viagra, is a similar PDE5 inhibitor and works in the same way as icariin. Hence, the effect of Viagra is not to create an unnatural erection, but in fact to allow the cGMP to do its natural work by preventing the phosphodiesterase from stopping it doing so. This is just one of the effects of horny goat weed: it is a more natural PDE5 inhibitor than Viagra is. It is also more specific than Sidenfil, and does not interfere with any of the other phosphodiesterases that are essential for other purposes. However, its effects do not stop there, because icariin possesses other properties, and is also only one of the many components of epimedium that can increase vitality. Among these are a number of flavonoids in addition to icariin, sterols and the isoquinoline alkaloid magnaflorine, that possesses antioxidant properties and reduces LDL cholesterol. The exact mechanism by which horny goat weed works to increase sexual desire is unknown, but it is believed that it inhibits the enzyme acetylcholinetsrase (AChE). Cholinergic synapses are the spaces between brain cells that allow electrical impulses to be transmitted, and are an essential component of neuromuscular system response to stimulation. AChE can stop these from working properly, and prevent neurotransmitters from effectively allowing sexual arousal. Horny goat weed can inhibit the activity of this enzyme and allow the neurotransmitters such as serotonin, dopamine and norepinephrine to do their proper job in allowing sexual arousal to occur. This, again, is a natural and not a chemical solution. It has also been found to reduce cortisol levels that cause stress which also reduces sexual desire. The effect of Epimedium on smooth muscles can also aid those suffering from pulmonary hypertension, in which the small blood vessels in the lungs become too narrow to be effective in allowing the transfer between oxygen and carbon dioxide. PDE5 inhibitors can help these blood vessels to relax and so be more easily dilated in the same way as those in the corpus cavernosum. Once dilated, they are able to carry more blood to and from the lungs and allow the reoxygenation process to continue smoothly. Research has also discovered the possibility of horny goat weed possessing monoamine-oxidase inhibition properties. Monoamine oxidase enzymes can deaminate hormones such as dopamine, and can significantly reduce the production of testosterone. The inhibitor prevents this happening, and leads to elevated levels of dopamine, and also of serotonin and noradrenaline. Dopamine encourages the pituitary gland to release luteinizing hormone that in turn promotes the production of testosterone by the testes. Another property of horny goat weed is that it can protect against the toxin beta-Amyloid, a protein that damages DNA in the brain, causing the death of brain cells and the accumulation of dead cells in your brain. This in turn leads to dementia and potentially Alzheimer's disease. The use of Horny goat weed is being studied closely in relation to this property. The active ingredient here is icaritin (not to be confused with icariin) Epimedium also has implications in the treatment of the cartilage and bone damage that occurs with arthritis and osteoporosis. It is possible that this is connected with the antioxidant and anti-inflammatory properties of magnaflorine, and icariin has been found to have bone-healing properties. It is known that damaged cartilage treated with horney goat weed displayed signs of growth and regeneration when compared to a placebo. However, the most popular use of horny goat weed is in its effect on the libido and erectile dysfunction. The effect on the libido and sexual desire works equally well for men and women, and it is a preferred natural remedy to synthetic equivalents such as Viagra, Levitra and Cialis. The added benefits of the natural product render epimedium the preferred and safest solution for many people.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1945) Huperzine And Memory
Date:
December 04, 2008 01:20 PM
Chinese club moss goes by the name Huperzia serrata, and gives its name to the sesquiterpene alkaloid it contains: huperzine A. This alkaloid has been found to be a superstar in the arena of brain-saving treatments for conditions such as Alzheimer's and age-related senility. Studies in China have found up to 60% improvements in the cognitive functions of such patients, and its potential has been recorded in the Journal of the American Medical Association. This is no mere folk remedy, and is the subject of serious study. Known as Qian Ceng Ta, Chinese club moss has been a part of traditional Chinese medicine for centuries for the treatment of fever and inflammation, which is not surprising considering that most plants contain antioxidants and anti-inflammatories. However, what is unusual is the fact that it has also been found effective in treating some forms of dementia and depression, and also helps to reduce the incidence of panic attacks in those susceptible to them. Not only that, but the plant has been found to possess diuretic properties, and a reduction in the swelling associated with water retention could also help to reduce the pain and other effects of swelling and inflammation. However, for now it is its effect on the brain that we are concerned, and research has indicated the likely mechanism by which huperzine A works. Huperzine is an enzyme inhibitor - specifically inhibiting the enzyme acetylcholinesterase that breaks down acetylcholine, a neurotransmitter involved in the processes of memory, learning and mood. Outside the brain, it is involved in the movement of skeletal muscle tissue as well as in the regulation of cardiac and other smooth muscles such as those of the blood vessels. When acetylcholinesterase (AChE) attacks acetylcholine (ACh), the latter attaches to a chemical site on the enzyme where it is then destroyed. It is a deliberate function of the body, designed to terminate a synaptic transmission. The purpose of a neurotransmitter is to allow the transmission of an electrical impulse form one nerve cell to another over a gap between them known as a synapse. Once the transmission has been completed, the enzyme can destroy the neurotransmitter, and then another takes its place. In fact one molecule of AChE can destroy around 5,000 molecules of ACh. However, with age and for other reasons, these neurotransmitters can become depleted so that it becomes increasingly more difficult for brain cells to communicate with each other, and their destruction becomes undesirable. There are drugs available to help prevent this happening (e.g. donepezil, galantamine and tacrine), and so help to improve the memory and mental function of people as they grow older or contract conditions such as Alzheimer's disease. Huperzine A has been found to take up the site in the acetylcholinesterase molecule that would normally have been used by the acetylcholine, and so save it from destruction. The more Huperzine A molecules present, the more acetylcholine available to pass messages between brain cells, and the stronger the cognitive function of the subject or patient. The pharmaceutical drugs mentioned in the previous paragraph work in exactly the same way. This is a very specific reaction, one molecule adopting exactly the same space as the other, and has been proved scientifically by comparing the physical shapes of the two molecules. It's just like a jigsaw puzzle, where only one piece can fit into each position. Except here there are two: Huperzine A and acetylcholine both fit into the exact same place in the chemical structure of the acetylcholinesterase molecule. The biochemistry of the reactions involved is very complex, and shall not be discussed here, but the upshot is that Huperzine A can do exactly the same job as modern drugs to avoid this hydroxylation of the ACh needed for the proper functioning of your brain. In fact, clinical trials have indicated Huperzine A not only to be comparable in effect to the drugs current used, but also likely safer with respect to the possible side effects. This has still to be confirmed, but the National Institute on Aging is currently carrying out a trial to evaluate this claim in tandem with its effect on Alzheimer's disease. It has also been examined at Harvard University for its effect on epilepsy on patients with whom alternative pharmaceutical treatments have been unsuccessful. Another suggested benefit of Huperzine A is that it is an NMDA (N-methyl D-aspartate) receptor antagonist that provides protection against damage to the brain by an excess of glutamates, and that it can also help to protect nerve cells from damage. Since NDMA is responsible for the transmission of some types of pain, the antagonist can also act as an analgesic. There are other benefits that Chinese club moss can provide, and myasthenia gravis is one of them. Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells. This is achieved through the autoimmune system malfunctioning and creating antibodies against the receptors, and the end result is paralysis and respiratory failure. Huperzine A reduces the AChE available and so might possibly enable the acetylcholine to work more effectively and delay or even stop the deterioration of muscle function. When people hear of muscle paralysis they frequently forget that breathing requires muscle function, as indeed does your heartbeat. This is currently surmise, and studies are being carried out to determine whether or not this usage of Huperzine A is viable. Another promising application of Chinese club moss extract is in preventing organophosphate poisoning. These pesticides permanently suppress acetylcholine. This results in seizures due to a lack of interruption of the signals from nerves to muscles. The seizures can result in rapid death from uncontrollable seizures, or from permanent contraction of the diaphragm muscle that allows breathing. Although no human studies have yet been carried out, animals given Huperzine A prior to organophosphate exposure have survived without seizures. There are no doubts that Chinese club moss and the Huperzine A extracted from it are effective in preventing the suppression of acetylcholine, and in permitting the proper activity of this important neurotransmitter. It is finding an increasing number of potential uses beneficial to the human body, not the least of which would be a partial remedy for some of the effects of dementia and Alzheimer's disease.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1944) DHA for Attention and Focus
Date:
September 29, 2008 05:33 PM
Attention deficit/hyperactivity disorder emerged in scientific research at the turn of the 20th century when Dr. George Still was introduced to a disobedient, troubled, nine year-old boy. Today, research still just touches the edge of this serious disorder, but our understanding has steadily grown throughout the 20th century. Dr. Still believed that ADHD is not just the result of bad parenting, but also of some sort of condition in the brain. The symptoms that comprised ADHD were considered minimal brain dysfunction or minimal brain damage in the 1940s or 1950s, while others called it hyperactivity. By 1987, scientists were referring to the condition as ADHD. Today, no one has yet to pinpoint the exact cause of ADHD, but there has been some interesting research that has lead to the discovery of many different facts. Identical twins are much more likely than fraternal twins to both suffer from ADHD, as identical twins share genetic material, causing researchers to believe that ADHD may have a genetic component. A study of adults with ADHD showed that ADHD brain cells were less active by eight percent and used glucose less effectively in the areas of the brain that involved attention control. About seventy percent of ADHD children continue having ADHD when they become adults. Additionally, a study found that fifty-seven boys with ADHD suffered from a slight structural abnormality in the brain, with the prefrontal cortex, caudate, nucleus, and globus pallidus being slightly smaller on the right side than in fifty-five boys who didn’t suffer from this disease. All of these areas are parts of the brain that are believed to inhibit our actions. The American Psychiatric Association says that children can have ADHD if they have six or more of the following symptoms of hyperactivity, impulsivity, or inattention for six months or longer. Other possible symptoms include: frequently not paying close attention to details; frequently having trouble staying focused on tasks; frequently not following through on instructions; frequently having difficulty organizing duties and activities; frequently failing to listen when directly spoken to; frequently avoiding or hesitating to be involved in tasks requiring continued mental effort; frequently losing objects needed for duties or activities; frequently distracted by external stimuli; and frequently forgetting daily activities. Other symptoms of hyperactivity and impulsivity would include: frequently fidgets with hands or feet; frequently squirming while sitting down; frequently leaves seat in places where remaining seated is the accepted norm; frequently running around or climbing in places that are inappropriate; frequently having difficult playing quietly; frequently appearing on the go; frequently speaking excessively; frequently blurting out answers before questions are completed; frequently having trouble waiting his turn; and frequently interrupting conversations or games with others.
The most commonly prescribed treatment for ADHD is medication, often being Ritalin, which is a stimulant that helps to enhance the effect of the brain chemicals that help nerve and brain cells to receive messages from each other. Ritalin can help ease the suffering of a child with ADHD, making them more attentive and less aggressive. However, there are many drawbacks to the use of Ritalin, which include it being a form of amphetamine, becoming a popular drug to abuse, having many significant side affects, and being psychologically addictive. Natural alternatives are available such as Dha or essential fatty acids which are suppose to promote proper brain function.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1904) Ginkgo Biloba Extract
Date:
September 19, 2008 09:25 AM
Ginkgo biloba, also known as the maidenhair tree, grows naturally in two small areas of Eastern China. It is believed that even these sources are artificial, and planted and maintained by monks over many centuries, and that there are no true natural sources of the tree left. Other than these, all living ginkgo trees are now artificially farmed. The ginkgo seeds contain nuts that are a traditional food in China, served at Chinese New Year, and on other special occasions such as weddings, and is also used in traditional Chinese medicine. The seeds have been used in the treatment of coughs and asthma, and during the late 1970s and 80s, the uses of ginkgo biloba in medicine was extensively investigated with a view to determine the range of conditions that the tree could be used to treat. Given that many ancient Chinese remedies have found to be effective, and with a relevant scientific basis, this was a logical step. It has been established that ginkgo biloba could have three possible effects on the body. These are:
* Improvement in circulation including that in the small capillaries. The last of these has been responsible for many cardiovascular conditions, and disorders of the kidneys, lungs and central nervous system, and is due to the effect of the platelet-activating factor (PAF) that ginkgo appears to inhibit. Before delving deeper into the possible beneficial effects of Ginkgo, let us first examine the active ingredients believed to be involved in the perceived beneficial effects. Ginkgo leaf extract contains terpenoids (bilobalides and ginkgolides) and flavonoid glycosides. Flavones can reduce the fragility of capillaries, and protect the body from blood loss through damaged capillaries, particularly in the brain. The Ginkgolides, particularly ginkgolide B, inhibit the platelet-activating factor and so increase the fluidity of the blood that improves circulation, again particularly in the micro-capillaries of the brain. This is also why it is believed to reduce the incidence of cerebral thrombosis and resultant strokes. The antioxidant effect of ginkgo biloba extract (GBE) has been widely studied, and by scavenging free radicals the extract can help to prevent cell membrane damage, and so prevent cells from being destroyed. It has been established that pretreatment of cells with GBE can prevent such damage in rats. The anti-inflammatory properties of ginkgo biloba, as seen in some asthma patients for example, is thought to be due to the inhibition of the platelet-activating factor (PAF) by ginkgolide B, PAF playing a significant part in the inflammatory response to allergens, and PAF is now believed to be responsible for conditions such as asthma, renal diseases, central nervous system disorders and ischemia, a restriction in the blood supply, particularly to the brain. It follows, therefore, that the effect of GBE on these conditions is likely to be due to PAF inhibition, and a reduction in the inflammatory response to a number of conditions. What evidence is there for this? In fact, results of the trials carried out have been inconclusive one way or the other. Hence, a trial published by the Journal of the American Medical Association reported no effects after a 6 week trial of Ginkgo on Alzheimer’s and memory disorders. However, other trials have indicated positive effects after 6 weeks, and it could be that the GBE has to be taken for more than 6 weeks for any effects to be noticed. It is certainly believed to be a longer term treatment rather than have instant results, although some tests have shown improvement in concentration for up to 2.5 hours after treatment. The bulk of the evidence is favorable on the effect of GBE on memory disorders. Test on rats, in which the blood flow to the brain was mechanically blocked by carotid compression, indicated that ginkgo biloba promoted an increase in the glucose and ATP levels in the brain neurons. Other trials have indicated that neurological damage in mice subjected to neurotoxins was reduced by the administration of GBE, and while not conclusive with respect to humans, the effect of GBE on the brain appears to be more than just opinion. To sum up, ginkgo biloba is believed to be effective in treating the following disorders by virtue of its effect in improving the fluidity of the blood, protecting fragile capillaries from damage, exerting an antioxidant effect on free radices, and so prevent damage to cell membranes, and its inhibiting effect on platelet-activating factor: Circulation Problems Circulation problems in the arteries can lead to blood clots that in turn cause strokes and cardiac problems. By preventing blood clots through the inhibition of PAF, ginkgolide B can help to maintain a healthy circulation system that also help to maintain circulation in the very small capillaries that feed the brain. Atherosclerosis This is caused by hardening and blockage of the arteries, and one of the effects of ginkgo biloba is to soften the arteries, help to unblock them and to prevent plaque formation by its antioxidant effect on the free radicals that cause the plaque by oxidation of LDL lipids. This is particularly true of the cerebral arteries. Memory Impairment The increased blood flow to the brain that GBE promotes can help to improve memory, although test are indicating that treatment has to continue for 6 weeks or more for it to be effective. Reduced blood flow to the brain is a common cause of memory impairment. Alzheimer’s disease Ginkgo biloba has been used in the treatment of the symptoms of this condition, although it cannot be cured. It is thought that the improved circulation in the brain makes best use of the unaffected brain cells, improving memory and cognitive thought. Reynard’s Disease This is a condition where the extremities fail to warm up after being exposed to cold, and is caused by poor circulation in the small capillaries in which the blood pressure is very low. They symptoms are numbness and pins and needles, and GBE helps to overcome this condition due to improvement in the circulation and protection of the capillaries by rendering them less fragile. Vertigo GBE can help to reduce the symptoms of vertigo such as nausea and dizziness. This is believed, once again, to be due to an improvement in blood circulation.
There are few doubts that ginkgo biloba extract improves the circulation, particularly in the micro-capillaries in the brain and extremities of the body, and also possesses antioxidant properties, both of which help to maintain and improve the memory, and that combined with its effect on the platelet-activating factor, most of the properties of GBE is due to its capacity to maintain and improve circulation, particularly through those blood vessels closest to the blood-brain barrier.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1894) GABA
Date:
August 26, 2008 04:58 PM
GABA is gama amino butyric acid, and is an inhibitory neurotransmitter that is essential for the proper function of your brain and the central nervous system, and has the effect of reducing excessive brain activity and promoting a state of calm. For many people, the rush of daily life, with its problems, worries and external stimuli, can over-stimulate the brain to the extent that it can all seem too much for them. They feel anxious and overwhelmed, and wish that they could just go into a quiet corner to get away from it all. Most people have felt like that at some time, but the demands of life do not allow them that luxury. They just have to bear it and get on with life. That is where GABA can come in. It can be used to bring your nervous system back to base, and make you feel more relaxed, calmer and more able to meet these challenges that life often throws at you. When you feel that you just can’t relax or concentrate on what you are doing, GABA can help you. If you look around you and everybody else seems OK, without apparently feeling the stress and irritability that you feel, and then perhaps your problem is due to a GABA deficiency. GABA is the principal inhibitory neurotransmitter in your brain, and a deficiency would certainly give you the symptoms that you are feeling. Let me explain why. As your brain becomes excited, it can run out of control and needs some form of modification or inhibition to keep it acting as normal. Without this you would become increasingly more restless and irritable, and ultimately have seizures. GABA is not only the main inhibitor in your brain, but also helps in the production of endorphins that provide you with a sense of well being. That sense of calm you feel when endorphins are produced, for example during exercise or sexual intercourse, is commonly referred to as the ‘endorphin effect’. GABA is at its highest concentration in specific areas of the brain, including the hypothalamus, the hippocampus and the central brain area, and is present in up to 40% of all synapses, the small gaps between neurons across which brain cells can communicate with each other. It is produced during the Krebs or Citric Acid Cycle that is responsible for cell respiration or the production of energy from carbohydrates. It is synthesized from alpha-keto glutarate, which is produced just before the Succinyl Co-A stage of the Krebs Cycle in the brain. Vitamin B6 in involved in its metabolism, and a Vitamin B6 deficiency can lead to a deficiency in GABA that might result in seizures. Basically GABA works by inhibiting the firing of neurons in your brain, and thus reducing general brain activity. The GABA receptor allows more chloride ion to enter the brain cell, thus helping to maintain the electrical charge within the cells. Bezodiazepines (e.g. diazepam) work by increasing the effectiveness of GABA in opening the chloride ion cells to allow more chloride ion to enter the neurons, and caffeine does the opposite, and inhibits this property of GABA. Thus diazepam works as a minor tranquilizer and caffeine as a stimulant. Alcohol has a similar effect to the benzodiazepines, increasing the release of chloride into the neurons, and is the major way in which alcohol affects the brain. In fact, tolerance to drugs and withdrawal symptoms can be explained by the receptors adapting to the drug. They may increase in number, which means that more of the drug is needed to work on them, and they can become hypoactive in the event of the drug being withdrawn, that enhances the symptoms that the drug was intended to treat. So basically, that is the way that GABA works. In simple terms it increases the flow of chloride electrolyte to the brain, and in so doing affects our mood. This effect is enhanced by prescription drugs such as Valium and Ativan, which are used by those that suffer the effects of a GABA deficiency. However, these drugs have side effects, not the least of which is dependency due to the GABA receptors becoming modified to suit the drug. There is a more natural way to overcome many stress problems and symptoms of mood swings. Knowing what causes these symptoms, it makes sense to eat foods that stimulate the creation of neurotransmitters to replace those that are deficient. Since GABA is produced in the Krebs Cycle and complex carbohydrates produce glutamine that is an important part of that Cycle, and is also the precursor to GABA, then the consumption of such foods should in theory produce more GABA. In this case the theory works, and you should eat foods rich in complex carbohydrates such as whole grains, brown rice and oats as part of your diet. Other foods that are high in glutamine or its precursors, glutamic acid and glutamate, include citrus fruits, beef liver, broccoli, halibut and lentils. A useful supplement to take is L-theanine, an amino acid found in green tea, and available in supplement form. L-theanine can calm your nerves while maintaining clarity of thought. In other words it calms you down, but doesn’t make you drowsy and allows you to enjoy your day with anxiety. Your doctor can determine whether or not you have a neurotransmitter deficiency through a simple urine test, and might also test your saliva for hormone content. A GABA supplement might be indicated, and if so it other beneficial effects on your body other than its effect on your brain cells. It improves your sleep cycles and promotes vivid dreaming, and can also have a positive effect on your blood pressure. It is also an effective pain killer, and can provide relief from such conditions as back pain and arthritis. Its stimulating effect on the anterior pituitary gland to secrete Human Growth Hormone might also be regarded as a benefit by many. Increasing the level of HGH in your blood can lead to fat loss and improved anabolic activity (increase in muscle tissue). This can be of benefit to older people whose level of HGH secretion has dropped off, and who find it more difficult to lose fat. GABA is a substance that has many known benefits and no known side effects other than a slight tingling and increase in heart rate when the supplement is first used. It has a definite benefit for people to whom the world seems too hectic and overwhelming.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1875) DHEA
Date:
August 15, 2008 11:53 AM
In the recent past, DHEA has shown scientists its amazing abilities within the human body. Clinical tests have created a huge amount of interest for both scientists and consumers, with estimates of about 500 in-depth clinical studies on DHEA taking place. These tests, which have been conducted at some of the most prestigious medical research centers and universities in the country, have proven DHEA to be one of the most important anti-aging and anti-disease substances of the 21st century. DHEA is a crucial and important hormone that is produced in the adrenal glands. It is often called the mother hormone, as it forms the base for the biochemical actions of hormones like testosterone, estrogen, progesterone, and corticosterone. These hormones control important body functions that determine metabolism, energy output, endocrine mechanisms, and reproductive capabilities. DHEA directs the entire endocrine systems through activating and inhibiting enzymes. In its many clinical studies, DHEA has shown an unusually wide variety of physiological benefits. Although it has been known for many years that DHEA is made by the adrenal glands, the function of DHEA in the body has only been recently studied. DHEA is produced by the adrenal glands, but it can also be found in non-patented prescription drugs and other over-the-counter forms. A lot of these supplements contain a synthetic DHEA-S. A lot of people consider Dioscorea extract, which can be found in Mexican Wild Yam, to have a natural source of DHEA. There are a lot of naturally occurring compounds that can mimic the actions of DHEA and, at the time, do not require a prescription. Wild Yam and Mexican Yam can give a botanical precursor of DHEA, which is considered a substantial source by a lot of health advocates. A great number of studies on DHEA that is derived from Mexican Yam have been conducted, with results concluding that DHEA derived from Mexican Yam and Dioscorea extract is a great idea. However, some controversy surrounds the value of Wild Yam as a valuable source of DHEA. DHEA is used in the body to make other hormone, as it is the most dominant of all the hormones present in the body. It contributes to the proper growth of brain cells, inhibits the conversion of carbohydrates to fats, decreases the formation of blood clots, regulates hormones, decreases the stickiness of platelets that can clump to cause heart attacks and strokes, increase estrogen in women and testosterone in men, lowers LDL cholesterol, enhances overall immunity, and decreases symptoms of an enlarged prostate. DHEA helps to reduce menopausal symptoms, promotes thermo genesis, helps to increase muscle mass, stabilizes blood sugar, inhibits appetite and discourages eating, boosts endurance, inhibits diseases associated with aging, helps to restore collagen and skin integrity, fights fatigue and depression, helps to inhibit certain tumors, improves calcium absorption to discourage osteoporosis, acts as an anti-inflammatory, and helps to lower blood pressure. DHEA levels dramatically vary in each individual and can drop as a result of stress or other conditions such as blood sugar, fever, hypertension, nicotine ingestion, alcohol consumption, drinking coffee, and the presence of various diseases. Taking birth control pills and other synthetic hormones can also deplete levels of DHEA. When any of these occur, supplementation is needed. Therapeutic doses range from 5 to 25 milligrams per day which can be found here at VitaNet, LLC.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1867) Depression and Vitamins
Date:
April 17, 2008 11:20 AM
Most men dealing with depression have stories that are very similar, waking with a heavy head even in the happiest of times. A bad day is described as one in which you can’t get out of bed and it feels as if there is a dark cloud hanging over your head. Today, as the NFL season moves towards playoffs, many athletes are living with depression related to multiple concussions. A study of over 2,500 retired NFL players concluded that three concussions triple the chance of experiencing depression. This is extremely important in a sport in which brain trauma is so often and easily dismissed. Just like helmets cover the faces of men playing a violent game, the angry aggression that is so commonly associated with normal guy behavior may actually be a mask for depression and physical injury is not needed to suffer its effects. It has actually been discovered that depression is more common in men than anyone ever knew, as male depression has often been under-diagnosed because the standard diagnostic manual portrays the depression symptoms more commonly associated with women. About six million men will be diagnosed with depression in 2008, not counting the one million more that will go undiagnosed. The sad weepiness that is commonly associated with depression is much more commonly found in women, while a man is more likely to be short-tempered, fatigued, and uninterested in sex, work, or hobbies. However, it is work that provides depressed men a distraction to their painful inner feelings. Men are more likely to try downing their pain in alcohol or drugs instead of getting treatment. Untreated depression explains why the male suicide rate is more than four times the rate of female suicide. Although there are hormonal differences in depression of the different genders, the common factor is stress. Although some men are open to being told they are depressed, most only act out with more anger. An effective, but not exactly subtle approach to telling a man he may have depression is leaving and article or book around the house for him to pick up. Severe depression requires immediate attention by a trained practitioner, along with various medical interventions. Once the worst is over, it is important to try to maintain a depression-free lifestyle. This can be done by reduction stress and finding social support as well as dietary changes. This is a difficult step for men who are used to conversations which revolve around scores and transactions, but good places to start are men’s groups at houses of worship (church) or those groups such as AA if substance abuse is part of the problem. By fortifying the brain with depression-fighting nutrients, including a B vitamin complex, one can maintain and promote normal mental functioning. Many depressed people are extremely deficient in folic acid as well as dietary essential fatty acids. Omega-3 fatty acids are needed to build healthy brain cells, along with phosphatidyl serine. Other herbs, including eleuthero, rhodiola, and ginseng, can help the body to adapt to stress, while St. John’s wort and SAMe work as natural antidepressants.
The most severe mistake that can be made is to play down depression, which applies to raging men just as much as it does to weeping women. Both genders need to seek help if feeling this way. If you feel you are experiencing depression, seek professional help as well as look into dietary changes, exercise, and the support of family can be a good start to a healthier outlook on life.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1759) Blue Green Algae a Super Food that is Foods Packed With Nutrients. Vegetarian Friendly
Date:
April 11, 2008 11:24 AM
In the USA it is harvested in Oregon, in the upper regions of the Upper Klamath Lake, although it is also available in many other parts of the world. Blue green algae are about the best source of vegetable protein and amino acids available to the human diet, although are now generally used as a supplement rather than as a primary food source. However, in spite of its name, it is not an alga at all: it is a bacterium: Aphanizomenon flos-aquae (AFA), known as cyanobacteria, after the Greek for blue. Nevertheless, bacteria or not, blue green algae offer exceptional nutritional benefits and also health benefits to people suffering from certain conditions. Here are the best of its benefits: 1. It is natural and therefore easily assimilated and digested. You get a very high useful yield from its nutrient content, unlike other foods where a large proportion can be passed through the gut unchanged. In fact a large proportion of the food you eat passes through your body unchanged, although that is mainly due to a lack of chewing! 2. It is very high in protein, and helps to maintain healthy hair, nails and skin. If you are on a vegetation diet this is an ideal source of non-animal protein (unless you class bacteria as animals!). If you want numbers, at least 60% of the solid content of this material is vegetable protein human-ready for use. 3. It is packed full of enzymes that aid digestion, and so ensures that not only is it itself fully digested, but also that you get the most nutritional benefit from any other foods you eat. A lack of enzymes is very common in the western diet, especially the North American diet, and if you take a regular supply of blue green algae, then you need not also take enzyme capsules. 4. It possesses cleansing and detoxifying properties, and so helps to reduce the incidence of headaches and allow you better and more restful sleep. Toxins can act on your body to cause pain, and is associated with the free radicals discussed below. 5. It is very high in antioxidants that destroy the free radicals in your blood and tissues. Free radicals destroy body cells and can seriously damage your health. Among the health benefits that blue green algae provide due to its antioxidant properties are: a) It supports the immune system and helps to prevent inflammation in your joints. It also enables you to fight off bacterial and viral infections quicker. b) It maintains the integrity of your body and skin cells, and reduces cell damage by free radicals. This has an anti-aging effect and preserves the youthful appearance of your skin, resisting wrinkling and maintaining its firmness. c) Blue green algae help to prevent the free radical oxidation of the LDL lipids that transport cholesterol that cause the atherosclerosis that can lead to heart attacks and strokes. 6. It provides you with energy through its effect on your body’s metabolic conversion of blood glucose to energy within the mitochondria. This is partially due to its antioxidant effect and partially to the nutritional content of the bacteria. The bacteria are also a rich source of glycogen that is your body’s store of emergency energy. Your liver can use the bacteria to biosynthesize its own store of glycogen that your body can use if called upon for a sudden burst of energy. 7. The amino acids it contains are of low molecular size, and can cross the blood-brain barrier. It provides nutrition to the brain, and its high chlorophyll content helps to purify the blood. Its high content of trace minerals and naturally chelated minerals renders them extremely bioavailable, and able to provide a high degree of nutrition to the brain and other organs of the body. Blue green algae contain rhamnose that helps nutrients to cross from the blood to the brain, and then to the brain cells that need it. 8. Blue green algae have been shown to help memory and mood. This is likely due at least in part to its fatty acid content, and its effect on serotonin levels. These eight benefits are more than any other individual food source can provide, and in themselves justify the claim that blue green algae is the best individual food source there is. However, when we have a look at the active ingredients, and nutritional content of the bacteria, then it seems even more impressive. There is more to blue green algae than just a few vitamins and minerals. You can get these in any multivitamin supplement: this stuff is completely natural and all of its ingredients are completely compatible with the human digestive system. Many of the synthetic vitamins you find in boxes and tubs are only partially absorbed due to the form they are in. Either that or they need the presence of other substances before they can be assimilated. An example is calcium, which is next to useless without magnesium and vitamin C also being present to allow it to be incorporated in the structure of the bones and teeth. With blue green algae, every combination of substances that nature needs for them to work properly is there. Everything gets used and everything has a role to play. The amino acids and proteins have already been mentioned, and these unusual bacteria contain all of the trace minerals that are necessary for the amino acids and proteins to be properly used. It also contains a large quantity of beta-carotene (a natural Vitamin A precursor and strong anti-oxidant), and is also rich in Vitamin B-12 that most vegetarians are deficient in. It is therefore the perfect food for vegetarians and vegans. If you understand the health benefits of omega 3 and omega 6 fatty acids, which blue green algae are also rich in, then you will understand how a foodstuff containing these fatty acids and all of the other nutritional substances listed above could be regarded as a ‘Superfood’. Blue green algae is probably the richest food available commercially to humans, but before you use it you should ensure that the content of blue algae in the supplement you purchase is clear and that you are purchasing a standardized amount in what you are purchasing.
Otherwise, it is difficult to see how anybody could go wrong with blue green algae, since it is indisputably an excellent source of protein, amino acids, vitamins and much, much more.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1752) Leci-PS - Boost Brain Power
Date:
April 10, 2008 06:03 PM
Phosphatidyl serine (PS) is an important phospholipid that is present in every biological human membrane, and therefore vital in the support of all the body’s major systems. While it plays an important role throughout the body, it is of considerable importance to the human brain. PS is actively involved in billions of neurotransmissions taking place every second within the body. its unique size and structure allows it to cross the blood-brain barrier to transfer supporting nutrients and remove waste. The brain, like every other organ, needs nutrients to function properly. PS makes it possible for these nutrients to reach their destination, by improving the quality of transmission, clearing the paths upon which they travel, and protecting brain cells from free radical corruption. Unfortunately, as the body ages, its natural production of PS steadily declines. Phosphatidyl serine’s cognitive health benefits have also been recognized by the FDA, as evidenced by a qualified health claim stating that, “consumption of phosphatidyl serine may reduce the risk of dementia in the elderly. Very limited and preliminary scientific research suggests that phosphatidyl serine may reduce the risk of dementia in the elderly.”* Considering the vast importance of this important biological multi-tasking phospholipid, NOW is devout in using only the finest phosphatidyl serine raw materials when formulating their products. Leci-PS®, a product of Cargill Incorporated, has established itself as the absolute highest grade available. Leci-PS® contains 90% phosphatidyl serine thus offering the highest concentration PS available anywhere within the natural product industry. It has been named GRAS (Generally recognized as safe) by the US Food And Drug Administration, and is manufactured in Cargill’s state-of-the-art GMP-Certified facility.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1751) Alpha Lipoic Acid is a Powerful Antioxidant
Date:
February 15, 2008 02:55 PM
The discovery of alpha lipoic acid at the University Of Texas Chemistry Department in 1951 was not heralded with trumpets of joy at the revelation of such a powerful antioxidant, but was instead largely ignored. This is largely due to the biochemistry involved not being fully understood at that time, but by the 1980s it was a commonly used supplement, recommended for several medical conditions. Chemically, the substance is a 5-membered cyclic disulphide with a carboxylic acid grouping. Biochemically, it’s extremely powerful antioxidant properties are largely due to the fact that it one of those rare active molecules that are soluble in both water and fats, and in fact is the only such antioxidant currently know. One of the properties that this ability enables it to possess is to cross the blood-brain barrier, and apply antioxidant propertied to the brain. Antioxidants are essential to human life in that they destroy free radicals. These are compounds with free unpaired electrons that destroy human body cells in their hunt for electrons to pair with. Electrons come in pairs in organic animal tissue, just as they do in organic compounds. However, under certain circumstances this pairing can become destroyed, leaving a molecule with one of its electrons without a partner. The factors that lead to this situation are many and varied, and our own biochemistry can produce free radicals during the normal chemical processes of life. However, pollution can also lead to the oxidation processes that create free radicals, common such pollutants being cigarette smoke, vehicle exhaust fumes, pesticides and the like. Excessive exposure to the UV content of sunlight can also create free radicals as can eating barbecued and smoked foods, and exposure to carbon monoxide and peroxides. Even the biochemical conversion of glucose to energy in our bodies creates free radicals. These free radicals can destroy body cells, including DNA, and can create conditions such as premature aging due to destruction of skin cells, destruction of brain cells, strokes, cancers, diabetes, atherosclerosis due to oxidation of LDL cholesterol that deposits in the main arteries of the body, stiffening of the joints and many other undesirable conditions. Free radicals are destroyed rapidly by antioxidants: the reaction is very rapid and most are destroyed immediately they are formed before they can do harm. Fortunately, if your diet is well maintained, the body possesses many antioxidants such as vitamins A, C and E, and other substances such as Coenzyme Q10, flavanoids, xanthenes, polyphenols and carotenoids. Many of these are found in highly colored foods, and if your food is brightly colored, it should contain a good supply of antioxidants. However, the problem with all of these is that they are either fat and oil soluble or water soluble, which means that they can either be freely carried round the body by the blood or have to be emulsified by the bile and transported via the lymphatic system that places restrictions on their effectiveness in certain organs of the body. The fact that alpha lipoic acid is soluble in both water and fats enables it to be carried to all parts of the body and to every organ, and can cross water/fat barriers that other antioxidants cannot do. It can therefore be carried via the blood to the brain and carry out an essential antioxidant function within our brains. It took a long time for this property of ALA to be recognized and its consequent health benefits understood. It is, in fact, the ideal antioxidant. The substance provides many known benefits to the body due to its antioxidant properties and also helps the body to generate the maximum possible amount of energy from the blood glucose and thus improve the energy balance of your body. However, it is with its antioxidant properties that we are most concerned here. One of the benefits of these properties is its effect in holding back the visible effects of aging on your body. Because it is both water and fat soluble, alpha lipoic acid can help destroy free radicals in every part of your skin; the areas served by the blood and the fatty and oily secretions are protected simultaneously by the same strong antioxidant. The end result is a reduction in the destruction of the cells through the dermis and epidermis and a reduction in the degree of wrinkling with age. Its antioxidant effect in the brain renders ALA in great demand for reducing cognitive impairment with age. In fact studies have indicated that alpha lipoic acid can improve memory and brain function in the aging and the elderly. This effect appears to be increased by the synergistic combination of alpha lipoic acid and acetyl-L-carnitine that work together to prevent cognitive decline in the brain through the effect of free radicals. There is evidence that during a stroke, ALA works synergistically with vitamin E to reduce the effect of free radical damage on the vulnerable brain cells, and so reduce the longer term effects of the stroke. Together with ALC, it also reduces oxidative stress on the mitochondria of cells and in so doing helps once again to reduce the effects of aging, and maintain the body’s capacity to generate energy from blood glucose. Cardiovascular disease is the main killer of the western world, largely due to our diets, and this is especially true of the USA. Although Americans appear unable to change their unhealthy diet, alpha lipoic acid and acetyl-L-carnitine can be used to offset much of the damage done. ALA reduces the development of atherosclerosis through its antioxidant properties and the reduction of the adhesion of monocytes to the artery walls. LDL trapped in the wall of the artery can be oxidized and enable monocytes to also enter under the surface of the arterial wall, where it changes into macrophages and ingests the oxidised LDL, causing the plaque that forms atherosclerosis. As the plaque thickens, the artery becomes increasingly restricted until the blood flow is significantly reduced or even stopped, causing cardiac failure or a stroke. Alpha lipoic acid can prevent this free radical oxidation from occurring by destroying them before they act on the low density lipoprotein (LDL). Acetyl-L-carnitine works with the ALA to achieve this, as does another substance known as carnosine. Between them, these three musketeers work to keep your arteries clear and your brain functioning as it should, though it is the ALA that is most powerful due to its oil and water solubility properties. Although alpha lipoic acid is available as a supplement, either alone or in combination with acetyl-l-carnitine, it is also available from natural food sources. It is particularly rich in offal such as heart and kidney, and also in broccoli, spinach and brewer’s yeast. It is also available in beef, and it is here that burgers can perhaps repay some of the damage that it causes. However, it is not a recommended source since burgers still cause more damage to your health than any of their constituent nutrients can allay. Like any other supplement, you should seek medical advice before taking any substance if you have a health condition. Nevertheless, the benefits of alpha lipoic acid are such that it is difficult to see it doing anything but good. However, please consult your physician if are taking other drugs.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1718) Acai: The Super Antioxidant From Brazil
Date:
February 03, 2008 02:07 PM
Acai is an Amazonian palm tree, and possesses small purple fruits that the Amazonian natives of Brazil have used since time immemorial as food and as a remedy for certain health conditions that are now known to be associated with the activity on free radicals on body cells. The active constituents of acai are powerful polyphenols and anthocyanin antioxidants that protect your body cells from oxidation by free radicals. In fact the plant has been referred to as ‘the super antioxidant from Brazil’ by many medical writers who have recognized its right to be termed as such. To understand that, you first have to understand what an antioxidant is and how it works. The chemical names of the active substances it contains will be meaningless without that background knowledge. Oxidation occurs in your body even before you are born. What is does in general terms is to destroy your body cells, and the more it progresses the more your body is prone to cancers and cardiovascular diseases, and the more visible becomes the aging process. Chemically, oxidation is the loss of one or more electrons by an atom or molecule. Oxidation within your body is highly associated with what are known as free radicals. To explain these we have to consider the chemistry of electron pairs and free radicals, though this is not too technical so read on. Normally electrons exist in pairs of opposite spin: in simple terms each pair makes up a single negative charge. Take hydrogen: its atomic structure contains one proton and one electron. However, the hydrogen atom cannot exist by itself since the most stable configuration is that electrons exist in pairs with a net zero spin, so the hydrogen molecule consists of two hydrogen atoms with their own protons sharing an electron pair. This is true of all covalently bonded molecules. However, certain influences, such as pollution through tobacco smoke, pesticides, engine exhausts and the excess UV radiation of sunlight can cause a molecule to lose an electron. This creates what is known as a free radical: a molecule without an electrical charge but with an unpaired electron. Since the most stable configuration for it is to have a paired electron, the molecule will steal an electron from the most suitable candidate it finds. In practise this will be a body cell, and the cell that loses the electron gets destroyed causing aging of the skin and many other undesirable effects, including cancers. This stealing of an electron is chemically referred to as oxidation. Antioxidants prevent this occurring to your body cells by being reactive themselves and preferentially mopping up these free electrons. Polyphenols and anthocyanins are powerful antioxidants, and that is why the people of the Amazon rainforests have used acai not only as a food, but also for their health. It is only relatively recently that, as with many of the ancient health remedies, the scientific basis behind its use has been proved. The early Brazilian natives may not have understood biochemistry or what free radicals were, but they sure knew what was good for them. As with many other foodstuffs containing powerful antioxidants, it is likely that it was the highly colored berries that first attracted them. That does not suggest that all brightly colored foods are good for you, but the brightly colored pigments and dyestuffs contained within them also tend to act as antioxidants due the same electron configuration that provides them with their color. Many of these chemicals are also use as food dyes, and have been used so since before their chemistry and antioxidant effects were known. The color comes from the same electron activity that makes them destroy free radicals. That is why most highly colored foods contain significant quantities of phytochemicals. The deep purple color of the acai fruit led chemists to determine its content of polyphenols, such as anthocyanins, that are common in other highly colored foods such blueberries, peppers and aubergines. High concentrations of anthocyanins such as cyandin-3-glucoside and the rutinoside analogue were found, together with flavonoids such as orientin, deoxyhexose and scoparin. A total of twelve flavonoids were discovered that explains the highly antioxidant properties of the fruits. Laboratory and other tests have indicated that over 80% of the antioxidant effect of acai is due to polyphenols other than the anthocyanins. It is likely that these are the twelve flavonoids identified to date and any others that have still to be detected. However, it is not only for its antioxidant properties that acai is such a healthy fruit, since it contains many other nutritional components. It contains fatty acids, including linoleic acid, an omega-6 fatty acid and also beta-sitosterol that are believed to reduce the level of LDL cholesterol in the blood. The fruit also contains a high level of amino acids, essential for the synthesis of proteins and DNA. So what exactly does this mean for you in real terms? Antioxidants can do different things for different people, and the acai berry is said to have more than thirty times the antioxidant power of red wine. When you consider that many doctors believe one glass of red wine to provide sufficient antioxidant for the average person, you are getting a very high dose with acai berries, so what does it do for you? Due its effect in destroying the free radicals caused by pollution, acai and similar powerful sources of antioxidants are becoming increasingly important to our diets. What was a sufficient antioxidant intake even twenty years ago is not longer sufficient. Acai can help to combat early aging by reducing the rate at which your body cells are destroyed by free radicals. It also reduces the risk of cardiovascular disease, and the associated high risk of strokes or heart attacks. Acai juice itself has an unusually high fiber content, and helps maintain the health of your digestive system. An associated benefit of this is that you are less liable to contract colon cancer than if you did not consume it. Due to a reduction in the rate of destruction of body cells, including brain cells, elderly people benefit through maintenance of their brain function, and a lower likelihood of degenerating cognitive ability. It helps you to maintain concentration and memory, and can also reduce the risk of you getting cataracts. Antioxidants are also known to help maintain the immune system, and act as anti-inflammatories, and it is believed that acai juice can help to reduce the symptoms of arthritis. If you use acai berries as part of a daily diet, you should receive the benefits that it provides, although a more measured dosage in the form of a supplement will enable you to control your intake of acai, and if one thing is certain it is that you will be far healthy with a regular dose of the superantioxidant from Brazil than without.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1712) Bioflavonoids: Boost Your Brain and Circulatory Health
Date:
January 17, 2008 01:16 PM
Bioflavonoids are most commonly praised for their antioxidant properties. They were first identified in the 1930’s by Albert Szent-Gyorgyi, Ph.D., a Nobel laureate. They are thought to prevent the breakdown of vitamin C in the body, and they also boast their own antioxidant capabilities. Over 5000 different bioflavonoids have been identified in nature. They are classified into categories including flavones, anthocyanidins, flavones, flavonols, isoflavones and flavans. Science is still discovering new types and their healing properties every day. The best part about them is that they are all natural and very powerful. For example, scientists have been promoting the amazing benefits of the antioxidant found in dark chocolate. It is called epicatechin, and it is an excellent bioflavonoid for heart health. Studies show that it helps maintain healthy blood vessels. Antioxidants in dark chocolate are also believed to lower high blood pressure, according to a study published in the Aug. 27, 2003 edition of The Journal of the American Medical Association. Rutin and quecertin, both found in red grapes, are also linked with a healthier circulatory system. A study conducted at the University of Wisconsin in Madison in 1995 found that “the antioxidant and platelet inhibitory properties of other naturally occurring compounds in the wine the consumption of flavonoid-containing foods and beverages may retard atherogenesis and prevent thrombosis on a daily basis.” Translated into common terms, the researchers concluded that bioflavonoid may slow artery and vein degeneration and prevent blood clotting. The American Heart Association feels that this area of research is very promising. Their website states, “Phytochemicals are chemicals found in plants. Plant sterols, flavonoids and sulfur-containing compounds are three classes of micronutrients found in fruits and vegetables. These compounds may be important in reducing the risk of atherosclerosis, which is the buildup of fatty deposits in artery walls.” As far as healthy brain function is concerned, bioflavonoid is thought to help with microcirculation in small vessels throughout the body. You might recall seeing ginkgo biloba in the news. It has been shown to improve memory with its powerful bioflavonoid in numerous studies. What makes ginkgo especially significant is that its bioflavonoids have a stronger potency than many other bioflavonoids, and it seems to have specific benefits in the capillary beds of the brain. The National Center for Biotechnology Information recently reported the following on their website: “Flavonoids were shown to activate key enzymes in mitochondrial respiration and to protect neuronal cells by acting as antioxidants, thus breaking the vicious cycle of oxidative stress and tissue damage. Furthermore, recent data indicate a favorable effect of flavonoids on neuro-inflammatory events.” In other words, bioflavonoid is thought to help protect your brain cells from degeneration, and recent data shows that they may also reduce swelling. Researchers are eager to discover all the healing properties bioflavonoids possess. Modern medicine is now faced with an all natural group of chemicals found in plant pigments that may prove to be effective in preserving brain function and promoting cardiovascular health. This is fantastic news for people that prefer natural supplements over expensive prescription pills. Current research shows that these chemicals have significant powers for enhancing overall health. In fact, many researchers advocate including bioflavonoid supplements in your daily health maintenance plan.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1690) Natural Supplements Like Fish Oils And Phosphatidylserine Can Boost Memory
Date:
January 14, 2008 03:24 PM
We often think of our brain as being different from other organs, but the brain undergoes changes over time, just like the heart. Up until recently, brain aging and everything that goes along with it was associated with neuron failure. Actually, brain neurons do not undergo massive die-off with age. Although some neurons are lost, the brain continues to grow new ones, though at a slower pace. Decreasing cognitive function is now believed to start as early as one's late thirties, which is the result of a lowered vascular function for oxygen and nutrient supply, increased oxidative stress, and decreased production of neurotransmitters. Other issues impact memory too such as normal aging, emotional trauma, alcoholism, depression, seizures, dementias, stroke, neurodegenerative illnesses, and obesity. All of these can lead to devastating changes in mood and memory. Additionally, it is widely known that the use of cholesterol-lowering drugs can severely impact skills that involve brain functions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1688) A Periwinkle Extract Vinpocetine May Promote Cerebral Blood Flow
Date:
December 01, 2007 09:05 AM
Periwinkles form the plant genus Vinca, of which the lesser periwinkle and the greater periwinkle are the two members. They are also a form of dogbane, known for its alkaloid properties. Periwinkles are of interest to the medical profession due to their biosynthesis of a number of alkaloids that are used to protect themselves from bacteria and are also toxic to the herbivores that would otherwise eat them. Many other plants produce alkaloids, perhaps the best known being poppy, that produces the alkaloid opium that is the precursor to heroin. The alkaloids of the periwinkle, however, have a much more beneficial use for mankind in their action on certain types of cancer such as Hodgkin’s disease, and also on the flow of blood to the brain.
The components of the periwinkle include vinblastine, which is used in the treatment of Hodgkin’s lymphoma, and it is the only plant known to produce the alkaloid, although only in very small quantities after synthetic seeding. This involves introducing modified tryptamines to the plant so that they produce the desired alkaloid, although only in quantities of 0.002% of the weight of the plant. Although small, this is still less expensive that synthesizing the alkaloid in a chemical plant rather than a biological one! Chemists are now seeking more readily synthesizable alternative forms of the alkaloid that have the same effect, again using the periwinkle as a botanical chemical factory to provide them with a lead as to possible synthetic routes. However, it is for the application of another alkaloid of this amazing little plant that we are more concerned with here. In addition to vinblastine, the periwinkle produces the alkaloid vincamine, a type of tryptamine that can be extracted from the leaves of the lesser periwinkle, the Vinca minor. This periwinkle has been used through the ages as an invigorating tonic and as an astringent to treat bleeding gums and sores in the mouth. Vincamine promotes the aerobic glycolysis that is essential to cerebral health. Normal glycolysis, or the conversion of glucose to energy in the mitochondria of the cells of the body, occurs best in the absence of oxygen (anaerobic glycolysis). However, the brain produces up to and over 90% more energy through aerobic glycolysis in the presence of oxygen than through anaerobic. Hence one of the needs for such a rich supply of oxygenated blood being needed by the brain. As people grow older, or their brain tissue becomes damaged, then the supply of blood can be reduced and more and more anaerobic glycolysis is switched on. This results in an increasing loss of brain energy and hence brain function. Vincamine can reverse this effect, or at least maintain the status quo, and so enable people to maintain their brain function for longer. It is also what is known as a vasodilator, and dilates the blood vessels in the brain allowing a greater blood flow. It is known to be beneficial in relation to tasks requiring focused concentration such as mathematical problem solving, and has also been found effective in the treatment of people with poor memory. Vinpocetine (ethyl apovincaminate) is a derivative of vincamine, obtained by slightly modifying the molecule to produce a commercial form of the alkaloid. This possesses all of the beneficial effects of its precursor, including its positive effects on memory, believed to be due to the stimulation of serotonin production that improves the rate at which the brain can process information. Tinnitus, or ringing in the ears that has severely reduced the quality of life of so many people, can also be treated with vinpotecine. Its vascodilation effect is thought to be through its action as a phosphodeaterase 1 (PDE1) inhibitor that results in an improvement in the plasticity of neurons. The mechanism is complex, but the end result is an improvement in the cognitive abilities of the subject. This is supplemented by the effect of vinpocetine on the calcium levels in the blood vessels. This renders them more plastic in much the same way that some anti-hypertension treatments work to reduce blood pressure by increasing the plasticity of the blood vessels by modification of their calcium levels. It can also reduce the viscosity of the blood through its action on the “stickiness” of leucocytes and so allow the blood to run more freely through the capillaries of the brain. These effects have been demonstrated through double blind studies, and there is little doubt that vinpocetine helps to maintain a healthy cerebral circulation. So let’s have a recap on its various effects, and then finish with a summary of the conditions that the alkaloid can be used to treat or improve. The theory and biochemistry behind these effects is known, but is complex, but here are the major actions: a) It improves blood flow by modifying the calcium content of the blood vessels and so improves their elasticity, hence allowing a freer movement of blood. In effect it helps the blood vessels to dilate easier. b) It inhibits the enzyme PDE1 and by doing so helps to restore the elasticity of neurons in aging brain cells, allowing them to relax more and operate more effectively. c) It promotes aerobic glycolysis, and so the rate at which the mitochondria of brain cells produce ATP (adenosine triphosphate) that is the chemical manifestation of energy. d) It helps to maintain a good supply of glucose and oxygen in the brain to allow (c) to occur. Not all of these may be separate effects, but the outcome is an improvement in conditions such as short term memory loss, dementia and other conditions associated with a reduction in the blood supply to the brain including Menière’s syndrome and vertigo. There is also evidence that it helps with hearing problems, macular degeneration of the eye, and fatigue. It is a supplement that should be taken by the elderly to help with age-related memory problems, but has also been found to be beneficial in normal healthy people. The periwinkle extract Vinpocetine has been shown to have benefits, largely through an increase in the blood flow to the brain, and will be of use to anybody suffering from conditions that can be related to a deficiency in their cerebral blood supply.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1643) 7-Keto, The Next Dhea With No Side Effects
Date:
November 10, 2007 12:24 PM
7-Keto is a natural derivative of DHEA that is claimed to be free from many of the side-effects of regular DHEA supplements. DHEA is dehydroepiandosterone, which is the most abundantly produced of the adrenal hormones. After production in and release into the bloodstream by the adrenal glands that are situated just over the kidneys, DHEA undergoes metabolism to the male androgen hormones, and the female estrogens. As you age, the production DHEA declines, starting at about 30, with a 50% decline by time you reach 40 and almost 85% at 70. This is true of the levels of many hormones in the body, though some, like the steroidal aldosterone, remain constant throughout life. The general rate of metabolism also reduces with age resulting in an even lower conversion rate of DHEA to the male and female hormones. At the same time as this occurs, there also occurs a significant reduction in the biosynthesis of protein in the body, which results in a loss of muscle mass as you age, and also in the regeneration of bone tissue that results in what is commonly termed age-related osteoporosis. brain cells die at an increasing rate leading to many neurological conditions and the immune system is also affected negatively. Due to the concurrence of these aging effects, many scientists have related the general hormonal decline with the other effects of aging. The have asserted that if these hormones were restored, than many of the effects of aging could be delayed. Osteoporosis would be delayed due to the body’ s increased ability to restore lost bone mass, the metabolic rate would improve and fat would be burned at a faster rate and continue to build muscle, the brain would lose its functionality at a significantly lower rate and the immune system would continue to protect the body against disease. In other words we might be able to live longer, but if not that then at least the quality of life would be maintained longer as we aged. This is a very welcome and desirable situation, but the taking of hormones as supplements has long been regarded as fraught with danger due to the possibility of undesirable side effects, some of them potentially very serious. DHEA was considered as one of these hormones that could be used as a supplement to achieve positive results in reducing these age-related changes because it exhibited these effects in tests on animals. However, in order that a specific substance can be declared responsible for any metabolic improvement that involves liver biochemistry, some form of receptor has to be identified, and this failed to materialize in DHEA. There appears to be no such DHEA receptor, although that does not necessarily imply that DHEA is not responsible in some way. It might very well be a DHEA metabolite that is responsible, and that has still to be identified. It is certainly true that DHEA administered to both animal and human subjects has resulted in an increase in the testosterone and estrogen levels of the subjects. Such an increase is not desirable due to a number of potential side effects as previously inferred. These are particularly liable to occur with people who already have an adequate level of natural DHEA production within their body. The side effects include acne, irregularity in the menstrual cycle, itchy scalp, increased body odor and an excess of androgenic hormones can lead to hair loss, or male pattern baldness. Interruptions in the heart rhythm, or palpitations, are another very serious side effect of DHEA supplementation, and high doses over a long period introduce a theoretical risk of certain cancers. However, the discovery of 7-Keto, a natural derivative of DHEA claimed to be free from many of these side effects, has altered the situation. 7-Keto is a powerful antioxidant that speeds up the metabolism of fat and helps to reduce body weight. It also helps to replace lost fat with muscle mass, though it must be stated that this effect is only valid after the natural production of DHEA has slowed down. It is not a body-building supplement. It was Professor Henry Lardy, of the Department of Biochemistry at the University of Wisconsin, who tested over 150 DHEA metabolites over 10 years and identified 7-oxo-dehydroepiandrosterone as having the greatest biochemical effect without having any detectable side effects. This material was trademarked 7-KETO by the Humanetics Corporation, and one of its known effects is to burn fat quicker by stimulating thermogenesis. It had also been shown to strengthen the immune system and to improve the memory. All of this without any measurable increase in any of the sex hormones. It was released after a careful and intensive series of safety tests on both humans and animals found it safe for human consumption. It should be stressed that 7-Keto is not a hormone, and is not chemically the same as DHEA: it is a different chemical altogether that is produce when DHEA degrades in the body. Because of this it can be promoted as a non-androgenic or estrogenic form of DHEA. It is thought that all of the conditions that decline as we age that can benefit from a supplement of DHEA, will also benefit from a supplement of 7-Keto. However supplementation is only required from the ages of 25 – 30, when the natural amount of DHEA and 7-Keto in the body start to decline. It causes neither high blood pressure nor any form of cancer, and was submitted to the FDA prior to being made publicly available. It is important to stress that the substance is neither a steroid nor does it metabolize to steroidal hormones, and is also not a sex hormone. It also has no effect on the body’s sex hormones. The whole point of 7-Keto is that it has the effect of DHEA without having any connection whatsoever with steroidal hormones or any hormonal substances. It is totally innocuous and safe to use, without the risk of heart palpitations, lost hair or any of the other side effects of DHEA.
Without a doubt, 7-Keto is a DHEA substitute that has none of the side effects of its precursor. So if you are over the age of 30 and feel the need for an energy boost, give 7-keto a try.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1626) Omega-3 Relieves Depression in Some Individuals
Date:
November 02, 2007 03:27 PM
Omega-3 oils contain fatty acids that are known as essential fatty acids because they cannot be manufactured in your body but have to be taken in your diet. They provide many benefits to your body, and are also believed to relieve depression in some individuals. First, however, an overview of the more conventional benefits of omega-3 oils. Obtainable in your diet from oily fish such as mackerel, herring, salmon and the like, omega-3 fatty acids play an important part in your normal growth and development, and are also crucial to normal brain function. They can reduce inflammation and protect you from heart disease and some cancers. Studies have shown the fatty acids to be particularly concentrated in the brain and to be important for cognitive processes and memory. The effects of omega 3 fish oils on the brain are well documented, and they are known to be effective treatments in some cases of bipolar and schizophrenia. It is believed that they could also be used as a treatment in other disorders such as attention deficit disorder and dyslexia, but there is as yet no evidence that this is the case. Omega-3 fatty acids reduce the so-called ‘bad’ low density lipoprotein (LDL) cholesterol levels and increase the high density lipoproteins (HDL) that take the cholesterol back to the liver for destruction. The end result is a reduction in the cholesterol content of the blood that can be deposited on the artery walls and promote atherosclerosis. Diets high in omega-3 fatty acids appear to lower blood pressure in those suffering from hypertension, and so reduce their chances of heart attacks and strokes. Omega 3 oils are also natural inflammatories, and help prevent conditions involving inflammation such as arthritis, asthma and menstrual cramps. They appear to help the immune system to fight these conditions and reduce the inflammation and its causes. They are also important in the formation of prostaglandins that are responsible for the regulation of important functions such as blood pressure, blood clotting and immune response. They are hormone-like substances and also control the synthesis in the body of other hormones. If the balance of fatty acids in the diet is not right, then the subsequent imbalance in prostaglandin and hormone production can lead to disease. It is in its effect on depression and mood, however, that has surprised many in the medical, profession. Ethyl-eicosapentaenoate, known as ethyl EPA, is a constituent of omega-3 fish oil and many studies have demonstrated that this substance helps cases of depression and related disorders. However, are people justified in turning to ethyl EPA to help them be cured of this condition? In one study involving 20 people, six out of ten people given the supplement displayed significantly reduced symptoms of depression after four weeks. The effects were noticed as early as two weeks and many of the depression symptoms, such as worthlessness and insomnia, had improved after three weeks. This conformed with the results of many other studies that have been carried out world wide. In Scotland, a number of patients were studied who had failed to respond to traditional antidepressant drugs. Of the seventy patients involved in the trial, all of the patients who were treated with EPA displayed significant improvements in all the symptoms of their depression after four weeks whereas those with the placebo showed no improvement. Of the two main components of omega-3 fish oil, EPA and docosahexaenoic acid (DHA), only the EPA has this property, and the EPA works best alone when the DHA has been extracted. Studies and tests have indicated that the DHA appears to be important for the brain’s structure, but the EPA for its function, hence the reason for the ineffectiveness of the former in relieving depression which is a function of the brain rather connected to its structure. In fact, depressed people have been found to be deficient in EPA in comparison to those not suffering from the condition. The original idea for this originated with the late Dr. Horribin who was pioneer in researching the effects of lipids on the biochemistry of the brain as far back as the 1970s. Since then the world-wide research has confirmed his theory. However, the reason why this theory works in practice is not yet understood. It has been established that a diet rich in trans fats can unfavorably affect the hormones in the brain that stabilize mood, possibly due to the fats slowing down the system of messaging within the brain. This kind of effect can cause depression. This is likely due to the slowing down of the messages passing between the synapses. brain cells communicate by means of chemicals that cross the synapses, or small gaps between the individual cells. They are not directly connected like normal electrical circuits. It has been theorized that the EPA speeds up the passage of these messages between neurotransmitters and neuroreceptors. Other theories have also been promoted, such as that the EPA has properties of its own that cure depression by another route altogether. A possible clue could be in the findings of one study on a man aged 21 years old whose brain was scanned before and after EPA treatment. The result showed in increase in the mass of brain cells after the treatment. This was contrary to the belief that brain cells could neither be generated nor grown once a person reaches maturity. An individual suffering depression who would like to treat themselves with EPA would have to buy a lot of oily fish since high doses are needed for this level of therapy. However, it is found in high concentrations in a few supplements available on the market, and when choosing you must use the highest grade of EPA you can get, with as low a DHA content as you can find. There is little doubt now; however, that the EPA content of omega-3 relieves depression in some individuals, although more work is needed to prove without doubt that it is effective with all forms of depression.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1613) Turmeric and Alzheimer’s Disease
Date:
May 10, 2007 12:38 PM
Turmeric and Alzheimer’s Disease
In
Compare these findings to people over the age of 65 living in the
So what are people who are living in
Q. How can curry prevent these changes in the brain? Isn’t that a lot to expect from a spice?
A. Evidently, it’s not too much to expect from this spice. Curry comes from the turmeric plant – Curcuma longa is the plant’s official name. Curcumin, a plant compound in turmeric, is the source of curry’s instantly recognizable bright yellow pigment. When it comes to the scientific research of Curcuma longa, the terms curcumin and turmeric are both used. Both refer to the same thing- tumeric extract.
There have been more than 1300 studies on tumeric and its health benefits for humans. Research has shown tumeric is able to help the body get rid of cancer-causing toxins. Turmeric also blocks estrogen receptors and enzymes that promote cancer. And it’s been found to stop the growth of new blood vessels in cancerous tumors – an important factor in keeping cancer from getting larger and spreading throughout the body.
But one of turmeric’s most exciting health benefits is its ability to reduce, prevent, and stop inflammation. While inflammation is a normal and needed response to injury or disease, chronic inflammation can cause damage to tissues. And researchers are now finding inflammation plays a huge role in Alzheimer’s disease.
Q. I’ve always heard that Alzheimer’s disease was caused by complex growths in the brain called plaques and tangles. How can simple inflammation cause such a devastating disease?
A. You are right. Plaques and tangles are indeed the hallmarks of Alzheimer’s disease. But researchers looking at the brain damage caused by Alzheimer’s have always noted the presence of inflammation wherever plaques and tangles form. In the past, this inflammation was thought to be simply a consequence of Alzheimer’s disease. Now scientists believe the inflammation itself starts a chain reaction ultimately contributing to the development of Alzheimer’s disease.
` When cells in the brain are disrupted by inflammation, amyloid, and a protein normally found in the brain, beings to act chaotically. This chaos results in the creation of beta-amyloid, protein that is toxic to cells in the brain. Sticky deposits of beta0amyloid build up and collect around the cells, making dense clumps or plaques. Because the brain can’t break the plaques down and get rid of them, they stay right where they are and slowly accumulate.
Tangles result when long protein fibers that act like scaffolding for brain cells begin to twist and tangle. The cell is damaged and eventually dies. But the tangled proteins remain in the brain even after the dead neuron has been cleared away. And inflammation might be the culprit causing the long protein fibers to start tangling.
The consequence of these abnormalities of protein in the brain is more than the cell death they cause. They also act as roadblocks interfering with electrochemical messengers being shot from cell to cell. Therefore, the remaining healthy cells’ activity is diminished as well.
Research of identical twins has repeatedly shown that if one twin has Alzheimer’s disease, the other has a 60% chance of developing the disease, too. Scientists from the Karolinska Institute in
In fact, the inflammatory process might occur years before the onset of Alzheimer’s, and be the result of any number of infections people can contract. That’s why current research is searching for ways to protect brain cells from inflammation. And why some countries have low rates of Alzheimer’s disease, like
Q. Why curry? Couldn’t other lifestyle difference account for the low rates of Alzheimer’s disease in
A. That’s a good question. When researchers begin studying a disease, like Alzheimer’s, they look for trends to help them determine how and why the disease occurs. For example, we all now know the connection between cigarettes smoking and long cancer. But, it wasn’t until the 1930’s that doctors noticed the trend fro cigarette smokers to have more lung cancer than people who didn’t smoke.
So it has been with researchers studying Alzheimer’s disease. They know Alzheimer’s disease has an important connection to inflammation. They also know turmeric reduces inflammation. And when researchers noticed these trends – that people in India eat high amounts of curry from turmeric and have very little Alzheimer’s disease – they began to theorize that turmeric might be able to prevent or even treat the illness. And the research they designed around these trends has unequivocally found turmeric to be on common denominator.
Q. What have the turmeric studies shown so far?
A. Simply amazing findings are coming from curry research. Not only does turmeric slow down cancer growth, it’s also been found to correct the cystic fibrosis defect in mice, help prevent the onset of alcoholic liver disease, and may slow down other serious brain diseases like multiple sclerosis.
Researchers from the
And now the UCLA Alzheimer’s Disease Research Center (ADRC) is using turmeric in clinical trials and studying the effect of this powerful spice in patients diagnosed with this devastating disease. Clinical trials are the gold standard of medical research. But it’s rare in Alzheimer’s disease. And it’s even more rare when all-natural herbs and spices like turmeric are used in hopes the positive benefits will be discovered. The head of the UCLA’s research team was recently interviewed and stated that setting out to hopefully prove turmeric’s ability to prevent and treat Alzheimer’s disease was “tremendously exciting.”
Q. I recently read that one of the non-steroidal anti-inflammatory drugs (NSAID) was found to prevent Alzheimer’s disease. Is this true?
A. Scientists recently studied ibuprofen, one of the NSAIDs investigated for Alzheimer’s disease Prevention. Ibuprofen belongs to a family of drugs that includes naproxen, indomethacin, nabumetone, and several others. These drugs are used most often to get rid of headaches, mild arthritis, and other kinds of pain and inflammation.
In the studies, the average dose of ibuprofen was 800mg a day. Patients took the product for two years. While the results suggested that ibuprofen might reduce the risk of developing Alzheimer’s, ibuprofen’s side effects are too harmful to be a valid lifelong prevent aid treatment. Ibuprofen, like other NSAIDs, can cause gastrointestinal bleeding when used at high dosages over a long period of time. Long term use of ibuprofen can also lead to analgesic nephropathy, a kind of kidney damage caused by NSAIDs.
As we discussed earlier, turmeric appears to block and break up brain plaques that cause the disease and helps reverse some of the damage already present. Ibuprofen does not provide any protection against free radical damage. No anti-inflammatory medicine can do this.
Q. If I eat curry will I be protected against Alzheimer’s disease? There aren’t many foods or recipes I make that require curry, do I need to eat it every day? And how much do I need?
A. If you enjoy Indian cuisine, by all means, enjoy these delicious foods. You’ll benefit your brain and your appetite. But you make a good point, American meals rarely contain curry. That’s why supplements that contain extracts are suddenly quite popular. In fact, there are numerous turmeric/curcumin supplements on the market today.
But like all nutritional supplements, some turmeric supplements are superior to others. You need to read their labels to make sure the turmeric extract you are buying will provide the protection you need. Look for high-potency turmeric extract from turmeric (Curcuma longa) rhizome. And make sure the extract is standardized to contain 90% curcuminoids, the active ingredient in turmeric responsible for the positive research findings.
Conclusion
Researchers once thought that preventing for Alzheimer’s disease would elude them for decades. In fact, several scientists privately speculated the disease might never be ameliorated. They thought the origin of the disease was too complex and the symptoms of the disease were too profound.
That’s why ongoing research on turmeric is so exciting. A safe, natural, and effective way to protect against Alzheimer’s disease almost seems too good to be true. But, the nation of
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1535) Memory And Focus
Date:
May 08, 2007 02:05 PM
Memory & Focus
Some people think getting older often means getting slower. It’s true that as we age, we may find we can’t walk quite as fast, climb as many flights of stairs, or play sports as hard as we could when we were twenty. However, we k now that a healthy diet, regular exercise, and the right dietary supplements can make a huge difference in our health, strength, and mobility as we age.
This is true for our mental abilities as well. We may not think as quickly as we used to, might misplace our keys more often, and experience more “tip-of-my-tongue” word searches. These so-called “middle-aged moments” most often have minor consequences: a missed appointment or the forgotten name of an acquaintance. However, in a small number of cases, these mental slips can also be the first sign of serious diseases of aging, such as Alzheimer’s disease of other dementias.
The good news is, just like our physical health, we can improve how we function mentally. Eating healthy foods, taking the right supplements, and participating in regular mental exercise can significantly increase our mental endurance, improve our memory, and optimize our ability to focus.
In fact, groundbreaking and ongoing research has discovered that specific herbs and vitamins, particularly Ginkgo Biloba, Bacopa monnieri, folic acid, vitamins B6 and B12, and the important co-enzyme and antioxidant, alpha lipoic acid, all have powerful effects on memory and focus. These nutritional supplements have been scientifically shown to quickly reduce mild age-related memory chances, as well as greatly reducing the risk of developing more serious problems like Alzheimer’s disease, Parkinson’s disease, or other brain diseases later on in life.
Q. What is the difference between age related memory decline and dementia?
A. As we get older, our nerve cells need more time to spark and connect, slowing the process of bringing memories and events to mind. Another theory is that, as we age, we accumulate more knowledge and memories. The mind then has to sort through much more data to reference a memory. Almost everyone middle-aged and older notices this slowdown. Memory decline and problems with mental focus are a normal part of aging.
While it’s true that the older we get, our chances of developing Alzheimer’s disease increase, this illness is not a normal part of aging. Alzheimer’s is an irreversible, progressive dementia that slowly kills nerve cells in areas of the brain where memory, learning, though, and language take place. Often first appearing as people begin retirement, Alzheimer’s disease makes the “golden years” a time of loss and devastation. Memories vanish, relationships are erased, and independence is gradually lost.
After Alzheimer’s disease, the second most common cause of dementia in older people is multi-infarct dementia. Caused by a series of mini-strokes that damage or destroy brain tissue over time, multi-infarct dementia usually affects people between the ages of 60 and 75. Men are slightly more at risk. High blood pressure is the most significant risk factor for multi-infarct dementia.
Multiple sclerosis, Parkinson’s disease, strokes, Huntington’s disease, Creutzfelt-Jakob disease, and alcoholism can also cause progressive and irreversible dementia.
While normal age-related memory and focus loss may mean we can’t remember where we put our car keys, Alzheimer’s disease and other dementia may mean we can’t remember what our car keys are used for.
Q. Are any types of memory and focus loss reversible?
A. Yes. As women enter menopause, they frequently experience trouble remembering. This memory interference is caused by hormone fluctuations and can affect speech, thinking, and attention. Symptoms of menopause-related memory loss and poor focus include recognizing faces less well than in the past, missing scheduled appointments, and misplacing articles. Once a woman passes through menopause, her ability to remember and focus most often improves.
Certain medications, such as the heavily prescribed cholesterol lowering drugs called stains, can temporarily interfere with memory. Low vitamin B levels, artherosclerosis (hardening of the arteries), and thyroid disease can cause disruption of mental focus and memory loss. These problems usually resolve with treatment of the underlying disorder.
A certain type of stoke, called a transient ischemic attack (TIA) can cause memory loss that may be reversible. A TIA is a brief episode of stroke symptoms that come on quickly. Sometimes referred to as a “mini-stroke” or “warning stroke,” a TIA is caused by a temporary interruption in the blood supply to the brain. But, unlike a stroke, a TIA does not lead to permanent brain damage. While a TIA is usually short-lived, it is likely to occur again if not properly managed and can be a warning of future stroke.
Q. I seem to forget a lot of things. How can I be sure I don’t have Alzheimer’s disease or some other dementia?
A. If you, or other around you, are concerned about your memory, you should be examined by your health care practitioner. Once the cause of your memory and focus problem is diagnosed, treatment can begin. All causes of memory loss and mental focus disruption can be treated, even Alzheimer’s disease. While presently irreversible dementias cannot be cured, the progression of the disease may be slowed, and in some cases, stopped..
Research on memory loss and mental focus disruption has increased dramatically in the past few years. Discoveries regarding Alzheimer’s disease and other dementias, as well as age-related loss of memory and focus have recently been made. Most importantly, many new treatment options, including the use of nutritional supplements, have been developed.
Q. How can nutritional supplements improve memory and focus?
A. Several herbs and vitamins have been demonstrated to improve memory and mental focus. While some nutritional supplements work now to improve memory and focus, others work to prevent problems we might develop later.
One of the most researched herbs, Ginkgo biloba, has been found to be effective in improving currently experienced memory and focus loss; in other words, problems we are having now. Ginkgo has been studied in individuals who have age-related memory loss, as well as in those with Alzheimer’s disease and other dementias. It seems that ginkgo can improve many brain functions, such as speeding up memory recall, protecting brain cells from chemical changes and free radical damage, improving blood flow to the brain, and helping nerve cells communicate with each other better.
Several studies examined ginkgo’s effect in healthy people who were experiencing normal age-related memory and focus problems. They determined that ginkgo improved memory, attention, and clarity of thinking. Ginkgo can also help restore memories that may be lost in TIAs, those mini-strokes that were discussed earlier.
In studies of individuals with Alzheimer’s disease, the results showed that ginkgo slowed down the disease in those severely afflicted and actually improved those with very mild or moderate disease. In one of these studies, ginkgo was compared to four prescription cholinesterase inhibitors, medications commonly used to treat individuals with Alzheimer’s disease. Using written mental tests, the researchers found that ginkgo worked just as effectively as the prescription drugs. While those taking one of the cholinesterase inhibitors dropped out of the study because of disturbing side effects, ginkgo had no side effects and improved symptoms equally as well.
Q. Hoe does Bacopa monnieri help memory and focus?
A. Like ginkgo, bacopa works on the memory and focus problems we are experiencing now. Bacopa grows in
Q. How does alpha lipoic acid help memory and focus?
A. Alpha lipoic acid (
Researchers have discovered unmistakable free radical damage in Alzheimer’s disease. Accordingly,
In a recent study, people with Alzheimer’s disease were given tests that measured through and memory. They were then given
Q. How do vitamins B12 and B6 help memory and focus?
A. Vitamin B6 is an essential nutrient in the regulation of nerve transmissions. It is required by the nervous system for normal brain function, and it may also help with mood.
Like
Researchers have learned that people with Alzheimer’s and other dementias (including Parkinson’s disease) have elevated homocysteine levels. IN fact, t he amount of homocysteine in the blood corresponds to the severity of the disease. Most people with a high homocysteine level don’t have enough folate, vitamin B5 or vitamin B12 in their diet. Replacing these vitamins helps return the homocysteine level to normal.
Reducing homocysteine levels may prevent the occurrence of Alzheimer’s disease, or other brain diseases, and improve the symptoms of those already afflicted.
Q. What about folic acid?
A. Folic acid has long been recognized as a vital nutrient for the brain and spinal cord. Recent research has demonstrated that folic acid has significant importance in Alzheimer’s disease.
An ongoing study of Alzheimer’s disease that began in 1986 has been studying 678 members of the School Sisters of Notre Dame in the hopes of learning how the disease develops, how it might be prevented, and how to treat it. Data collected in the study includes biographies the sisters wrote upon entrance to the order, blood samples from the sisters while they are living, and information gained from the voluntary donation of their brains after death.
Aptly named the “Nun Study,” ground breaking discoveries have already been made. It seems that diet and nutrition have a dramatic influence in the development of Alzheimer’s disease. Sisters who had high levels of folic acid showed little evidence of Alzheimer’s-type damage in their brains after death. And, those nuns who had Alzheimer’s disease in spite of high folic acid levels had profoundly less brain damage from the disease. In fact, some sisters who had no outward evidence of Alzheimer’s disease while they were living had surprisingly extensive damage in their brains after death.
Q. Besides taking ginkgo, bacopa, B vitamins, folic acid, and ALA, is there other things I can do to prevent Alzheimer’s disease?
A. You may not know if you have a serious B-vitamin deficiency. Routine lab work does not measure the amount of B vitamins in your blood. You might want to ask your health care practitioner to have your B vitamin level in your blood measured, especially if you are having memory and focus problems. Keep in mind that this type of lab work is fairly expensive, however.
Supplements do not replace the need for a healthy diet, especially a diet with high levels of fruits, vegetables, whole grains and omega-3 fatty acids. Keeping your body healthy helps keep your brain healthy as well.
It also seems that the use-it-or-lose-it theory applies to our brain as well as our body. Research has shown that people who seek opportunities to keep mentally active, such as reading books, newspapers, and magazines, solving crossword puzzles, playing card games, and visiting museums, lower their risk of Alzheimer’s disease.
Conclusion
Dealing with age-related memory loss may be both frustrating and frightening. As the population of
In fact, more and more research shows prevention of Alzheimer’s disease and other dementias is a reality. And age-related memory loss can successfully be improved as well. Taking the scientifically validated nutritional supplements ginkgo, bacopa, vitamins B6 and B12, folic acid, and
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1533) CoQ10 for Heart Health
Date:
March 28, 2007 12:39 PM
CoQ10 for Heart Health
More than 40% of all deaths in the
One of the most – if not the most – important things people can do to improve their overall health and life expectancy is to improve their heart health. Diet, exercise, and the wise use of dietary supplements can improve heart health dramatically. One dietary supplement that’s extremely beneficial to heart health is coenzyme Q10 (CoQ10).
Q. What is CoQ10?
A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitous and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all energy-requiring processes in the body. Although COQ10 is produced by the body and exists in some dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol-lowering prescription drugs known as “statin,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.
Q. For what health conditions is CoQ10 used?
A. CoQ10 is beneficial in treating and preventing CVD and conditions such as high blood pressure, atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease.
Q. Why is CoQ10 especially important to heart health?
A. The heart is one of the most metabolically active tissues in the body. In the average person, the heart propels 2,000 gallons of blood through 65,000 miles of blood vessls by beating 100,000 times each day. Thus, it requires large amounts of uninterrupted energy. Heart cells have a greater number of mitochondria, and subsequently, more CoQ10 than any other type of cell. Each heart cell can have thousands of mitochondria to meet these energy demands.
Mitochondria are highly specialized structures within each cell and are often referred to as cell powerhouses. These tiny energy-produces produce 95% of the energy the body requires. The number of mitochondria in a cell depends on its function and energy needs. A cell’s ATP production is dependent on adequate amounts of CoQ10.
Heart disease patients are commonly CoQ10 deficient. Correcting such deficiencies often can produce amazing results. The presence of supplemental CoQ10 is a key to the heart’s optimum performance.
In people who have had a heart attack (myocardial infarction), CoQ10 assists in repairing the heart muscle and restoring heart function. This is due to increased ATP production.
Q. What studies support this fact?
A. A 1998 study found CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. The study focused on patients admitted to the hospital with an acute myocardial infarction (AMI) diagnosis. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.
In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking one to three antihypertensive drugs at an average of 4.4 months after starting CoQ10. Only 3% of patients required the addition of one antihypertensive drug. The 9.4% of patients who have echo cardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.
Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the
Q. I’ve heard that CoQ10 can also help people who have neurological diseases. Is this true?
A. Yes, it is. CoQ10 has been studied for its ability to improve the health of individuals with amotrophic lateral sclerosis (ALS), Parkinson’s disease, and Huntington’s disease. A recently completed study sponsored by the National Institutes of Health showed that CoQ10 caused a slowing of the progression of Huntington’s disease, a devastating and degenerative disease that is always fatal. In fact, no other medication, drug, or nutritional supplemental has ever been shown to cause a decline in the progression of this terrible disease.
The study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable. The 15% slowing of decline means that CoQ10 can result in about one more year of independence for HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.
Because of these impressive results with HD, researchers are hopeful that the studies of CoQ10 in those with ALS and Parkinson’s disease will similarly have a positive effect on the symptoms and/or progression of these neurological disorders, too.
Q. Why is it crucial for a CoQ10 supplement to cross the blood-brain barrier?
A. The brains’ blood vessels are composed of cells with extremely tight junctions. These junctions form the blood-brain barrier, which restricts what can pass from the bloodstream into the brain. While this barrier protects the brain, it can be a significant obstacle to central nervous system therapy. To leave the bloodstream and reach the brain cells, a substance must pass through the tightly connected cells of the capillary walls. Only substances with unique solubilities or those with a transport system can cross the blood-brain barrier to a significant degree. As a result, crossing the blood-brain barrier presents a significant challenge to supporting neurological health.
While most CoQ10 supplements enter the bloodstream and increase blood serum levels, only special forms of CoQ10 have been shown to cross the blood-brain barrier. For CoQ10 to enter the mitochondria within the brain, CoQ10 must first cross the blood-brain barrier to produce significant neurosupportive clinical results.
Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?
A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.
Q. Are all CoQ10 supplements created equal? Doesn’t CoQ10 just have to get into the bloodstream to be effective?
A. There are some important distinctions among CoQ10 products, as they vary greatly in quality and absorbability. It’s crucial to find a CoQ10 product that’s:
1. Scientifically shown to absorb through the digestive tract, cross cellular membranes, and increase mitochondrial levels of CoQ10. Chewable forms of CoQ10 provide rapid bioavailability and absorption. Serum level determination of CoQ10 in the bloodstream is not necessarily the most important measure of efficacy. For a CoQ10 supplement to be fully effective, it must cross the cellular barrier and raise intracellular CoQ10 levels. A key indicator of effective CoQ10 supplementation is its presence in cell mitochondria.
2. The natural form of CoQ10. The natural process uses living organisms. CoQ10 also can be synthesized by a chemical process, which produces a distinctly different product that contains chemical compounds not found in the natural form.
3. Formulated with ingredients that provide the transport system CoQ10 needs to cross cellular membranes and the blood-brain barrier. Not all forms of CoQ10 have been scientifically proven to cross cell membranes and the blood-brain barrier. Some prestigious groups that have investigated this issue include researchers at
4. Studied by respected organizations, with research published in peer-reviewed journals by reputable scientists.
Q. How much CoQ10 should I take?
A. Take 100 to 200 mg of CoQ10 daily, depending on your family history of heart disease and personal heart disease experience.
CoQ10’s safety has been evaluated. Dosages in studies have ranged from 100 mg to 1,200 mg per day. To date, no toxicities have been reported. Occasional mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect.
Q. What are some other heart-friendly supplements?
A. CoQ10 is an excellent supplement for overall cardiovascular health, as in L-carnitine. L-carnitine is the naturally occurring form of carnitine that’s found in food and synthesized in the body. Much of the body’s L-carnitine is found in the heart and skeletal muscle, tissues that rely on fatty acid oxidation for most of their energy. Nearly 70% of the energy needed for heart function is derived from fatty acid breakdown. Proper L-carnitine supplementation transports fatty acids into cell mitochondria, where it’s burned for energy. L-carnitine is an excellent addition to CoQ10, especially for people with heart disease, and has been shown to improve many symptoms associated with CVD. In one study, people who had experienced one heart attack received either L-carnitine or placebo. The L-carnitine group had a statistically significant reduction in second heart attacks, and improved overall survival.
Q. What supplements support healthy blood pressure and cholesterol?
A. In addition to maintaining overall cardiovascular health, it’s also important to address your essential fats/lipids levels and healthy circulation/blood pressure. Fish oil supplements can significantly reduce blood pressure, cholesterol, and homocysteine levels. Choose a supplement that’s a rich source of EPA and DHA, omega-3 fatty acids naturally obtainable in fish oil. Find a product that’s been clinically studied and purified to ensure it contains the beneficial active constituents of the whole oil, while removing any dioxins, DDT, PCBs, or heavy metals, toxins present in some commercial fish oil preparations. An enteric-coated garlic product that provides a minimum of 5,000 mcg of beneficial allicin supports healthy blood pressure and circulation. And magnesium, niacin, vitamin E, folic acid, hawthorn extract, and L-cysteine provide overall nutritional support to the heart and vascular system.
Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological disease, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagined. The more we study this naturally occurring compound, the more benefits we find.
The key to this supplement is the manufacturing quality. For safety and overall effectiveness, use a CoQ10 product that’s supported by product-specific research from reputable institutions. Choose tested products from a well-respected company to increase your potential to achieve and maintain heart and blood vessel health.
Supplementation with clinically studied products can have a major impact on your heart’s health and strength. However, no supplement replaces the need to eat a healthful diet low in refined foods (especially sugar), and saturated fats, and to exercise your most important muscle – your heart – on a regular basis.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1501) Neurological Health and CoQ10
Date:
February 25, 2007 12:06 PM
Between 1946 and 1965, 78 million Americans were born, creating the largest number of children in U.S. history. This Baby Boom generation has greatly influenced the makeup of American society and undoubtedly w ill continue to do so. Thanks to good nutrition and health care, Baby Boomers are aging well and have an excellent life expectancy. For the first time in history, we have more people turning 60 every day, and record numbers of adults reaching their seventh decade. As a result, neurological diseases associated with aging, such as Parkinson’s disease, are becoming major health care concerns. The good news is CoQ10 has applications for neurological diseases, in addition to its better known use for cardiovascular diseases. Q. What is CoQ10? A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone (existing everywhere there is human life). CoQ10 is vital to the production of adenosine triphosphate (ATP). ATP is the energy-rich compound used for all energy-requiring processes in the body. Q. Isn’t CoQ10 a supplement for heart health? A. Yes, it is. Because the heart requires lots of ATP to meet its high energy needs, CoQ10’s function in heart health is well understood. Numerous clinical studies have demonstrated that when individuals with heart disease take CoQ10, their symptoms improve, sometimes quite dramatically. Supplemental CoQ10 improves the heart’s pumping ability, improves blood circulation, increases tolerance to exercise, and improves the heart’s muscle tone. CoQ10 also is a powerful antioxidant and protects heart tissue from free-radical damage. Q. How does CoQ10 affect brain health? A. CoQ10 works in the brain the same way it works elsewhere in the body: it’s essential to ATP production. Nearly all human cells contain tiny structures called mitochondria. Mitochondria are referred to as cell powerhouses because they produce cellular energy. Depending on what each cell’s job is. There can be several thousand mitochondria in one cell. If a cell needs a lot of energy, it will have more mitochondria. This explains why heart cells contain so many mitochondria; the continual pumping of blood requires continual ATP production. The brain also requires huge amounts of uninterrupted energy to regulate, integrate, and coordinate ongoing nervous system transmissions. To meet this need, ATP production within the mitochondria of brain cells is vital. Since CoQ10 exerts such a powerful influence on heart cells in ATP production, it was a natural progression for scientists to wonder how it affects brain cells. Brain and nervous system research led to the conclusion that the same intracellular principles apply. CoQ10 is produced in the body to assist in ATP production. Without it, ATP cannot be produced. The most important discovery regarding CoQ10 and the brain is that CoQ10, when formulated with certain ingredients, can cross the blood-brain barrier and enter the brain’s mitochondria. If large amounts of CoQ10 can get into the brain cell’s mitochondria, its ability to make ATP is greatly enhanced. Q. What is the blood-brain barrier and why is it important? A. The blood-brain barrier is a unique anatomical structure. The cells that make up the blood vessels that provide blood to the brain are extremely close together. This greatly restricts what can leave the bloodstream and enter the brain. While the blood-brain barrier protects the brain and spinal cord from potentially toxic substances, it also can be a significant obstacle to therapy of central nervous system disorders. Only substances with certain solubilities or those that have a transport system can cross the blood-brain barrier to a significant degree. Obtaining optimal absorption of CoQ10 is difficult. The CoQ10 molecule is large and inflexible. The easiest and least expensive way to increase absorption levels is with the use of harsh solvents such as propylene glycol. However, at higher doses, these types of chemicals are considered dangerous (neurotoxic) to the person with a serious neurodegenerative disease. It is more difficult, as well as more expensive (considering raw materials, research, and proper manufacturing methods) to promote absorption with less harmful alternatives. However, reputable companies ensure that their products are safe for all their customers. Look for CoQ10 products formulated with vitamin E and other safe ingredients such as Micosolle. Nearly all CoQ10 supplements enter the bloodstream. But, only CoQ10 supplements with special formulations have been scientifically shown to enter the mitochondria and cross the blood-brain barrier. Q. If CoQ10 is made in the body, why take supplements? A. While CoQ10 is synthesized in the body, these levels may be insufficient to meet the body’s requirements. Researchers have discovered CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. They also have determined some medications significantly reduce CoQ10 levels in the body. Although CoQ10 exists in some dietary sources, it may not be realistic to obtain CoQ10 through food alone. For example, it would take approximately 3 pounds of sardines, 7 pounds of beef, or 8 pounds of peanuts to equal 100 mg of supplemental CoQ10. Q. How does CoQ10 help people with Parkinson’s disease? A. CoQ10 seems to have several beneficial actions in the illness. Researchers have looked at mitochondria in brain cells and determined people with Parkinson’s disease have reduced activity of Complex I in the electron transport chain. Recent research has proposed the reduced activity of Complex I interferes with the brain-signaling chemical dopamine. Stored and newly synthesized dopamine is depleted. The dopamine depletion causes nerve cell degeneration. A recent clinical study involved 80 patients with Parkinson’s disease (both men and women). The researchers first evaluated all the participants to establish scores for basic motor skills (measuring the ability to control physical movements such as walking), mental status (whether the person was depressed or experiencing memory loss) and the activities of daily living (whether the person was experiencing difficulty with handwriting, dressing themselves, using utensils such as knives and forks, and so on). This scale is known as the Unified Parkinson’s Disease Rating Scale (UPDRS). This process is known as establishing “baseline values,” that is, the condition of the patient before receiving any treatment. Participants were divided into 4 groups. Each group received either 300 mg, 600 mg, or 1200 mg of the special form of CoQ10, or a placebo. The researchers observed the participants for 16 months. The results of the study showed that all the participants who received CoQ10 had smaller declines in function compared to the placebo group, but the smallest decline was experienced by the group taking the highest amount of the special form of CoQ10. The most significant results were noted specifically in the activities of daily living scores by the people taking 1200 mg of CoQ10 daily. These people retained better ability to feed and dress themselves, speak, walk, and bathe or shower by themselves. They maintained greater independence for a longer time. Parkinson’s disease, as with other neurodegenerative diseases, robs the sufferer of their ability to control the movements of their own body and care for themselves. Supplementation with CoQ10, while not a cure, is the first intervention that showed a slowing in the progressive deterioration of the function associated with this disease. Q. What were the results of clinical research on Huntington’s Disease? A. A randomized, double-blind, placebo controlled study respected type of study, was conducted at the University of Rochester. All of the 347 Huntington’s disease (HD) patients were experiencing some HD symptoms, but were still in the early stages of the disease. The patients (who did not know which drug they were receiving) were randomly assigned to four different treatment groups: 25 percent received Remacemide, 25 percent received CoQ10, 25 percent received both, and 25 percent received a placebo, or sugar pill. The researchers, who also did not know which patients got which drug, watched and recorded their progress for two and one-half years. Remacemide is a new drug made by Astra Seneca that blocks the neurotransmitter glutamate in the brain, that has long been suspected of contributing to the death of brain cells in Huntington’s disease. Unfortunately, in the CARE-HD study, Remacemide had no effect on the progression of the disease in patients in the early stages. However, the individuals who received 600 mg of CoQ10 per day experienced some slowing of the disease progression. They were able to manage daily activities, such as meal preparation, housekeeping tasks, and personal care longer than those not on CoQ10. They were also able to focus their attention better and were less depressed and irritable. The portion of the studied patients receiving 600 mg of CoQ10 per day experienced a 15 percent decline in the progression of HD. According to the researchers conducting the study, a 15 percent decline in the progression of HD would roughly translate into approximately one more year of independence for patients. This is the very first study from more than a dozen Huntington’s disease patient trails that showed any modification of the course of the illness. Of note, the effects of the CoQ10 had not abated at the end of the research study. That is, the benefit of using CoQ10, 600 mg per day, was still increasing; this suggests that the longer a patient supplements with CoQ10, the greater the decline in the progression of HD. The next phase of the CARE-HD research will test a higher dose of CoQ10 (1200 mg or more per day), with more patients (over 1000), for a longer period of time (approximately 5 years). This study should improve our understanding of the optimal dose and the total achievable decline in the progression of HD. The CoQ10 product used in the CARE-HD study was designated an Orphan Drug by the FDA. The product utilizes a proprietary, patent-pending delivery mechanism, which is proven to be safe and tolerable at high doses for people suffering from neurodegenerative diseases, substantially improving brain tissue levels of CoQ10. Q. What other diseases could benefit from CoQ10 supplementation? A. Studies show CoQ10 levels are greatly reduced in Alzheimer’s patients. Mitochondrial abnormalities also are noted; however, research has yet to determine how or why this occurs. Some scientists believe damage to mitochondria is an early feature of the disease. Free-radical damage also is a feature of Alzheimer’s. In a study of 27 Alzheimer’s patients, subjects were given 60 mg of CoQ10, 150 mg of iron, and 180 mg of vitamin B6 daily. Each patient’s mitochondria activity was effectively activated. All patients continued to experience gradual decline. However, researchers believed that with this combination, the progression was much slower and allowed the patients to experience 1 to 2 years of extended good health. ALS (also known as Lou Gehrig’s disease) is a progressive, fatal, neurological disease. It occurs when the nerve cells in the brain that control voluntary movement gradually degenerate. Investigation of CoQ10 in individuals with ALS is just beginning. Researchers at the Eleanor and Lou Gehrig ALS Center at Columbia University recently conducted a small clinical pilot trial of CoQ10 in ALS. The study was an open label study, which meant that everyone enrolled received CoQ10, 400 mg three times per day. Of the 16 patients originally enrolled, nine patients completed the study. Six of these nine patients experienced some benefits. The patients declined from 0 – 25 percent in functional scores, 6 percent in strength, and 10 percent in breathing ability. These scores reflect a positive trend compared to the 50 percent decline that is seen in the natural history of ALS over the same period of time (5 to 9 months). Citing the need to conduct more studies of the effectiveness of CoQ10 for people with ALS is rapidly and efficiently as possible to get answers to patients and clinicians, another clinical trial is currently underway at the Gehrig ALS Center. This is a pilot study to determine if CoQ10 has short-term effects on motor nerves in the brain using magnetic resonance spectroscopy (MRS). The researchers are going to try to “see” if CoQ10 can change the chemical sin the brain’s upper motor nerves of people with ALS, an important next step of the investigation. Q. Can taking CoQ10 prevent neurodegenerative disease? A. To date, there have been no studies or research examining whether CoQ10 can prevent these diseases. Alzheimer’s disease prevention is being clinically investigated. Researchers have determined that people who take certain anti-inflammatory medications seem less likely to develop the illness. A large, multi-centered trial is studying this connection. Q. How much CoQ10 should I take? A. Depending on your family history of neurological disease and your disease experience, studies show benefits at doses of 100 to 200 mg of CoQ10 daily. Some studies used doses of up to 1,200 mg per day. CoQ10’s safety has been evaluated. To date, no toxicities have been reported. Mild stomach upset may occur. Taking CoQ10 with meals usually alleviates this rare effect. Q. What should I look for in a CoQ10 supplement? A. Use products which have a strong clinical research track record, supported by product-specific research from reputable institutions, and have been proven to be safe, tolerable and effective in treatment of neurodegenerative diseases. The CoQ10 product you choose should be proven to: be absorbed, enter the blood stream, cross the blood brain barrier and increase mitochondrial levels of CoQ10. If the product you are considering does not have evidence to support these points, keep looking. Once you have found a candidate, examine the product’s safety and efficacy record for neurodegenerative diseases- if the product has not been proven to be safe and effective, keep looking. Good products exist; however, caveat emptor. Conclusion CoQ10 supplementation for people with neurodegenerative diseases is supported by contemporary clinical research. CoQ10 is certainly not the only answer to the complex issues of management and treatment of these types of diseases. However, research indicates that it is a bigger piece of the puzzle than physicians and scientists ever imagined. As we continue to study this naturally occurring compound, we are finding more and more benefits to the body. All CoQ10 is not created equal. For safety and overall effectiveness, use a CoQ10 product that is supported by product-specific research from reputable institution, which is proven to be safe, tolerable and effective at high doses; deviating from this set of criteria may do more harm than good for people with these serious illnesses. Choose clinically tested products from a well-respected company and increase the potential to achieve and maintain brain and neurological health.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1459) Fruit and Vegetable Lightning drink mixes from Natures Plus
Date:
February 06, 2007 02:41 PM
Enjoy the Rainbow – the Color Wheel of Fruits and Vegetables
We’ve all heard the statistics, and have probably seen the signs in the produce section of our favorite grocery store: eating 5 servings of fruits and veggies a day is important,
Chances are also pretty good that we’ve also seen the newest food pyramid, encouraging Americans to “eat a rainbow of frits and vegetables.” That is, choose from the rich variety of colors for the best all-around health benefits.
In this Ask the Doctor, we’re going to look at the unique health components of different colored fruits and vegetables, and why they’re so important. Plus, we’ll learn about supplemental options, like fruit and vegetable drink mixes, for those days when our diets just aren’t that great.
Q. What’s the big deal about fruits and vegetables?
A. Well, for the main reason that they are whole foods – created by nature (or at least generations of farming) and are rich in a variety of nutrients. Processed foods can’t match the health benefits of strawberries or broccoli – items that have fiber, vitamins, and enzymes built right in.
Q. What does “eating a rainbow” of fruits and vegetables really mean?
A. This is simply an easy way of remembering to get as much color variety in your diet as possible to maximize your intake of a broad range of nutrients. The colors of fruits and vegetables are often a tangible clue to the unique vitamins and other healthy substances they contain. Getting a variety of colors, therefore, means getting a variety of the essential nutrients your body needs to stay healthy and strong.
Enjoying the Rainbow: Fruit and Vegetable Benefits:
Q. Can you tell me a little more about the healthy components of fruits and vegetables?
Let’s take a look at some of the most well-studied and important nutrients:
Quercetin is found in apples, onions and citrus fruits (also is hawthorn and other berries and apple-related fruits usually used in traditional herbal remedies and modern supplements). It prevents LSL cholesterol oxidation and helps the body cope with allergens and other lung and breathing problems.
Clinical studies show that quercetin’s main points of absorption in the body appear to be in the small intestine – about 50%. The rest – at least 47% is metabolized by the colonic micro flora – the beneficial bacteria such as Lactobacillus acidophilus and Bifidobacterium longum. You may consider adding these beneficial bacteria (found in yogurt) either through the diet or a supplemental form.
Ellagic Acid is a component of ellagitannins – dietary polyphenols with antioxidant (and possibly anticancer) properties. Polyphenols are the basic building blocks of many plant-based antioxidants. More complex phenolic compounds, such as flavonoids are created from these molecules.
Ellagic acid is found in many fruits and foods, namely raspberries, strawberries, pomegranates, and walnuts. Clinical studies suggest that ellagitannins and ellagic acid act as antioxidants and anticarcinogens in the gastrointestinal tract.
Ellagitannins are durable antioxidants, and happily, they do not appear to be diminished by processing, like freezing. This means the benefits are still strong, even in frozen packs of raspberries or strawberries, or some of the better multi-ingredient supplement drink mixes.
In scientific studies, ellagic acid also showed an anti-proliferative effect on cancer cells, decreasing their ATP (adenosine triphosphate) production. ATP is the molecule that provides the primary energy source for the cells in our bodies. In a sense, ellagic acid seems to deprive cancer cells of their fuel.
Beta-Carotene: Probably the best-known of the carotenoids, beta-carotene is converted by the body into vitamin A. Many vegetables, especially orange and yellow varieties, are rich in this nutrient. Think summer squash, yams and of course, carrots.
Beta-carotene has long been associated with better eyesight, but it has other benefits, too. In a scientific study, beta-carotene decreased cholesterol levels in the liver by 44% and reduces liver triglycerides by 40%.
Lycopene is a carotenoid mostly found in tomatoes, but also in smaller amounts in watermelon and other fruits. Clinical studies have shown that lycopene consumption may decrease the risk of prostate cancer. In fact, high intakes of lycopene are associated with a 30% to 40% reduced risk. And, as good as beta-carotene is, its cousin, lycopene, seems to be an even stronger nutrient, protecting not just against prostate cancer, but heart disease as well.
Lutein is found in many fruits and vegetables, including blueberries and members of the squash family. Lutein is important for healthy eyes, and in fact it is found in high concentrations naturally in the macular region of the retina – where we see fine detail. It is one of the only carotenoids, along with its close sibling zeaxanthin, that is found in the macula and lens of the eye.
Lutein also supports your heart, too. In a scientific study, lutein reduced atherosclerotic lesion size by 43%. In other words, high intakes of lutein may actually help prevent coronary artery disease!
Interestingly, as is the case with lycopene, cooking or processing foods with lutein may actually make it more easily absorbed.
In clinical studies, men with high intakes of lutein (and its close cousin, zeaxanthin, found in broccoli and spinach) had a 19% lower risk of cataract, and women had a 22% decreased risk, compared to those whose lutein intakes were much lower.
Vitamin C: One of the best-known nutrients out there, vitamin C keeps our immune system strong; speeds wound healing, and promote strong muscles and joints. A free-radical fighter, vitamin C prevents oxidative damage to tissues, builds strength in collagen and connective tissue, and even reduces joint pain.
Sources of vitamin C are scattered throughout the spectrum of fruits and vegetables.
Potassium: Most Americans are deficient in potassium. For the most part, it’s hard to get too much of this valuable mineral. Potassium does great things for our hearts. Higher intakes of dietary potassium from fruits and vegetables have been found in clinical research to lower blood pressure in only 4 weeks.
Many researchers believe that the typical American diet has led to a state of chronic, low-grade acidosis – too much acid in the body. Potassium helps change pH balance to a more alkaline environment in the body and increases bone density.
This was proven in the long-running Framingham Heart Study which showed that dietary potassium, (along with magnesium and fruit and vegetable intake) provided greater bone density in older individuals.
Fiber is another food component many just don’t get enough of – especially if they’re eating a “typical American diet.” Fruits, vegetables and whole grains are excellent sources of fiber. However, fiber from a good fruits and vegetable drink mix should be derived from inulin and chicory root. This soluble fiber source not only adds to the overall amount of fiber you need (25 to 38 grams a day), but also provides a nice “nesting ground” for the beneficial bacteria that populate the intestines. And, even though some fiber has a bad rap for inhibiting mineral absorption, inulin and chicory root are “bone building” fibers – they actually help the body absorb calcium.
Flavonoids are an overarching term that encompasses flavonols, anthocyanidins, and flavones, isoflavones, proanthocyanidins, Quercetin and more. They are almost everywhere: in fruits, vegetables, grains, herbs, nuts and seeds – even in the coffee, wine and tea we drink. Flavonoids are responsible for the colors in the skins of fruits and the leaves of trees and other plants.
Flavonoids have many health benefits. They can help stop the growth of tumor cells and are potent antioxidants. Additionally, flavonoids have also been studied for their ability to reduce inflammation.
Anthocyanins: High on the list of important “visible” nutrients are anthocyanins. They color fruits and vegetables blue and red.
Anthocyanins are members of this extended family of nutmeats, the flavonoids. Typically found in high amounts in berries, anthocyanins are readily absorbed in the stomach and small intestine.
As antioxidants, anthocyanins dive deep into cell membranes, protecting them from damage. IT may be one reason why the anthocyanins from blueberries are considered such an important component in battling neuronal decline, like Alzheimer’s. Blackberries, raspberries, and strawberries are also excellent sources of this flavonoids group.
SDG lignans, (short for secoisolariciresinol diglucoside) are polyphenolic components of flaxseed, pumpkin and other herbal sources. Much of the recent research surrounding lignans has focused on flaxseed. In scientific and clinical studies, lignans from flaxseed support hormonal balance and may have cancer-preventing abilities. In fact, in one study, flaxseed lignans reduced metastatic lung tumor by 82% compared to controls.
The lignans in pumpkin seed, also considered a major source, target 5-alpha reductase activity.
This enzyme catalyzes the conversion of testosterone into the more potent dihydrotestosterone (DHT). DHT, like testosterone, is a steroid hormone or androgen. Androgens are responsible for the development and maintenance of masculine sex characteristics in both men and women. Excess levels of DHT can cause serious problems with prostate or bladder health. That’s why modulation of the 5-alpha reductase enzyme is so important – it helps maintain healthy testosterone and DHT levels. By balancing the levels of these key hormones, pumpkin seed lignans provide protection for prostate and bladder cells.
In addition, pumpkin seed has been shown to modulate the enzyme aromatase. Aromatase is present in the estrogen-producing cells of the adrenal glands, ovaries, testicles, adipose tissue, and brain. Aromatase converts testosterone, an androgen, into estradiol, and estrogen.
Inhibition of the aromatase conversion can help maintain a balance of healthy testosterone levels in women, which has been shown to strengthen pelvic muscles and reduce incidence of incontinence.
In fact, a clinical study, involving a pumpkin extract in conjunction with soy, resulted in significant support for bladder health. After two weeks of supplementation, 23 of the 39 postmenopausal women enrolled in the study showed great improvement in urinary frequency and sleep. By the end of the six week study, 74.4 percent of participants found pumpkin extract safely and significantly improved “nocturnia,” that is, the need to urinate frequently at night. For individuals with 2 to 4 episodes of nocturnia prior to the stud, and 81.8% improvement was seen – also showing great improvement in sleep quality. After all, if you don’t have to wake up every couple of hours to go to the bathroom you’re bound to get better sleep.
Beta glucan: Mushrooms are intense immune-boosting powerhouses due to their beta-glucan content. Three well-studied power-house mushrooms that contribute beta glucan to the diet include maitake, reishi and shiitake.
The most significant constituents of mushrooms are long chain polysaccharides (molecules formed from many sugar units) known as beta-glucan. These huge molecules act as immunoregualtors in the human body, helping to stabilize and balance the immune system.
This includes specific support of white blood cells, or lymphocytes, the primary cells of the immune system. Lymphocytes fall broadly into three categories: T cells, B cells, and natural killer (NK) cells.
In one clinical study, 165 patients with various types of advanced cancer were given maitake mushroom compounds alone or with chemotherapy. Cancer regression or significant symptom improvement was observed in 58% of liver cancer patients, and 62% of lung cancer patients. Plus, when maitake was taken in addition to chemotherapy, the immune cell activities were enhanced 1.2 to 1.4 times, compared with chemotherapy alone.
In another clinical study, researchers determined that Reishi increased the number of cancer killing white blood cells and made them more deadly to cancer cells.
And, in a scientific study of human breast cancer and myeloma cancer and myeloma cancer cell lines, shiitake compounds provided a 51% antiproliferative effect on the cells – inducing “apoptosis’ – the programmed cell death that should occur naturally.
While beta-glucan are distributed throughout the mushroom body, the beta-glucan concentrations are significantly higher in the mycelium – the interwoven fibers or filaments that make up the “feeding structure” of the mushroom.
Bioflavonoids are commonly found in bright yellow citrus fruits, including lemons, limes and oranges. They are responsible for the bright pigment found in the skin of the fruit, and are considered a “companion” to vitamin C, seeming to extend the value of the nutrient within the body.
Hesperidin is just one of the valuable bioflavonoids found in citrus. Hesperidin appears to lower cholesterol levels, as well as support joint collagen in examples of rheumatoid arthritis.
Epigallocatechin gallate (EGCG):
Polyphenols, most notably EGCG, or epigallocatechin gallate, are well-studied and powerful components of tea. EGCG has been shown to reduce colon and breast cancer risk. Green tea also boosts the immune system and encourages T-cell formation – part of the front-line defense of our bodies against sickness and disease.
Q. I’ve been seeing articles about fruits, vegetables and supplements touting “high ORAC value.” What does this mean?
ORAC is an acronym for Oxygen Radical Absorption Capacity, and is simply a measurement of antioxidant activity of nutrients. Oxygen radicals, or free radicals, are unstable molecules. They grab electrons from other cells to use for themselves, and in the process can damage them. It is believed that free radical activity plays a role in the development of many diseases such as heart disease and cancer, and also plays a role in aging.
Antioxidants help prevent this damage by “loaning out” extra electrons to stabilize free radicals/ Consider any fruit or vegetable with a high ORAC rating as having a lot of “antioxidant power.”
I know I should eat more fruits and vegetables, but it just seems so hard to get five servings a day.
The number one excuse I hear for not buying frits and veggies is that “fruits and vegetables are too expensive.” But are they really? Certainly, fresh foods that aren’t in season and have to be shipped a distance can be a bit pricey. If anyone added up how much spend on fast food, or prepackaged or processed snacks, it would probably be shocking.
Luckily, there are many ways to get your “Daily 5”. For instance, frozen fruits and veggies retain much of their nutrient profile. They can be an excellent alternative when certain foods are out of season. So too, are fruit and vegetable drink mixes – excellent supplemental sources of some of the nutrients our bodies need most.
More recently, the American
Of course, for people not accustomed to the fiber in fruits and veggies, there is some reason to think it’ll increase gas. When cell walls break down, and fiber passes through the system, it can create flatulence. Folks who eat fruits and vegetables every day generally don’t have this problem. Their systems are already accustomed to it.
For those just starting out on a better diet, however, start slowly – it helps your body adapt. Cooking vegetables can help, too, because it begins breaking down the cell walls early on.
One thing is certain, however. The “Typical American Diet” and good health are mutually exclusive. The increase in type 2 diabetes, heart disease, high cholesterol, and hypertension all point to the abuse our bodies suffer by eating diets high in fatty meats, processed sugars, and refined grains.
Q. Can I just drink fruit and vegetables drinks in place of 5 servings of fruits and vegetables?
Green drinks and fruit and vegetable drink mixes aren’t meant to replace whole foods, but they can be an excellent substitute when you’re rushed or traveling or just trying to fill everyday nutritional gaps. Their whole food ingredients absorb very easily and gently in the gut, and many of these drink mixes contain healthy doses of fiber, too.
Green drink mixes and food-based drink mixes combine many colorful fruits and vegetables and sometimes grasses in a healthy, mixable supplement assortment. While there have been many advancements in the field of green drinks, there are only a few that take the primary reason we eat into consideration: taste!
Happily, there are some companies out there with great-tasting drink mixes that also formulate based on the color concept, ensuring you get the broadest assortment of nutrients from a full range of fruit and vegetable colors to promote optimal health.
High-quality fruit and vegetable drink mixes offer the best from nature’s color wheel in a convenient and great-tasting supplement. So, the next tie you feel like taking a coffee break – try a fruit and veggie break instead. Your body and spirit will thank you.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1451) Benefits of Acetyl-L-Carnitine
Date:
February 12, 2006 01:55 PM
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1216) Lithium Aspartate improve brain function
Date:
January 03, 2006 05:32 PM
Lithium has long been known to be an effective therapy for Bipolar Disorder (manic depression) when taken in high doses. However, recent research has shown that low doses of lithium preserve and renew brain cells. Eight out of ten persons given lithium showed an increase in brain grey matter of 3 % after only 4 weeks. By promoting brain cell regeneration and increasing brain size lithium can function as an anti-aging nutrient for the brain. Lithium Aspartate may help increase brain function when taken daily. have you had your lithium today? :)
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1162) Phosphatidyl Serine - HEALTHY COGNITION BRAIN FUNCTION
Date:
December 21, 2005 11:04 AM
“To the dull mind, nature is leaden. To the illumined mind, the whole world burns and sparkles with light.” Ralph Waldo Emerson From the moment we rise to the moment we rest, our brain is in a decision-making frenzy. When we’re thirsty, our brain tells us that we need water. When we’re hungry, it reminds us that we have a refrigerator full of food. When we’re tired, it lets us know that we need to sleep, and so on. But despite the thousands of decisions we make everyday, our brain still hasn’t figured out a way to let us know what it needs to func¬tion. Though ironic, this raises a very serious issue. The human brain, like every other organ in the body, demands nutrition - period. Unfortunately, it leaves that up to us to figure out. Thanks to notable advance¬ments in research, we’re finally learning which nutri¬ents are most important for optimal brain function. Phosphatidyl Serine (PS) is a perfect example. This naturally occurring phospholipid has been the subject of numerous studies regarding its ability to boost cognitive function and delay (or potentially reverse) memory deterioration, and suggests that PS may be able to increase the effectiveness of neural transmissions. Interestingly, PS accounts for roughly 15% of the brain’s phospholipid supply. This is enor¬mous because phospholipids play a significant role in the billions of neurotransmissions that take place every second. Yes, billions. brain cells are constantly communicating with one another, and send astonishing amounts of impulses throughout the nervous system. This is accomplished via neurotransmitters - chemical messengers that send and receive impulses over the synapses of the brain and throughout the body. Mentally, we’re function¬ing at our best when these cells are well nourished. We can think more clearly, recall memories with ease and operate with greater efficiency. However, a de¬ficiency in neural-nutrients can prevent these mind messengers from functioning as they should. For¬tunately, PS has the ability to cross the blood-brain barrier to deliver critical nutrients and remove mind-slowing waste. Consider this. The brain functions in the same man¬ner that a major airport does around the holidays. There are millions of actions taking place. Impulses departing, nutrients arriving, endless communication, the occasional problem and more reactions than any¬one could possibly count. There’s confusion, delay and emotion, not to mention the endless series of transmissions that take place every second. Imagine PS as that ultra-motivated employee who shows up to work everyday anxious to expedite everything in sight. It helps neural travelers get to and from their respec¬tive gates, ensures that they have everything they need, simplifies processes that could result in breakdown, and clears isles that are cluttered with junk. Simply stated, PS is the brain’s overachieving go-getter. PS can help us think more clearly. It’s 3:06 in the afternoon and you’re scrambling to get to a meeting that you’re already late for. That fluster could be the result of poor neurotransmission caused by a deficiency in essential nutrients like PS. Moreover, these innocent brain-bursts can exhaust our PS reserves, leaving us somewhere hovering be¬tween frantic and sluggish. Every impulse, thought, action, reaction, movement, emotion and desire is the end result of neurotransmitters in action. PS is a major supporter of these actions. Therefore, as we increase the amount of PS in our system, we gain the ability to think and act with greater ease. PS can reduce the adverse impacts of stress on our body and mind. What do we do when we’re down in the dumps? While plopping down on the sofa with a snack might be an easy solution, it comes with a price. Not only does stress interfere with mood, but it can also inspire inactivity, over-eating and sluggishness. This is due largely in part to cortisol - a catabolic hormone released by the adrenal glands in response to emotional stress. Studies done to determine the effectiveness of PS on cortisol suppression have shown that it works by suppressing the hormones that produce cortisol. As a result, supplementing with PS may be able to help reduce the amount of stress related hormones that ultimately leave us singing the blues. PS can expedite post workout recovery time. Endurance athletes who carefully monitor their body’s response levels are increasingly turning to PS. Immediately following strenuous activity, the body responds by releasing adrenocorticotropin (ACTH) – a hormone that discourages testosterone and encourages cortisol. By limiting ACTH pro¬duction, PS reduces the amount of muscle tissue breakdown that occurs during exercise. A common misconception is that muscles grow during exercise - wrong. In fact, muscles are torn down during ex¬ercise and grow in-between workouts – hence the term recovery. During recovery, PS helps prevent the activity of growth-inhibiting hormones. This helps athletes recover faster so their gains are realized more quickly. In short, Phosphatidyl Serine appears to be a completely safe and beneficial dietary supple¬ment that can offer a wide range of physical and mental health benefits. NOW® Phosphatidyl Serine is derived from soy leci¬thin, and includes Choline and Inositol – two metabolites that work synergistically to help in¬crease circulation and cognitive response.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1057) St. John’s Wort and HIV suppression
Date:
December 15, 2005 10:55 AM
St. John’s Wort and HIV suppression A study published online in Oct. 27th issue of Gene Therapy found that protein extracted from St. John’s wort (Hypericum perforatum) suppresses HIV-1 expression and inhibits its replication. Kamel Khalili, Ph.D., and researchers at Temple University school of Medicine’s department of neuroscience and Center for Neurovirology made the discovery while studying the effect of St. John’s wort extracts on cell growth and the behavior of brain cells in vitro. However, the researchers caution that the protein studied (named p27SJ) may not be present in the St.John’s wort available in supplement form. “We don’t know yet how we have to deliver the protein to cells infected with HIV-1,” Khalili said. “Even if the protein were present in the tablets, we don’t know how much might be present and whether the protein would be effective when ingested.”
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=1015) Depressed? Try these “super 5” supplements
Date:
August 09, 2005 03:25 PM
Depressed? Try these “super 5” supplements While we must first address basic health issues and tackle them individually, nature has provided us with a number of compounds capable of treatment depression by safely raising serotonin levels and by boosting oxygen supplies to brain cells. 1. 5-HTP, a metabolite of the amino acid tryptophan, has the ability to boost serotonin production without the negative side effects of drugs like Prozac. It has been successfully used in clinical trials with people suffering from depression that were resistant to traditional therapies. Because it can boost serotonin without the negative side effects of antidepressant drugs, it is one of nature’s best choices as a natural remedy for depression, anxiety and sleep disorders. 2. St. John’s worth as received considerable attention for its ability to successfully treat mild to moderate depression. Numerous studies have concluded that many patients respond as well or better to St. John’s wort than standard drugs. Not surprisingly, German doctors prescribe St. John’s wort four times as often as Prozac for depression. 3. Ginkgo has enjoyed tremendous popularity as an herb capable of boosting memory function. Because depression is viewed by some experts as a condition of brain under-stimulation, ginkgo may be valuable in that it can boost brain cell oxygenation by enhancing blood flow. A French study found that 166 patients with mental disorders significantly improved with ginkgo therapy. 4. Phenylalanine and Tyr osine are two amino acids which elevate serotonin levels and curb excess carbohydrate cravings. Dr. Oscar Janifer, M.D. in his book A Different Kind of Healing, comments: “I’ve had great results with tyrosine. It’s like a natural antidepressant and is a precursor to the neurotransmitter norepinephrine.” Phenylalanine acts as precursor to the amines that comprise neurotransmitters (serotonin) in the brain. 5 . NADH, a form of niacin, plays a vital role in the energy production of all cells and is thought to boost brain cell metabolism. It is currently used for Alzheimer’s disease and seems well suited to older individuals suffering fro m depression. NADH levels significantly decline with age. Virtually any physical stressor can disrupt delicate chemical balances in the brain causing us to feel unexplainably sad for prolonged periods of time. Take a moment to evaluate your life, and look into natural means for assistance.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=729) THE FDA AND STEVIA
Date:
July 15, 2005 12:45 PM
THE FDA AND STEVIA While stevia in no way qualifies as an “artificial sweetener,” it has been subject to rigorous inquiry and unprecedented restraints. In 1986, FDA officials began to investigate herb companies selling stevia and suddenly banned its sale, calling it “an unapproved food additive.” Then in 1991, the FDA unexpectedly announced that all importation of stevia leaves and products must cease, with the exception of certain liquid extracts which are designed for skin care only. They also issued formal warnings to companies and claimed that the herb was illegal. The FDA was unusually aggressive in its goal to eliminate stevia from American markets, utilizing search and seizure tactics, embargoes and import bans. Speculation as to why the FDA intervened in stevia commerce points to the politics of influential sugar marketers and the artificial-sweetener industry. During the same year, the American Herbal Products Association (AHPA) began their defense of the herb with the goal of convincing the FDA that stevia is completely safe. They gathered documented literature and research on both stevia and other non-caloric sweeteners. The overwhelming consensus was that stevia is indeed safe, and the AHPA petitioned the FDA to exempt stevia from food additive regulations. Food Additive vs. Dietary Supplement FDA regulations of stevia were based on its designation as a food additive. The claim was that scientific study on stevia as a food additive was inadequate. Ironically, extensive Japanese testing of stevia was disregarde—regardless of the fact that this body of documented evidence more than sufficiently supported its safe use. Many experts who have studied stevia and its FDA requirements have commented that the FDA wants far more proof that stevia is safe than they would demand from chemical additives like aspartame. Stevia advocates point out that stevia not a food additive, but rather, a food. Apparently, foods that have traditionally been consumed do not require laborious and expensive testing for safety under FDA regulations. The fact that so many toxicology studies have been conducted in Japan, coupled with the herb’s long history of safe consumption, makes a strong case for stevia being accepted by the FDA as a safe dietary substance. Still, it was denied the official GRAS (generally recognized as safe) status and designated a food additive by the FDA. The FDA Reverses Its Position As a result of the Health Freedom Act passed in September of 1995, stevia leaves, stevia extract, and stevioside can be imported to the United States. However, ingredient labels of products that contain stevia must qualify as dietary supplements. Stevia had been redesignated as a dietary supplement by the FDA and consequently can be legally sold in the United States solely as a supplement. Its addition to teas or other packaged foods is still banned. Moreover, stevia cannot, under any circumstances, be marketed as a sweetener or flavor enhancer. SUGAR, SUGAR EVERYWHERE Ralph Nader once said, “If God meant us to eat sugar, he wouldn’t have invented dentists.” The average American eats over 125 pounds of white sugar every year. It has been estimated that sugar makes up 25 percent of our daily caloric intake, with soda pop supplying the majority of our sugar ingestion. Desserts and sugar-laden snacks continually tempt us, resulting in an escalated taste for sweets. The amount of sugar we consume has a profound effect on both our physical and mental well-being. Sugar is a powerful substance which can have drug-like effects and is considered addictive by some nutritional experts. William Duffy, the author of Sugar Blues, states,“The difference between sugar addiction and narcotic addition is largely one of degree.” In excess, sugar can be toxic. Sufficient amounts of B-vitamins are actually required to metabolize and detoxify sugar in our bodies. When the body experiences a sugar overload, the assimilation of nutrients from other foods can be inhibited. In other words, our bodies were not designed to cope with the enormous quantity of sugar we routinely ingest. Eating too much sugar can generate a type of nutrient malnutrition, not to mention its contribution to obesity, diabetes, hyperactivity, and other disorders. Sugar can also predispose the body to yeast infections, aggravate some types of arthritis and asthma, cause tooth decay, and may even elevate our blood lipid levels. Eating excess sugar can also contribute to amino acid depletion, which has been linked with depression and other mood disorders. To make matters worse, eating too much sugar can actually compromise our immune systems by lowering white blood cells counts. This makes us more susceptible to colds and other infections. Sugar consumption has also been linked to PMS, osteoporosis and coronary heart disease. Why Do We Crave Sweets? Considering the sobering effects of a high sugar diet, why do we eat so much of it? One reason is that sugar gives us a quick infusion of energy. It can also help to raise the level of certain brain neurotransmitters which may temporarily elevate our mood. Sugar cravings stem from a complex mix of physiological and psychological components. Even the most brilliant scientists fail to totally comprehend this intriguing chemical dependence which, for the most part, hurts our overall health. What we do know is that when sugary foods are consumed, the pancreas must secrete insulin, a hormone which serves to bring blood glucose levels down. This allows sugar to enter our cells where it is either burned off or stored. The constant ups and downs of blood sugar levels can become exaggerated in some individuals and cause all kinds of health problems. Have you ever been around someone who is prone to sudden mood swings characterized by violent verbal attacks or irritability? This type of volatile behavior is typical of people who crave sugar, eat it and then experience sugar highs and lows. Erratic mood swings can be linked to dramatic drops in blood sugar levels. Hypoglycemia: Sign of Hard Times? It is rather disturbing to learn that statisticians estimate that almost 20 million Americans suffer from some type of faulty glucose tolerance. Hypoglycemia and diabetes are the two major forms of blood sugar disorders and can deservedly be called modern day plagues. Hypoglycemia is an actual disorder that can cause of number of seemingly unrelated symptoms. More and more studies are pointing to physiological as well as psychological disorders linked to disturbed glucose utilization in brain cells. One study, in particular, showed that depressed people have overall lower glucose metabolism (Slagle, 22). Hypoglycemia occurs when too much insulin is secreted in order to compensate for high blood sugar levels resulting from eating sugary or high carbohydrate foods. To deal with the excess insulin, glucagon, cortisol and adrenalin pour into the system to help raise the blood sugar back to acceptable levels. This can inadvertently result in the secretion of more insulin and the vicious cycle repeats itself. A hypoglycemic reaction can cause mood swings, fatigue, drowsiness, tremors, headaches, dizziness, panic attacks, indigestion, cold sweats, and fainting. When blood sugar drops too low, an overwhelming craving for carbohydrates results. To satisfy the craving and compensate for feelings of weakness and abnormal hunger, sugary foods are once again consumed in excess. Unfortunately, great numbers of people suffer from hypoglycemic symptoms. Ironically, a simple switch from a high sugar diet to one that emphasizes protein can help. In addition, because sugar cravings are so hard to control, a product like stevia can be of enormous value in preventing roller coaster blood sugar levels. One Colorado internist states: People who are chronically stressed and are on a roller coaster of blood sugar going up and down are especially prone to dips in energy at certain times of day. Their adrenals are not functioning optimally, and when they hit a real low point, they want sugar. It usually happens in mid-afternoon when the adrenal glands are at their lowest level of functioning. (Janiger, 71) Our craving for sweets in not intrinsically a bad thing; however, what we reach for to satisfy that craving can dramatically determine how we feel. Stevia can help to satisfy the urge to eat something sweet without changing blood sugar levels in a perfectly natural way and without any of the risks associated with other non-nutritive sweeteners. Diabetes: Pancreas Overload? Diabetes is a disease typical of western cultures and is evidence of the influence that diet has on the human body. Perhaps more than any other disease, diabetes shuts down the mechanisms which permit proper carbohydrate/sugar metabolism. When the pancreas no longer secretes adequate amounts of insulin to metabolize sugar, that sugar continues to circulate in the bloodstream causing all kinds of health problems. The type of diabetes that comes in later years is almost always related to obesity and involves the inability of sugar to enter cells, even when insulin is present. Diabetes can cause blindness, atherosclerosis, kidney disease, the loss of nerve function, recurring infections, and the inability to heal. Heredity plays a profound role in the incidence of diabetes, but a diet high in white sugar and empty carbohydrates unquestionably contributes to the onset of the disease. It is estimated that over five million Americans are currently undergoing medical treatment for diabetes and studies suggest that there are at least four million Americans with undetected forms of adult onset diabetes. Diabetes is the third cause of death in this country and reflects the devastating results of a diet low in fiber and high in simple carbohydrates. Most of us start our children on diets filled with candy, pop, chips, cookies, doughnuts, sugary juice, etc. Studies have found that diabetes is a disease which usually plagues societies that eat highly refined foods. Because we live in a culture that worships sweets, the availability of a safe sweetener like stevia, which does not cause stress on the pancreas is extremely valuable. If sugar consumption was cut in half by using stevia to
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=642) THE FDA AND NON-CALORIC SWEETENERS
Date:
July 15, 2005 12:27 PM
THE FDA AND NON-CALORIC SWEETENERS While white sugar, turbinado, fructose, honey and corn syrup all qualify as natural sweeteners, none of these are calorie- free nor can they be used by people who suffer from blood sugar disorders. They can encourage weight gain, tooth decay, raise blood sugar quickly, and can also predispose certain individuals to yeast infections. These sugars can also contribute to indigestion, bowel disorders and, possibly, hyperactivity or ADD in children. Pharmaceutical sweeteners like aspartame and saccharin qualify as calorie-free but come with significant limitations and health risks. Saccharin has been labeled with a warning that it has caused the development of cancer in laboratory animals but is still available for purchase. In 1970, cyclamates, another class of artificial sweeteners, were banned because of the strong possibility that they are, in fact, carcinogenic. Aspartame has been marketed as a safe substance for the general public, except for those few individuals who suffer from PKU (phenylketonuria), a relatively rare disorder. Most consumers assume that aspartame is a perfectly benign compound and use it liberally. It is, in fact, comprised of phenylalanine, aspartic acid, and methanol (wood alcohol). As previously mentioned, various side effects have been associated with the ingestion of aspartame and include migraines, memory loss, slurred speech, dizziness, stomach pain, and even seizures. In addition, because aspartame contains chemicals which affect brain cell function, significant questions have been raised concerning its link to increased incidence of brain tumors (Olney). Acesulfame K, another artificial sweetener on the market, has also been linked to cancer by the Center for Science in the Public Interest. Despite the protest of various organizations and health professionals, these pharmaceutical s weeteners have been approved by the FDA and are recognized as safe.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=641) Life Force - The Energy Activator
Date:
June 29, 2005 10:35 AM
Don’t Be Confused About Multiples – Get the Top-Ranked Multiple That Scores 100% We can help you decide how to pick the most advanced daily multiple for your wellness. Listen to the experts. Source Naturals LIFE FORCE MULTIPLE was honored as a leading formula in an independent scientific analysis of 500 multiples, ranking higher than any other national brand. Lyle MacWilliam, author of the Comparative Guide to Nutritional Supplements (ide.com) ranked multiples based on criteria developed from the published recommendations of the most renowned nutritional authorities: Phyllis Balch, C.N.C.; Michael Colgan, Ph.D.; Earl Mindell, Ph.D.; Michael Murray, N.D.; Richard Passwater, Ph.D.; Ray Strand, M.D.; and Julian Whitaker, M.D. Source Naturals’ success in this rigorous scientific analysis reflects our Bio-Aligned™ formulation method. LIFE FORCE goes deep to the underlying cause of health imbalances by supporting multiple body systems. And now, based on the latest scientific research, we have improved the formula by adding even more antioxidants and other cutting-edge ingredients. According to Lyle MacWilliam, “Source Naturals made a top ranked multiple even better!” And based on Lyle’s analysis of the new formula, LIFE FORCE is now the highest rated multiple of any evaluated in the current edition of this guide, scoring a 100% rating. Bio-Align™ Yourself with Life Force LIFE FORCE MULTIPLE was chosen as one of America’s most elite and comprehensive multiples, as reported in the Comparative Guide to Dietary Supplements by Lyle MacWilliam, 3rd ed. LIFE FORCE received this acknowledgement by nutrition experts because it is uniquely effective. This Bio-Aligned Formula™ goes beyond ordinary multiples that simply replace nutrients missing from the diet. LIFE FORCE provides key organ-specific nutrients to support your body’s energy generation, heart, brain, immune system, musculoskeletal system, skin, liver, eyes, and more. When all your body systems function in harmony, everything in life comes together. Your mood is positive, your mind is clear, you’ve got energy in your step—that’s your LIFE FORCE working for you. Get Ahead with Activated Energy and a Healthy Metabolism Your metabolism determines how much you weigh, how energetic you feel, and the effective functioning of all your systems. LIFE FORCE is a rarity – a unique multiple containing an incredible number of nutrients at the potency levels that truly support your healthy metabolic function. For example, it contains coenzyme Q10, which plays a crucial role in cellular energy production. CoQ10 is a vital intermediate in the electron transport chain, one of the body’s energy production cycles, which converts glucose, or blood sugar, into ATP (Adenosine Triphosphate), a high energy molecule that is the body’s “energy currency.” LIFE FORCE also supplies alpha-lipoic acid and the potent R-lipoic acid form of lipoic acid, which are both referred to as the universal antioxidants and important intermediaries in the Krebs cycle, another energy production cycle. LIFE FORCE also contains tyrosine and iodine, both precursors to thyroid hormones. These hormones regulate key metabolic functions like heart rate, digestive function, weight management and energy levels. No discussion of metabolism would be complete without mentioning the B vitamins and their coenzymated forms, such as thiamin cocarboxylase, riboflavin mononucleotide, and the methylcobalamin form of vitamin B- 12. These critical vitamins and their immediately bioavailable coenzymated forms are formulated to play critical roles in thousands of enzyme reactions that promote carbohydrate metabolism, energy production, and the mental functions that invigorate and activate you as you move through your busy days. And now green tea extract with EGCG (Epigallocatechin Gallate) has been added to the formula for added metabolic support. Protect Your Heart and Circulatory System The amazing muscular organ that is your heart beats more than 100,000 times a day, 365 days a year, promoting vitality and alertness by constantly oxygenating our tissues. LIFE FORCE supports your cardiovascular system with antioxidant coenzyme Q10, which helps support heart muscle metabolism. LIFE FORCE also contains the minerals potassium and magnesium, electrolytes vital for healthy heartbeat and heart function, and the herb hawthorn, a rich source of antioxidant flavonoids, which has traditionally been used as a heart tonic. LIFE FORCE also supplies vitamins B-6, B-12 and folic acid to help maintain healthy homocysteine levels and vitamin K to support healthy circulation. Unlike common multiples, it supports cholesterol wellness, circulatory health and antioxidant cardiovascular protection, with both the typical d-alpha form of vitamin E but and the more potent and effective gamma-tocopherol and similarly structured tocotrienols. Skin and Musculoskeletal Support LIFE FORCE furnishes nutrients to build healthy bones, muscles and skin. We all know that calcium and magnesium are crucial for bone health, but many people don't know that there are a variety of nutritional cofactors that help build bone, such as vitamin D (which enhances calcium absorption and utilization), boron, manganese and copper. LIFE FORCE also supplies vitamin C and copper, necessary nutrients for collagen production (collagen is a key constituent of connective tissue in joints, skin and other areas), and the cutting-edge nutrient methylsulfonylmethane (MSM), an assimilable form of the mineral sulfur, used by the body to build and maintain connective tissues, including joint cartilage, hair, skin and nails. Additional nutraceuticals to support healthy skin include DMAE bitartrate, CoQ10, and alpha lipoic acid. LIFE FORCE also now includes rutin, quercetin, green tea extract and 65% more turmeric extract for your joint comfort. Brain and Nerves Nutrition The hectic pace and constant demands of life can keep our pulse racing, our nerves jangling and our temples throbbing. Our nervous systems are crying out, “Help!” LIFE FORCE provides that help. LIFE FORCE supplies the most highly bioavailable and bioactive forms of the amino acid tyrosine – the N-acetyl form and the acetyl-L form. Tyrosine is an important precursor to epinephrine and norepinephrine (collectively known as the catecholamines), which helps you respond to stress. It also contains high doses of vitamins C and B-6, required by the adrenal glands to produce the catecholamines. In addition, LIFE FORCE delivers the full spectrum of B vitamins, all important for healthy nervous system function. Now LIFE FORCE also contains a more bio-available form of tyrosine, acetyl-L-Tyrosine. And LIFE FORCE contains Neuroceutical® nutrients that support healthy brain function by furnishing DMAE and choline. Both are precursors to the important neurotransmitter acetylcholine and are important for memory focus and muscular movement. Choline is also a precursor to phosphatidylcholine, an important constituent of the cellular membranes that surround and protect our brain cells. In addition, LIFE FORCE contains the renowned herb Ginkgo biloba and now even more grape seed extract, both effective antioxidants that can prevent lipid peroxidation, which is critically important for the high amounts of fatty tissue in the brain. LIFE FORCE—good food for the brain. Immune Defense LIFE FORCE MULTIPLE supports your immune system, so you can feel your best through the seasons. LIFE FORCE contains the immunosupportive nutrient vitamin A, which fosters cell-mediated immunity and protects the epithelial linings of the respiratory and digestive tracts. Two forms of vitamin A are supplied: preformed vitamin A and its precursor, the potent antioxidant betacarotene. Other immuno-supportive nutrients in LIFE FORCE include vitamin B-6, vitamin C and zinc, which is fundamental for proper functioning of our T-cells, the “seek and destroy” cells of our immune system. LIFE FORCE also now includes 40% more lipoic acid, including the highly bioavailable alpha and R-isomer forms. Lipoic acid along with the B vitamins and CoQ10 promote building the energy reserves needed when the immune system needs to kick into high gear. Powerful Liver Support Your liver is responsible for converting many nutrients into their metabolically active forms before your body can use them. After activation, these nutrients travel through the blood stream to target organs where they perform their metabolic functions. Not only does the liver activate nutrients, but it also plays a crucial role in a variety of other metabolic functions, from fat digestion and cholesterol production to blood sugar regulation to the processing and elimination of toxins, an important role in today’s increasingly polluted world. For all these reasons, nourishing the liver is crucial. And LIFE FORCE does just that. LIFE FORCE contains alpha-lipoic acid, turmeric, silymarin and N-acetyl cysteine (NAC) – all potent antioxidants that support healthy liver function. NAC and alpha-lipoic acid both help produce glutathione, one of the liver’s primary detoxifying molecules. Silymarin, the active flavonoid complex of the herb milk thistle, as well as coenzyme Q10, have been shown in vitro to inhibit lipid peroxidation of cell membranes. Turmeric extract promotes bile flow and is a rich source of the antioxidant, curcumin. LIFE FORCE also contains choline and inositol, vitamin- like molecules which act as lipotropics, unique substances that prevent the deposition of fat in the liver. Since the liver is naturally high in fats, LIFE FORCE is one of the only multiples that contains the fat-soluble form of vitamin C, ascorbyl palmitate, for antioxidant protection. Complete Antioxidant Defense Oxidative stress is the primary cause of accelerated aging. This and other forms of free radical damage are constantly threatening your body. Whether it is from pollution, ultraviolet light, food additives, or from other sources, it is more critical than ever to protect your body with antioxidants. LIFE FORCE contains 24 of the most powerful antioxidants known to science, including eight new antioxidants based on the latest research. It contains antioxidants that are water soluble, such as quercetin and rutin, and ones that are fat soluble, such as alpha-lipoic acid and lycopene. There are antioxidants that are especially protective of specific body systems, such as lutein to protect the macula in your eye, lycopene to protect your prostate gland, and tocotrienols to protect your arteries. Cutting-Edge Vision Nutrition The structure and functions of your eyes are very complex. LIFE FORCE contains nutrients to help support and maintain healthy eye tissue, which is particularly susceptible to oxidative stress from free radicals. To support your healthy macula, aqueous tissue and optical nerve signals, LIFE FORCE includes ingredients such as lutein, astaxanthin, beta carotene, bilberry, zinc, lipoic acid and quercetin. Life Force Replenishes Essential Nutrients to Support Your Low Carb Lifestyle LIFE FORCE contains optimal levels of many nutrients that might be deficient in low carb meals. Counting carbs can lead to restrictions of nutrient-dense foods, such as dairy products, grains, fruits and vegetables. LIFE FORCE contains many of the same protective antioxidants, vitamins and minerals as fruits and vegetables, including betacarotene, vitamin C, vitamin E, flavinols, magnesium and selenium. It also contains high levels of the same vitamins found in grains, including all of the B vitamins, to support your body’s healthy energy metabolism. And it contains nutrients found in dairy products, such as calcium, potassium, vitamin A and vitamin D. Support Healthy Fat and Protein Consumption with Life Force Low carb lifestyles mean higher consumption of proteins and fats. Unfortunately, there are artery, heart, colon and many other health concerns associated with meals that are high in fat and protein and low in fiber and produce. However, the nutrients in LIFE FORCE can help you better process these foods when eating this way. LIFE FORCE contains high levels of protective fat-soluble antioxidants such as alpha lipoic acid, ascorbyl palmitate (vitamin C ester) and vitamin E to protect your body from the free radicals generated by consuming more fats. It also contains many nutrients for liver health, such as silymarin, CoQ10, NAcetyl Cysteine and turmeric to help support the fat metabolism your liver is responsible for. LIFE FORCE also contains a high level of the B vitamin biotin, which aids in fat, protein and energy metabolism. Complete Energizing Nutrition LIFE FORCE is the only multiple to target organ systems with specific nutrients and bio-botanicals, antioxidants and Neuroceuticals® for total body harmony and energy activation, system by system. Only this dedication to going deep to the cellular root of system imbalances can produce a multiple so effective that it is acknowledged in a prestigious scientific review, the Comparative Guide to Nutritional Supplements. A nutritional program with LIFE FORCE at its center can be an easy first step in joining the Wellness Revolution. The goal of this revolution is a long, healthy and fulfilling life. Allow yourself to feel your best, to achieve mental and physical harmony, to radiate energy and vitality. Feel your LIFE FORCE!
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=520) ALPHA GPC - Improves Mental Performance
Date:
June 28, 2005 06:21 PM
The quality of our life experience—and our ability to live life to the fullest—is a direct result of optimal brain function. Only a few years ago, nothing could be done to stem the tide of poor circulation, forgetfulness and “mental fog.” But neurological science exploration has identified a fundamental brain compound critical to attention, learning, memory, and even the higher cognitive functions of reasoning and intuition. Research confirms that L-alpha-glycerylphosphorylcholine (called Alpha-GPC for convenience) is crucial to neuronal function and structure. Derived from purified soy lecithin, Source Naturals ALPHA-GPC readily converts to acetylcholine in the brain, helping to maintain neuronal structure integrity. Source Naturals provides an easy and convenient means to profoundly impact the very nexus of our body and mind. GPC Is Unique No other nutritional compound comes close to GPC in its ability to boost critically important acetylcholine levels. Found in both the brain and the peripheral nervous system (including the nerve-muscle junctions), acetylcholine is a key nerve messenger molecule, or neurotransmitter. Aging brains are characterized by functional deficiencies in both acetylcholine and its cholinergic receptors. GPC is a highly bioavailable supplement that boosts acetylcholine levels to improve cognitive function. It is also a major choline reservoir, helping to protect the brain against damage from poor circulation and potentially toxic metabolites. Deficiencies in acetylcholine can cause the body to break down phosphatidylcholine for its choline content, leading to the death of brain cells. Yet in controlled clinical trials of middle-aged subjects taking GPC, reaction time was enhanced and there was improved energy generation and electrical coordination in the brain. For older subjects, double-blind trials demonstrated that GPC had superior benefits over certain other brain nutrients for mental focus, recall, verbal fluency—a unique, marked overall enhancement of mental performance. GPC is an example of what the great Linus Pauling referred to as “orthomolecules,” that is, molecules that are “orthodox” or “correct” for the body. GPC excels as a protective nutraceutical for memory loss and mood enhancement. It protects cells of the brain (and other organs) from damage, shielding a range of important biomolecules against toxin build-up. Extensive Clinical Testing In clinical trials that involved more than 5,000 patients, GPC showed marked improvement in overall brain performance. Depending on the particular trial, 50-70 percent of the patients who received GPC had their mental functions improved to a degree “meaningful to life quality.” GPC has shown revitalizing effects on the declining brain, and preliminary evidence suggests GPC may act on the pituitary gland to partially restore its capacity to make vital for cell maintenance and longevity. Other unique brain features of GPC are its benefits for attention and recall in young healthy adults, and its superior bioavailability. GPC readily crosses the bloodbrain barrier to raise brain choline levels within a few hours following oral intake. GPC helps with body-mind integration by being a ready reservoir for acetylcholine. This neurotransmitter is ubiquitous in brain circuit maturation, expansion, renewal and repair, as well as in the “agility” or adjustments of the circuitry that occur during adult life. In addition, an animal study has shown that GPC increases the release of GABA (gamma-aminobutyric acid), the most important and abundant inhibitory neurotransmitter in the brain. It acts as a “balancer” for the brain and helps induce relaxation and sleep. Without sufficient GABA, neurons fire at random, unable to make sense of incoming signals. GABA helps minimize “neural noise,” making it easier to focus and concentrate. Why you should take GPC:
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(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=514) Promilin Fenugreek Extract - Supports Healthy Blood Sugar Levels
Date:
June 28, 2005 10:44 AM
.. Your body’s ability to manage blood sugar may well be the single most crucial factor affecting your health and longevity, and the one most affected by diet and lifestyle. But today’s high-glycemic carbs and sugar-laden foods — combined with lack of exercise — are creating a serious challenge to your body’s intricate glucose/insulin regulatory system. The resulting cellular stress and deterioration have serious repercussions for both your mind and body. To promote optimal wellness through healthy sugar metabolism, Source Naturals formulated PROMILIN™ FENUGREEK EXTRACT, a potent extract from the highly valued herb fenugreek, into an advanced nutritional supplement designed to assist insulin production and support healthy glucose levels. As a complement to your diet, Source Naturals PROMILIN™ FENUGREEK EXTRACT is an excellent strategy to improve blood sugar levels, and consequently, quality of life. The basis of Source Naturals PROMILIN™ FENUGREEK EXTRACT is fenugreek (Trigonella foenum-graecum), a respected culinary and medicinal herb used throughout history. One of the formula’s fenugreek extracts is rich in galactomannan, a mucilaginous fiber that may benefit the bowel. The other extract is Promilin, a patent-pending complex of bioactive amino acids standardized to contain 20% 4-hydroxyisoleucine. This extraordinary amino acid derivative assists the pancreas in production of insulin. Several studies with animals and with human cell cultures demonstrate this extract’s positive effect on reducing post-meal glucose levels — with little or no increase in blood insulin concentrations — a clear indicator of improved insulin sensitivity. Sports Nutrition and Blood Sugar Athletic energy and endurance depend on the ability of muscles to recover from exercise. Because PROMILIN promotes utilization of glucose and insulin by the the body’s muscle cells, “weekend warriors” will feel less fatigue on Monday morning. In a clinical study, PROMILIN increased glycogen re-synthesis by 63% over carbohydrate alone. This is the rate at which post-exercise muscle glycogen (energy) is restored. PROMILIN may also play a role in weight management because it helps your body metabolize carbohydrates more efficiently. And the less time glucose spends in your bloodstream, the less chance it will be converted into fat. By supporting glucose metabolism, Source Naturals PROMILIN™ FENUGREEK EXTRACT may help protect against a harmful process called glycation, where excess glucose reacts with amino acids to form crosslinked sugardamaged proteins that damage the linings of blood vessels, the lens of the eye, and the myelin sheath that insulates brain cells.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=513) TRADITIONAL USES
Date:
June 25, 2005 01:08 PM
TRADITIONAL USES Folk tales and myths surround the ginseng plant in all its varieties. It was thought to be the ultimate herb for strength, vigor and a long life. The Asian ginseng used throughout China was thought of as the ultimate cure-all. It has been highly esteemed and used for thousands of years. Ginseng is stimulating on the entire body to help overcome stress, increase longevity, fatigue, weakness, mental fatigue, improve brain cell function, and benefit the heart and circulation. It is also used to normalize blood pressure, reduce cholesterol levels, and to prevent artherioslcerosis. It is used to help protect the body against radiation and as an antidote to drugs and toxic chemicals. Ginseng is often given alone or in combination with other herbs to restore balance in the body. Folk medicine recommends ginseng for many ailments such as amnesia, cancer, atherosclerosis, asthma, diabetes, coughs, heart, fear, fever, epilepsy, hypertension, malaria, impotence, insomnia, longevity, swelling, sores and vertigo. It is probably safe to say that ginseng is one of the most popular and most prescribed natural remedies for just about anything. Ginseng has been used to rejuvenate the body and maintain health. It is used to promote regeneration at times of stress on the body. It also helps when the body has undergone illness or surgery. It is also thought to help increase longevity and keep the body looking young with less signs of aging. It is not only promoted for physical longevity but also for mental function. Ginseng is often used to help strengthen the male reproductive systems. It is thought to be especially healing on the prostate gland. It is also used as an aphrodisiac. Ginseng is also thought to produce some testosterone in women, and for this reason, is not recommended for long periods of time. Panax ginseng is thought to increase male hormone production.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=482) Summary of Specific Actions Associated with Ginkgo
Date:
June 25, 2005 12:39 PM
Summary of Specific Actions Associated with Ginkgo
Unquestionably, ginkgo will continue to enjoy its current popularity. As baby boomers continue to enlarge the senior citize n block of our population, supplements which have the ability to deter or even prevent age-related disorders will be vigorously sought after.
Ginkgo can be used in these combinations for bioenhancement: Ginkgo: Primary Applications The following are general areas that ginkgo biloba can be used effectively:
Secondary Applications The following are areas of secondary application for ginkgo biloba:
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=465) The Cardiovascular System and Free Radicals
Date:
June 25, 2005 11:49 AM
The Cardiovascular System and Free Radicals It is the bioflavonoid content of ginkgo which enables the compound to scavenge free radicals so effectively. The flavonoids in ginkgo help protect cells against free radical contact. These flavonoids have an enzyme-regulating effect also found in citru-derived bioflavonoids with one important difference: the efficacy doses reported for ginkgo are much lower. In addition, these bioflavonoids provide protection to blood vessels against the damaging effect of plaque build-up. Scientists have discovered that is the antioxidant action of ginkgo which helps pre vent damage to heart muscle. Ginkgo reduces the formation of free radicals. Ginkgo may provide some protection from exposure to damaging ultraviolet light. The Brain’s Vulnerability to Oxidants The antioxidant action of ginkgo helps to keep ample supplies of oxygen to brain neurons which are involved in memory retrieval. The flavonoids in ginkgo help to decrease the metabolism of oxidants in brain cells which can help prevent reduced blood flow to brain tissue. The antioxidant properties of ginkgo are most evident in brain tissue, which is made up of nerve cells. brain cell membranes are compressed of a high percentage of unsaturated fatty acids which make them p a rticularly vulnerable to free radical damage and hypoxia (lack of oxygen). The brain has little in the way of energy reserves and requires a continual supply of glucose and oxygen. When circulation is compromised, both of these components are reduced. If blood flow is diminished enough, brain cells will die. Ginkgo helps these cells to utilize glucose and boosts oxygen supply. As a result, energy production in brain tissue is enhanced.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=455) Treating and Preventing Age-Related Mental Disorders
Date:
June 25, 2005 11:24 AM
Treating and Preventing Age-Related Mental Disorders Ginkgo biloba may be of great value in cases of age-related mental dysfunction including senility, Alzheimer’s disease and diminished memory. In Paris, P. R. Michil conducted a double-blind study in which 50 patients with moderate senile dementia were given either ginkgo or a placebo. Patients treated with ginkgo extract showed a significant improvement in their mood, sociability, and vigilance. Senility in the elderly is frequently the result of insufficient blood and oxygen flow to brain cells. Anytime this type of insufficiency occurs, short-term memory loss, ve rtigo, headache, malaise or depression can result. An extract derived from ginkgo leaves offers significant hope to anyone who suffers from diminished blood flow to the brain. In another large open trial involving 112 geriatric patients who suffered from inadequate cerebral blood flow, 120 mg. of ginkgo biloba extract was administered. The results showed a significant regression of pre-existing symptoms.5 What this study implies is that so-called “age - related disorders,” including senile dementia, may be caused by reduced blood flow to the brain rather than the actual degeneration of nerve cells. Ginkgo appears to increase oxygen utilization in brain tissue, which also enables neural cells to metabolized sugar more effectively.6
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=450) Increased Brain Power and Memory with Ginkgo
Date:
June 25, 2005 11:23 AM
Increased Brain Power and Memory with Ginkgo Ginkgo’s ability to enhance cognitive function is becoming common knowledge. Boosting the capability of the brain to record information, communicate ideas or recall concepts can all be enhanced by taking ginkgo biloba therapeutically. Evidently, providing a better oxygen supply to brain cells is ginkgo’s primary neural action. The brain is the body’s most sensitive organ to oxygen deprivation. Today, more than ever, the effects of smoking, alcohol and stress in general can diminish brain function and compromise mental alertness. Ginkgo has demonstrated over and over that it can make a significant difference in memory retrieval, fact retention and problem solving. One of the most impressive aspects of ginkgo is its ability to stimulate circulation and oxygen flow to neural tissue, there by improving cognitive functions and memory. In test cases when ginkgo has been administered, an increase in cerebro-circulation has been noted in both healthy or diseased brain tissue. What makes this finding particularly relevant is that other circulatory enhancers, whether natural or synthetic do not usually possess this capability. In addition, ginkgo increases oxygen transport at the blood-brain barrier site, while inhibiting the permeability of toxins into brain tissue. As well as boosting blood supply to the brain, ginkgo has demonstrated the ability to increase the rate at which information is transmitted at the nerve cell level.2 In a double-blind study, one group of healthy young women received ginkgo extract, and the other was given a placebo. A memory test was administered and the reaction time in those women who had taken the ginkgo improved significantly. These findings corresponded with EEG tracings which showed increased brain wave activity.3 Short-term memory and basic learning rates can be statistically improved by using ginkgo. Ginkgo’s ability to enhance memory may also be helpful for epileptics who take anticonvulsants. Typically, an anticonvulsant can impair memory function, making it difficult to retrieve names or numbers from memory banks. In addition, although research is lacking, because ginkgo stimulates brain function, it may help to inhibit improper discharging of electrical impulses which is the primary cause of seizures in epileptics. Ginkgo is rapidly gaining an impressive reputation as a brain enhancer. It has demonstrated its capability to improve memory, mental efficiency and the ability to concentrate. It has also been shown to reduce anxiety, headaches, tension, vertigo, and age-related cerebral disorders. Anyone who has suffered a stroke should look into the possible benefits of ginkgo to amplify mental function and clarity. Considerable research on ginkgo conducted in Eu rope has confirmed that ginkgo does indeed facilitate better arterial circulation as well as improve electrical transmission in the nerves. The latter function also contributes to improved oxygenation and nutrition to the brain.4 Ginkgo is now accepted as a brain booster which improves memory, mental efficiency, cognitive function, communication, orientation and the ability to concentrate. Recently, the notion of using ginkgo for learning disorders has received some attention. Forthcoming research on the subject will help to clarify its potential for treating such conditions.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=449) Fats: The Good, the Bad, the Ugly
Date:
June 14, 2005 11:18 AM
Fats: The Good, the Bad, the Ugly by Thomas Sherman Energy Times, October 15, 2004 We need fat to absorb vitamins, to keep our brains sharp, to survive. But not all fats are our friends. Find out which ones are the heroes and the villains in your diet. In a lot of cases health fads don't live up to their hype. But the case for consuming more good fats-the omega-3 fatty acids found primarily in fish, flax and hemp oils-is strong and growing stronger. As a nation we eat too little of these good fats, and our health would improve greatly if we relied a little less on the bad saturated fat in burgers, skipped the ugly trans fats in fries and indulged in more salmon and other seafoods. Fish and the Heart Need proof? A wealth of research supports fish oil's desirable effects, especially on heart health. While many people believe that heart disease is primarily a problem for men, women who have passed through menopause are just as susceptible to heart problems. " [Our] findings suggest that all women, and most likely men, would benefit from regular fish intake," says Alice H. Lichtenstein, DSc, director of the Cardiovascular Nutrition Laboratory at Tufts University in Boston. "A tuna fish sandwich counts, as does almost any other type of fish that is baked, broiled, grilled, or poached." But she points out that fried fish, which is often cooked in hydrogenated oils, is not helpful. In research on more than 200 women, performed at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts, scientists found that the arterial blockages among women who dined on fish were less (and impeded blood flow less) than in women who hardly ever ate seafood. Fish was especially helpful for women who had diabetes, a disease that makes you more prone to heart and circulation problems (American Journal of Clinical Nutrition 9/04). These effects are important: Heart disease is the number one cause of death for women, and older women who suffer from diabetes are particularly susceptible. The number of people with diabetes has been increasing of late, mainly due to the fact that Americans are overweight. Right now about 18 million people have diabetes and another 20 million are expected to suffer this condition in the next four decades. " This study shows that following the current guidelines of eating at least two servings of any type of fish per week slows down the progression of heart disease in women with coronary artery disease (CAD), especially those who were also diabetic," says Dr. Lichtenstein, coauthor of the study. "We further found that eating one or more servings per week of fish that is rich in omega-3 fatty acids, such as tuna or other dark-fleshed fish, is equally effective." Dangerous disruptions in heartbeat, known as arrhythmias, may also be affected by fish oil. "[E]xperiments show that fatty acids from omega-3 fish oils are stored in the cell membranes of heart cells and can prevent sudden cardiac death or fatal arrhythmias," notes Alexander Leaf, MD, medical researcher and professor at Harvard University. Fat for Your Brain The right kind of fat is also crucial for the function of your nerves and brain tissue, which is 60% to 70% fat. Incorporating omega-3 fatty acids into those cells can help keep your brain firing on all synapses. It may lower your risk of Alzheimer's disease, an irreversible form of mental deterioration that kills 100,000 Americans a year. About a thousand people a day in the US are found to have Alzheimer's, and experts believe that over the next 40 years 14 million of us will be doomed to being enveloped by the mental fog this condition produces. Research indicates that our brains probably need omega-3 fats for protection against the kind of damage that causes our mental capacities to slip. Once Alzheimer's starts, deterioration accelerates because brain cells start losing these fats. In experiments performed at the David Geffen School of Medicine at UCLA (Neuron 9/2/04), scientists looked at how a lack of docosahexaenoic acid (DHA, one of the omega-3 fats found in fish), affected the cellular processes that lead to Alzheimer's. They found that the part of brain cells that receive signals from other brain cells, the receptors, are vulnerable to damage from chemical reactions that take place inside the cells. However, DHA offers antioxidant protection against this destruction. When brain cells were denied DHA, the cells' receptors suffered extra harm. But when fish oil was present, brain cells were protected. In addition, animals that received extra omega-3s were better able to learn and find their way through mazes. Greg Cole, PhD, senior researcher on this study and a professor of neurology at Geffen, says, "We saw that a diet rich in DHA, or docosahexaenoic acid, dramatically reduces the impact of the Alzheimer's gene [which made the animals more susceptible to Alzheimer's]. Consuming more DHA is something the average person can easily control. Anyone can buy DHA in its purified form, fish-oil capsules, high-fat fish or DHA-supplemented eggs." Fishes rich in omega-3s include salmon, halibut, mackerel, sardines and herring. Protecting Kids from Asthma A surprising benefit of omega-3s has been found in pregnant women and their newborns: Pregnant women with asthma who eat fish rich in omega-3s during their pregnancy lower their children's risk of asthma. Not just any fish will do. The study (American Thoracic Society International Conference 5/25/04) discovered that mothers who ate fish sticks during pregnancy doubled the asthma risk in their kids. " Fish sticks are deep-fried, and they contain omega-6 fatty acids, which encourage inflammation of the airways," says study co-author Frank Gilliland, MD, PhD, professor at the Keck School of Medicine at the University of Southern California. "Oily fish [like salmon and trout] contain omega-3 fatty acids, which appear to be anti-inflammatory, and lead to the reduced potential for developing asthma and allergies." The USC investigation showed that when women with asthma ate oil-bearing fish during pregnancy, the risk of asthma for their children dropped more than 70%. The more fish that mom consumed, the less likely her baby was to develop asthma. Unfortunately, the study did not find the same benefit in women without asthma. " A family history of asthma is a very strong risk factor for a child developing asthma," Dr. Gilliland says. "It appears that oily fish interacts with the genes involved in the predisposition to develop asthma, and somehow reduces the risk." Although most of us try to avoid accumulating unsightly fat around our hips, the right kind of fat plays an integral part in the functioning of our bodies and may even keep us alive. Fats don't get much better than that.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=344) Women and Depression!
Date:
June 13, 2005 07:48 PM
Women and Depression by Lisa James Energy Times, March 11, 2004 Just as fog veils a beautiful landscape, so depression veils life itself: rendering existence dark and dreary, narrowing the scope of one's dreams. And women are particularly prone to this lingering sadness. The good news: Depression doesn't have to linger forever. With proper nutrition, lifestyle changes and a revived outlook, you can break through that fog into a sunnier emotional clime. Women are more likely than men to fall prey to depression throughout their lifetimes, with women being twice as likely as men to experience major depression. While the greatest risk for both sexes falls at midlife, the gender difference appears early; one in ten teenage girls was found to suffer from major depression in one study (International Journal of Behavioral Development 2004; 28:16-25). What's more, childhood depression leaves a person more susceptible to mood problems in adulthood. One reason for the gender difference in depression, according to researchers, is that women tend to dwell on depressed feelings to a greater degree than men. Some scientists believe a family history of depression carries greater weight for women. Others theorize that the inner fluctuations of a woman's monthly cycle can leave her susceptible to stresses emanating from the outer world. Studies indicate that almost three-quarters of all premenstrual women experience some level of mood difficulties (Summit on Women and Depression, APA, April 02), and a woman's hormonal ebb and flow may even make her more vulnerable to seasonal affective disorder (SAD), the kind of depression linked to a lack of natural light. Warning Signs Not surprisingly, many depressed folks feel sad and lethargic, down on themselves and the world. But in some people, depression is marked by agitation and concentration difficulties, or is accompanied by anxiety. Sleep disturbances-either insomnia or excessive sleepiness-often ensue, and activities that used to provide pleasure lose their appeal. Breaking depression's grip can do more than just lighten your mood-it may help safeguard your health. Studies suggest depression dampens the immune response and may increase the risks of coronary heart disease and diabetes (Archives of General Psychiatry 2003; 60:1009-14; Circulation 2000; 102:1773; Diabetes Care 2004; 27:129-33). Origins of Depression The reasons some people are pulled down by depression's undertow while others are able to stay afloat emotionally are complex, but researchers believe common factors link them all. One factor that can't be ignored is genetics. "If you are depressed, there is a 25% chance that a first-degree relative-a parent, child or sibling-is also depressed," says Hyla Cass, MD, author of St. John's Wort: Nature's Blues Buster (Avery). Other factors are physical problems and medication side effects. That's why your first step should be a consultation with your health care practitioner (if your moods are especially dark, seek professional assistance as soon as possible). Life's worries and cares also weigh more heavily on some people than on others. " [N]ot only will certain stressors [adverse events] cause depression as a direct response," notes Dr. Cass, "but they may predispose an individual to future episodes of depression." For example, the end of a relationship when you feel you've lost a lover and been humiliated (and been cheated on) raises your risk of depression (Archives of General Psychiatry 2003; 60:789-96). The Depressed Brain When depression hits, brain chemistry shifts. As a result, chemicals known as neurotransmitters, which relay messages between brain cells, go awry. For instance, a neurotransmitter called serotonin-critical to mood control-may decrease, leaving you feeling depressed, anxious, craving certain foods and unable to sleep. Conversely, "high levels of serotonin are associated with emotional and social stability," according to Dr. Cass. She adds that, in addition, sex hormones such as estrogen and testosterone "affect brain cells directly." Lifting the Fog Because the causes of depression are so complex, leaving the darkness behind generally requires opening up several pathways. Part of feeling better simply lies in believing that you can. Researchers have found that depressed people who feel they have a sense of control over their troubles, do, in fact, have a better chance of recovery (General Hospital Psychiatry 2000; 22(4):242-50). Finding a community of like-minded folks bolsters your capacity to deal with mood problems. In some cases, time spent with a therapist can be a valuable aid in figuring out what's bothering you. On the physical side, losing weight can lift your spirits. Among women with severe obesity-itself a depression risk factor-losing weight has led to depression relief (Archives of Internal Medicine 2003; 163:2058-65). Research also indicates that exercise helps brighten dark moods. Nutritional Uplift A change in diet, along with certain supplements, can also help dispel depression. The first step on the road to emotional recovery: eat a lot of fresh, organic fruits and vegetables, and stay away from overly refined foods with high levels of sugar. Omega-3 fatty acids, the kinds found in flax seed and fish, are essential to proper brain function. In several studies, people who took supplemental omega-3s found significant relief from depression. Key amino acids-the basic units of which proteins are built-serve as starting points for the production of mood-lifting neurotransmitters. In one trial, people who took an amino-acid mix that included tyrosine enjoyed better moods and were happier than people who took amino acids without it (Psychopharmacology (Berlin) Sept 4 2003). Along with amino acids, the body needs the right vitamins-especially members of the all-important B family-to create depression-fighting brain chemicals. In one study, people with depression who took vitamin B12 improved their chances of recovery (BMC Psychiatry 2003; 3:17). Another interesting observation: Vitamin B12 and its partners vitamin B6 and folate are essential to keep a protein called homocysteine (known primarily as a cardiovascular hazard) from reaching excessive levels, and people with high homocysteine are twice as likely to be depressed. This has led some researchers to speculate that folate may help keep depression under control (Archives of General Psychiatry 2003; 60:618-26). Herbs that may help beat back the blues include two that help the body deal with stress, eleuthero (Eleutherococcus senticosus) and schisandra (S. chinensis). A new diet, a new outlook: With the help of the right nutrients and the right support, you can break the bonds of depression.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=336) Keeping Your Edge - The state of your outer body reflects the inner you.
Date:
June 12, 2005 05:22 PM
Keeping Your Edge by Carl Lowe Energy Times, December 2, 2003 If you want to keep your mental edge, better keep your physical edge. As your body goes, so goes your brain: The state of your outer body reflects the inner you. A flabby body leads to flabby thinking. Weight gain and toneless muscles on the outside are evidence of an out-of-tune brain and thinking processes as soft around the edges as your stomach. But staying in shape physically can boost your mental powers. As you age, one of the biggest threats to keeping your thoughts sharp is Alzheimer's disease, a progressive brain deterioration (dementia) that destroys your memory and your ability to think. Today, about 4.5 million Americans suffer Alzheimer's disease. Over a lifetime, the average cost per person suffering this disease adds up to a staggering $175,000. Consequently, according to the Alzheimer's Association (www.alz.org), this disease drains approximately a billion dollars a year from the US economy. Thanks to an aging population and the growing girth of Americans, the rate of Alzheimer's threatens to explode into an epidemic over the next two decades. Experts now believe that if you are carrying around too much weight, those extra pounds puts you at a higher risk of losing your thinking abilities. And being seriously overweight greatly expands your chances of developing this debilitating type of dementia. An 18-year study of about 400 people in Sweden, all aged 70 at the beginning of the research, concluded that your chances of suffering dementia significantly increases with every extra pound (Archives for Internal Medicine 7/03). Cholesterol Conquers Minds In addition to the extra risk to your thinking capacity from body fat, having high levels of cholesterol in your blood also threatens your brain's ability to reason. Researchers at Georgetown University Medical Center have found that: * Excess amounts of cholesterol can lead to accumulation of APP, a protein found normally in moderate amounts in both the brain and the heart. * Excess APP linked to cholesterol can, in turn, lead to the development of larger amounts of a substance called amyloid protein. * Pieces of amyloid protein can form plaque on the brain, destroying cells and leading to the development of Alzheimer's disease. "Past research has shown that high cholesterol levels appear to increase APP levels, which in turn leads to increased levels of beta amyloid protein and the risk of accumulation of amyloid beta peptide," says Vassilios Papadopoulos, PhD, professor of cell biology at Georgetown. "Our research showed that high cholesterol levels also increase the rate at which the amyloid beta peptides break off and form the tangles that kill brain cells." Added to that, the Georgetown scientists have demonstrated that high cholesterol seems to cause the body to boost its production of the protein, apolipoprotein E (APOE), a chemical that normally helps take cholesterol out of cells. But when APOE accumulates, this chemical leads to an excess of free cholesterol, which kills nerve cells. "Our study adds to the growing body of evidence implicating high cholesterol as a significant risk factor in Alzheimer's disease, and breaks new ground in showing the damage caused by excessive levels of cholesterol," says Dr. Papadopoulos. Since high blood pressure also increases your risk of developing Alzheimer's disease (BMJ 6/14/01), devoting yourself to a heart-healthy lifestyle (eating plenty of fiber, cutting back on saturated fat in red meat and avoiding trans fats in cookies and cakes) can increase your chances of keeping your wits about you as you move through life. Brain Food As part of that heart-healthy lifestyle that keeps your brain functioning at top capacity, experts recommend regular helpings of omega-3 fatty acids, the type of fats found in fish, flax and hemp. In research that focused on people between the ages of 65 to 94, researchers have found that eating seafood at least once a week drops your risk of Alzheimer's by about 60% compared with folks who forego fish (Archives of Neurology 7/03). Along with fish, the scientists recommended munching more nuts, which are rich in polyunsaturated fatty acids. In the report on the relationship between eating and Alzheimer's, Robert Friedland, MD, of the Case Western Reserve University School of Medicine, noted: "A high antioxidant/low saturated fat diet pattern with a greater amount of fish, chicken, fruits and vegetables and less red meat and dairy products is likely to lower the risk of Alzheimer's disease, as that for heart disease and stroke." Wake Up Your Brain If your thinking has been fuzzy lately, take a nap. Getting enough sleep right after you learn something new helps maintain your learning abilities, according to research at the University of Chicago. In a test of how sleep can help people remember words and language, these researchers taught students to recognize a unique vocabulary spoken by a machine. After the learning session, students were then tested on their new abilities. The scientists found that students trained in the morning tested poorly when tested later the same evening. But when students were trained right before bedtime and then tested the next morning, their test scores soared (Nature 9/9/03). "Sleep has at least two separate effects on learning," according to the researchers. "Sleep consolidates memories, protecting them against subsequent interference or decay. Sleep also appears to 'recover' or restore memories." The concept of this research originated in observations of birds. "We were surprised several years ago to discover that birds apparently 'dream of singing' and this might be important for song learning," says researcher Daniel Margoliash, professor of biology and anatomy at the University of Chicago. While you may not dream of singing like a bird, you may dream of having a sharper intellect. Luckily, the tools for sharpening your mental powers are easy to find and put to good use: Methods for keeping your brain in shape are basically the same techniques effective for keeping your body and heart in shape. Pleasant dreams!
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=310) The Blood Sugar Blues - help lower blood sugar
Date:
June 12, 2005 08:08 AM
The Blood Sugar Blues by Carl Lowe Energy Times, July 10, 2003 The cells in your body run on the sugar they get from blood. Normally, this energy distribution system functions efficiently. When things go awry, however, blood sugar fluctuations can cause serious problems. If your blood sugar stays too high, your pancreas, heart and other organs suffer. But stabilize your blood sugar and you can stabilize your health. Problems linked to too much blood sugar are widespread. Diabetes, in which the body becomes increasingly unable to regulate blood sugar levels, is one of the most serious and widespread conditions. Plus, researchers now know that elevated blood sugar, even if you don't suffer diabetes, elevates your risk of heart disease and pancreatic cancer (JAMA 5/17/00). Researchers at the Northwestern University Medical School have shown that with every bump up in your blood sugar levels, your chances of contracting pancreatic cancer rises significantly. "Because the prevalence of type 2 (adult onset) diabetes and obesity, including childhood obesity, is steadily increasing, identifying a potential causal association between hyperglycemia (high blood sugar) and pancreatic cancer could have important preventive and prognosticative implications for this cancer," notes Susan M. Gapstur, MD, a professor at Northwestern. In other words, measuring your blood sugar can go a long way towards measuring the odds of developing this devastating condition. In the United States, pancreatic cancer is the fifth most deadly cancer. The disease is difficult to discover, and tumors in the pancreas usually remain hidden until the cancer has spread throughout the body. Blood Sugar and Heart Problems A collection of researchers now believes your blood sugar level so closely predicts your heart disease risk that blood sugar may be a more accurate heart disease predictor than cholesterol. According to a study in England (BMJ 2001; 322:15), the higher your blood sugar level, the higher your risk of heart disease and other serious health problems. In particular, a type of blood sugar called glycated hemoglobin may provide an indication of what kind of trouble your heart and arteries may face in the future. Glycated hemoglobin is blood glucose (sugar) that has latched onto your red blood cells. The levels of this type of attached sugar climbs when blood sugar levels consistently stay too high. After a while, this sugar not only sticks to blood cells, it also starts sticking to other tissues, an occurrence that can lead to cardiovascular disease. While about one in twenty people in their late 40s or older has diabetes, experts estimate that almost three out of four have at least some degree of elevated glycated hemoglobin. Higher and Higher Men and postmenopausal women are at highest risk for elevated blood sugar. Your blood sugar also generally increases:
You can lower your risk of forming glycated hemoglobin by taking the antioxidant vitamins C and E and drinking three or four alcoholic drinks a week (American Journal of Clinical Nutrition 2000: 71(5)). In addition, losing weight and exercising also drops your glycated hemoglobin. Helpful Chromium When glucose enters the bloodstream after a meal, it has a variety of possible destinations. It can be picked up by brain cells, which use glucose as their only source of fuel (this explains why low blood sugar can cause headaches, dizziness and shakiness). Glucose also can enter muscles, which can burn either glucose or fat for energy. Or glucose can enter fat cells for storage-not a desirable option for someone who is already overweight. One reason blood sugar may rise to unhealthy levels is a condition called glucose resistance or intolerance, which occurs when insulin, the hormone-like substance that shepherds glucose into the body's cells, can't do its job efficiently. That leads to blood which is too rich in both sugar and insulin. Researchers believe that the element chromium can help the body use insulin more effectively, which, when combined with adequate exercise, allows glucose to more easily enter muscle cells. "In experiments, chromium supplementation has actually been found to improve glucose tolerance in some diabetics and in people with impaired glucose tolerance," says nutrition researcher and teacher Shari Lieberman, PhD, in The Real Vitamin and Mineral Book (Avery/Penguin). In a number of investigations, chromium has not only helped improve glucose tolerance, but it has also decreased circulating insulin, glycated hemoglobin and cholesterol levels (Journal of the American College of Nutrition 1998; 17:548-55). (People with elevated glucose levels often suffer from elevations in cholesterol as well. In the search for ways to improve cholesterol levels, Germany's Commission E, an herbal authority respected around the world, has approved the use of garlic to help support healthy cholesterol.) Ginseng and Blood Sugar American ginseng, an herb known as an adaptogen (which means it helps the body cope with everyday stress) is another tool for controlling blood sugar. Research at St. Michael's Hospital and the University of Toronto shows that taking American ginseng (Panax quinquefolium) about 40 minutes before you eat can reduce your blood sugar (Archives of Internal Medicine 4/9/00). According to Vladimir Vuksan, MD, lead investigator for the research team, these findings may have important implications for the treatment and prevention of diabetes. "Although preliminary, these findings are encouraging and indicate that American ginseng's potential role in diabetes should be taken seriously and investigated further. Controlling after-meal blood sugar levels is recognized as a very important strategy in managing diabetes. It may also be important in the prevention of diabetes in those who have not yet developed the disease," says Dr. Vuksan. Fat vs Sugar Supplemental helpings of the fatty acid conjugated linoleic acid (CLA) have also been shown to control blood sugar and lower your risk of diabetes (Journal of Nutrition 1/03). "In previous work, we found that CLA delayed the onset of diabetes in rats," says Martha Belury, PhD, the senior author of the investigation and an associate professor of human nutrition at Ohio State University. "In (our latest) study, we found that it also helped improve the management of adult-onset diabetes in humans." Dr. Belury's research shows that CLA may help lower levels of leptin, a hormone believed to regulate fat levels. By reducing leptin, CLA may help reduce body fat, which, in turn, may lower the risk of diabetes and high blood sugar. Sweet Workouts A consistent, long-term exercise program is one of the single best ways to convince your body to temper blood sugar levels and lower your risk of developing diabetes (Clinical Exercise Physiology 2/15/02). "It now appears that there is...a long-term beneficial effect from regular exercise, most likely due to the fact that a significant amount of fat is lost," says exercise physiologist Cris Slentz, PhD. "Long-term exercise leads to loss of fat in the gut (stomach) region, which is especially beneficial since this fat is thought to be directly linked to increased risk of diabetes and heart disease." Dr, Slentz's study examined how exercise influences the way the body uses sugar in people who have a high risk of diabetes. In this research, five overweight individuals who had never exercised before engaged in an intensive workout program for nine months. Afterwards, they went back to their couch potato lives. Dr. Slentz and other investigators measured their blood sugar before they started the exercise program and then remeasured these levels at one day, five days and thirty days after the nine-month regimen ended. The researchers also looked at these people's insulin sensitivity, a measure of how well their bodies controlled blood sugar. "Insulin sensitivity, or its ability to stimulate glucose metabolism, was higher after nine months of exercise, and the fasting insulin levels were lower," Slentz said. "Just as importantly, 30 days after stopping exercise, insulin sensitivity was still 24% higher than pre-exercise levels, indicating that beneficial effects of exercise persisted." In this study, people pedaled exercise bikes, walked on treadmills and climbed stairs. By the end of the research, they were working out about an hour a day. So if you've put off devoting yourself to an exercise program and taking care of your blood sugar, you now have more reason to start as soon as possible. Paying attention to blood sugar pays off.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=301) Thanks for the Memory
Date:
June 11, 2005 03:49 PM
Thanks for the Memory by Estelle Sobel , February 6, 2002 Thanks for the Memory By Estelle Sobel "I feel like every day, I lose my memory more and more. It started when I couldn't find my car keys, sometimes I forget directions. My mother has Alzheimer's so I'm concerned," says Jerry Solowitz, a 63 year old man. Ellen Lerner, 37, sometimes worries that she can't keep track of everything in her job as a public relations executive. "I feel like stress can get to me easily, and I worry because I forget simple things like where I put a file." Should these people be concerned? "Yes," says Lynda Toth, Ph.D., co-author with Pavel Yutsis, M.D., of Why Can't I Remember? Reversing Memory Loss (Avery, 1999). Jerry should start a specific program with a health practitioner who specializes in memory loss, due to lots of unsuspected new causes for memory dysfunction. Ellen needs to make lifestyle changes, as stress can definitely lead to memory loss. "Cortisol, which is one of the stress hormones, can be harmful because it keeps calcium in the memory pathway too long and destroys the neurons, which is very damaging to the brain," notes Toth. Why Does Memory Fail? Memory fails for several reasons, says Augustine DiGiovanna, M.D., author of Human Aging: Biological Perspectives, (McGraw-Hill 2000), and Professor of Biology at Salisbury State University in Salisbury, MD. Normal Aging: Much of diminished memory as we age is due to reduced blood flow to the brain from atherosclerosis, which is hardening and narrowing of the arteries. Decreased blood flow causes neurons to shrink and function less effectively. Also, as we age we lose neurons and neuron connections that can lead to memory loss. So the way people think, how much they remember, and the mental activities they do determine how many brain cells survive through the years. Finally, as people live longer, the chance is greater that the body's immune system and other defense mechanisms won't be able to protect against certain diseases that affect the brain and memory (Parkinson's, strokes, Alzheimers, atherosclerosis). A Starving Brain: The brain is not getting fed the nutrients it needs (vitamins, minerals, amino acids, glucose). Without the right "food" the brain's energy levels become lowered and stop powering the memory cells. Then, free radicals can do more dirty work and continue to rust memory cells. Drink And Sink: Alcohol passes through the blood-brain barrier and slows down the processing of information between memory neurons. Memory loss increases over time, as memory tissues shrink. Sad Stories: Depression can imbalance the neurotransmitters and electrical charges of neurons. Tense and Tight: High blood pressure can constrict and narrow blood vessels, limiting blood and oxygen flow to the brain. Memory-Sustaining Supplements One way to boost brain power is to take the right supplements. Ginkgo biloba: The powerful medicinal herb ginkgo biloba increases blood flow and circulation to the head by dilating blood vessels in the brain, allowing more oxygenated blood to get to the neurons. It also protects against free radical damage. Research: Ginkgo biloba extract displayed a significant effect on helping the mental abilities of people 50-59 years old (Phytotherapy Research 13, 1999: 408-415). Pregnenolone: This powerful hormone regulates the balance between excitation and inhibition in the nervous system and helps enhance memory and brain function, possibly by repairing a fatty substance that is part of the myelin sheath that surrounds nerve cells. Research: A St. Louis University School of Medicine study on mice showed that pregnenolone enhanced memory and helped mice to navigate mazes better. Huperzine A: This herbal supplement is derived from club moss found in China; in purified form it inhibits the enzyme that breaks down acetylcholine, a neurotransmitter produced in the brain that you need for memory. Research: Studies conducted by Alan Mazurek, M.D., found that huperzine A in purified form improves memory, enhances focus and concentration and has been used to improve memory loss in Alzheimer's patients (Alt. Ther. in Health Med. 5 [2], March 1999: 97-98). Another study in The Journal of Neuroscience Research showed that huperzine A is a potent inhibitor of cholinesterase, which penetrates the brain and produces a dose-dependent increase of the neurotransmitters acetylcholine, norepinephrine and dopamine in rat cortex (41, 1995: 828-835). Phosphatidylserine (PS): This substance, which occurs naturally in nerve cell membranes, helps keep fatty substances soluble and cell membranes fluid and helps reduce levels of cortisone which are damaging to tissues. Research: Phosphatidylserine encourages a sense of calm by raising the levels of alpha brain waves and increasing the production of acetylcholine (Neuropsychobiology 24, 1990-1991: 42-48). Vitamin E: This potent antioxidant attaches to bad cholesterol and helps prevent free radical damage to cells. Research: Age-related processes like memory function and problem solving can be affected by free radical damage. Several studies show that vitamin E might slow the effects of Parkinson's disease and Alzheimer's disease (JAMA 282, August 18, 1999: 621). Acetyl-l-carnitine: Increases cognitive performance because it rejuvenates cellular membranes of mitochondria, the storehouses of energy contained in every living cell. Alpha-Lipoic Acid: Preserves memory tissue by increasing glutathione levels, which protect fat stores in neurons from being damaged. Nine Ways to Remember Dr. Lynda Toth suggests the following ways to make the most of what you've now got. 1) Power Up Your Smile. Remove dental fillings and replace them with porcelain or ceramic ones. The mercury in metal fillings may be harmful (some believe) and can affect the brain and nervous system, inflaming memory tissue and preventing the entry of nutrients into the cells. 2) Don't Be a Tin Man/Woman Avoid exposure to aluminum. Don't use aluminum pots to cook in. Aluminum accumulates in memory tissue, damaging cells. In fact, autopsies of Alzheimers patients show they have unusually huge amounts of aluminum in the brain. But no one knows where this aluminum comes from. 3) Eat Right. Eat organic and pesticide-free foods. Pesticides get into the cells and can damage DNA. 4) A Matter of Taste. Avoid foods with artificial coloring, monosodium glutamate (MSG, often called "natural flavors" or "natural seasoning"). Also avoid processed foods with taste enhancers called exito toxins such as l-cysteine and aspartic acid. 5) In the Raw. Make sure that your diet consists of enzyme-rich 50% raw foods (fruits and vegetables) to feed the brain. Eat less animal fats. * Drink green juices to support levels of the brain's clean-up enzymes. *Eat lots of fiber, which helps remove toxins from the body. Pick up psyllium fiber. *Limit intake of processed sugar, caffeine and alcohol to lessen the load on the liver and pancreas. 6) Cut Bait. Watch the fish that you eat. Lots of ocean and inland-caught fish are contaminated with mercury. Go for deep, cold water fish such as cod. Avoid shark and swordfish. 7). Oil Up. Supplement your diet with omega-3 fatty acids, such as cod liver oil or flaxseed oil. These fats lubricate memory cells. 8) Work That Body. Stay fit and exercise. Exercise helps oxygenate the body, reduces cholesterol, and builds and energizes new memory cells which reduces wear and tear on the brain function. 9) Do Mind Games. Read, listen to music. Tune into different radio stations than the ones you normally listen to. Do crossword puzzles and a wide selection of word games which can stretch your brain and give it a tough workout. Student of Life You need to keep learning your whole life to keep your brain and memory in tip top shape. The brain is adaptable, and you are always building new neurons, says Dr. Toth, which means that there is no limit to how long it can develop. Anything that stimulates the brain will help it to grow. That's why as you get older it's even more important to take classes, start a new hobby, travel. In fact, the challenge of learning and doing new things (without stopping in a fit of frustration) causes your brain to grow, says Dr. Mazurek. The Good News As people get older, their brains may actually improve and repair themselves through a complicated process that is designed to eliminate faulty neurons that are prone to making mistakes. At the same time, brain activity goes on that results in the development of new and improved connections with neighboring neurons. Research also shows that memory improves if you train people to have faith in themselves. (The brain helps those who help themselves.) Apparently, a confident perspective can encourage the brain to actually improve to the point where its new-found abilities may increase to the point where it fulfills expectations. So keep your chin up and stay away from the artery-clogging saturated fat that can cut off the brain's blood supply. It's all in the attitude, says Dr. DiGiovanna. And, of course, the key to a long and happy life with your brain is also on the end of your fork and in that bottle of supplements. Estelle Sobel, is the co-author of Beautiful Skin: Every Woman's Guide to Looking Her Best at Any Age (Adams Media, May 2000).
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=289) Improove Memory ...
Date:
June 09, 2005 05:49 PM
Mesmerizing Memory by Cal Orey Energy Times, January 1, 1999 In the 60s, the same rock 'n' rollers who belted out "One pill makes you larger and one pill makes you small," often espoused the belief that certain pills could expand the mind. While counter-culture pill purveyors were pilloried for their pill-popping claims, 90s nutritional research has uncovered a stash of supplements that may amplify mental improvement. Like a blues singer bending a high note, researchers are now humming with dramatic assertions that certain nutritional supplements can sustain and enhance concentration and memory function. For instance, studies reveal possible benefits for cognitive powers from vitamin C, magnesium and Ginkgo biloba. A recent report in the Journal of the American Medical Association (JAMA 278:1327-1332) said that an extract of Ginkgo biloba "can stabilize and, in some cases, improve the cognitive function and social behavior of demented patients." A researcher in the Proceedings of the National Academy of Sciences noted that a daily dose of vitamin E may "help protect the brain and its memories from the ravages of time." And the beat goes on: other evidence indicates that zinc, iron and boron may pump up short-term memory attention span and cut the time it takes to perform mental tasks.
Neuronutrients Lester Packer, PhD, professor of molecular and cell biology at UC Berkeley, told a joint 1996 United Nations-World Health Organization conference on Aging that "there is a growing body of evidence indicating that the free radical theory of aging and aging-related disease is valid," and that dietary and supplemental antioxidants can help fight illness and mental deterioration. Vitamin E and other memory aids are believed to protect brain chemicals called neurotransmitters, "the ferrymen of the brain's communication system," that influence concentration and memory. Experts say that sustaining the level of these nerve chemicals in the brain can potentially improve all mental processes.
Brain Well-Being Too much alcohol, for example, commonly causes progressive mental decline, according to Secrets of the Superyoung (Villard) by David Weeks and Jamie James. The authors also point out that "the memory tends to worsen noticeably after 15 years of alcohol drinking, and much sooner in people who go on massive binges." "The effects of cigarette smoke are subtler because the poisonous effects of carbon monoxide in each puff are temporarily offset by the alerting effects of the nicotine," they add. Can't remember the name of that singer cavorting in a music video? Tests have shown that smokers are worse at connecting peoples' names to their faces than nonsmokers.
Cognition Ignition n Learn something new: A second language, musical instrument, or unique puzzles and games keep neurons working like new. n Turn off the TV: Read. Studies show that passively watching TV requires less concentration than eating cereal. Mental rejuvenation also requires physical activity. Exercise increases oxygen flow to the brain, which supports memory, concentration and cognition. One study has shown that exercise significantly brightened the moods of middle-aged and older women, regardless of whether they were pre- or post-menopausal, with or without hormone replacement therapy.
Supplemental Brain Help Antioxidants, including the previously mentioned vitamin E (You haven't forgotten vitamin E already, have you?), provide crucial help for vigorous cerebral function. The free radicals created by tobacco smoke, air pollution, ultraviolet light and certain carcinogenic chemicals deconstruct cell membranes and may foster microscopic brain cell havoc. Antioxidant enzymes convert free radicals to more neutral, benign substances and nutritional antioxidants can neutralize free radicals by linking up with them. Vitamin C, a brainy antioxidant all star, performs so well that, according to Dr. Khalsa, its levels in the brain are almost 15 times higher than in other parts of the body. This nutrient, he asserts, aids mental and physical longevity. In a UCLA study, people who ingested at least 300 mg of vitamin C daily lived more than six years longer than those who ingested less.
Mental Fat Added to this mix, magnesium also scavenges free-radicals, according to Dr. Khalsa. Plus, experts recommend grape seed extract (phytochemicals that protect a wide range of cellular structures) to safeguard nerve cells and mental capacity.
B Vitamins for the Mind
Iron Mind Boron plays a crucial part in mental function. Scientists at the USDA's Human Nutrition Research Center have linked boron deficiencies to chronic lethargy and fatigue. In brain studies, they found that the electrical activity of the gray matter in the boron deficient indicated increased drowsiness and mental sluggishness.
Huperzine Boost HupA basically protects the brain from free radical damage (due to low levels of antioxidant defenses) and maintains or enhances crucial neurotransmitter action. More specifically, HupA helps reduce the breakdown of acetylcholine, the vital neurotransmitter, and makes this substance more bioavailable. In addition, HupA helps make choline accessible to the brain for the synthesis of acetylcholine, according to a study in Neuropharmacology (30, 1991: 763-768). Normally, the brain manufactures sufficient levels of the chemical phosphatidylserine, a lecithin-derivative that helps boost neurotransmitter release, but deficiencies of vitamin B12 and folic acid, or of essential fatty acids, may retard that production. Low levels of phosphatidylserine in the brain are related to impaired mental function and depression in the elderly. Scientists reporting in Aging (5, 1993; 123-33) describe "good results" using phosphatidylserine in the treatment of age-related cognitive ills.
Ginkgo Brain Power Another ingredient in what seems like an alphabet-soup of brain nourishment is DHA (docosahexaenoic acid), an omega-3 fat essential for normal brain function. Researchers met recently at The New York Hospital-Cornell Medical Center's Nutrition Information Center to discuss "Keeping Your Brain in Shape: New Insights into DHA." Their findings revealed links between low levels of DHA and Alzheimer's, depression, memory loss, attention-deficit/hyperactivity disorder (ADHD) and certain behavioral traits including aggression and hostility.
Mostly Fat Researchers from the National Institutes of Health point out, however, that fish is an excellent dietary source of DHA. In their studies, they discovered that depression rates in Japan and Taiwan, where fish ranks a top spot on the menu, are significantly lower than in North America and Europe. DHA also is crucial to the neurological development of children, according to findings published in Pediatrics (vol. 101, no. 1, January 1998). Researchers suggest that DHA-rich breast milk should be the model for infant formulas that enhance babies' neurological development. Scientists also have correlated some behavioral problems in children-ADHD, for example-to DHA deficiencies. If you are a vegetarian, or have other cause for concern about a potential lack of DHA in your diet, you can rely on dietary supplementation of DHA. Bruce J. Holub, PhD, of the University of Guelph in Canada provided vegetarians in his research project with DHA supplements over a 42-day period and substantially increased their DHA blood levels. The bottom line to enhanced mental performance is to take a balanced approach, says Robert Snider, MD, who specializes in preventive medicine in Massena, New York. "Maintaining brain power includes exercise, stress reduction and good nutrition." The message to keep in mind: Don't lose your nutritional balance or you could lose a piece of your peace of mind. Recommended Reading: & Brain Builders (Reward Books, 1995), by Richard Leviton. Brain Longevity (Warner Books, 1997), by Dharma Singh Khalsa, MD. Omega 3 Oils to Improve Mental Health, Fight Degenerative Diseases and Extend Life (Avery, 1996), by Donald Rudin, MD, and Clara Felix. Successful Aging (Pantheon, 1998), by John W. Rowe, MD, and Robert L. Kahn, PhD.
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=261) Pycnogenol Complex - The Next Generation of Antioxidant Protection
Date:
June 04, 2005 02:14 PM
If there’s one factor that has the greatest negative impact on our health, it is the damage done to our cells by free radicals. These highly unstable molecules disrupt the biochemical processes that regulate life. Although a natural product of oxygen metabolism in the body, free radicals are also produced in vast quantities by modern technology. Our bodies’ natural defenses simply have not been able to keep up with the onslaught of these dangerous products of civilization. On the other hand, technology has offered help by identifying some of nature’s most powerful weapons against free radical attack. Source Naturals PYCNOGENOL® COMPLEX is an unprecedented combination of these extremely potent plantbased antioxidants, or Plantioxidants™. Consider them your antidote to the industrial revolution. How free radicals are formed and their effect on the body Oxygen both makes life, and takes life. The energy that animates us comes from the biochemical reactions that burn oxygen within our cells. And though carefully regulated by the body, this biological combustion, over time, inevitably leads to cellular damage. If oxidation is not carefully controlled, tissues are damaged faster than the body can repair them. This is caused by an excess of over-reactive, electron hungry molecules called oxidants or “free radicals,” which tend to disrupt normal cellular activity. Free radicals attack a cell’s membrane and can even damage its hereditary blueprint (DNA). Since free radicals are a natural result of certain metabolic reactions, the body synthesizes several types of antioxidant enzymes to neutralize them. In addition, we get essential antioxidants from the foods we eat. Vitamins C, E and beta carotene are the ones found most often in our diet. During this century, our environment has become a perpetual source of free radical contamination, primarily from radiation and the chemical pollution in our air, water and food. Today, we are literally overwhelmed with more free radicals than our bodies are accustomed to handling. Fortunately, science has found that certain plants contain special antioxidants that are far more powerful than the vitamins we typically get in our diet. With this knowledge, Source Naturals formulated PYCNOGENOL® COMPLEX, the most advanced combination of Plantioxidants available today in one product. Pycnogenol® is the proprietary name of a natural plant product made from the bark of the European coastal pine, Pinus maritima. Natural protection against free radicals Pycnogenol® Complex – A Cornucopia of Health Our knowledge of pine bark goes back nearly 500 years, to when the French explorer, Jacques Cartier, reported that a tea made from pine tree bark by Native Americans saved the lives of his crew who were dying of scurvy. Nutrition scientists have since isolated the extraordinary antioxidant compounds of pine bark. They have also discovered many other unique antioxidants throughout the plant kingdom. Plants have evolved bioflavonoids to protect themselves from free radical damage. One of the most abundant compounds in the plant kingdom, bioflavonoids are found in the pigments of bark, rinds, seeds, leaves and flowers. Natural antioxidants in Pycnogenol® Complex The active ingredients of Source Naturals PYCNOGENOL® COMPLEX are derived from a diverse range of nature’s plenty: pine bark, green tea, turmeric spice, rosemary, grape seeds, milk thistle seeds, bilberries, hawthorn berries and ginkgo leaves. Each of these Plantioxidants is an exceptional free radical scavenger, and each has a tendency to concentrate in a different organ of the body, thus providing targeted protection. And since their primary function is to capture free radicals, these Plantioxidants free up vitamin C, so it can perform its many other vital functions. Defense Plants The two headliners of Source Naturals PYCNOGENOL® COMPLEX are the pine bark extract, Pycnogenol®, and an extract from grape seeds, Proanthodyn™. Their unsurpassed antioxidant activity – up to 20 times that of Vitamin C and up to 50 times that of Vitamin E – comes from a high concentration of proanthocyanidins. Why Pycnogenol® Complex is formulated with extracts of pine bark and grape seed These highly bioavailable flavonoids are able to cross the Blood-Brain Barrier, and can stay in the bloodstream for up to 72 hours. Few other nutritional antioxidants cross this barrier, and none do it as well. Proanthocyanidins therefore offer the brain and central nervous system unparalleled antioxidant protection. In particular, proanthocyanidins may help reduce the formation of lipofuscin, a brown waste material made of free radical-damaged proteins and fats. Over time, lipofuscin deposits form in the brain, heart, and skin. The “age” or “liver” spots that develop on the backs of some elderly peoples’ hands are made of lipofuscin. Because they’re rich in unsaturated fatty acids, cell membranes are the primary site of free radical attack. Proanthocyanidins are able to protect against both water- and fat-soluble free radicals. Also, their chemical structure is incorporated within cell membranes, making proanthocyanidins very effective in preventing damage to the cell’s interior. This is vital, because if a cell’s DNA is disrupted, it could lead to the abnormal reproduction of that cell. For many years now, Europeans have used pine bark and grape seed extracts to maintain vein and capillary health. Proanthocyanidins support the circulatory system by helping to keep collagen and elastin, the essential constituents of vessel walls, from breaking down during times of imbalance. And most importantly, proanthocyanidins can help prevent the oxidation of LDL cholesterol in the bloodstream. Scientists now recognize that it’s not cholesterol itself, but the oxidation of cholesterol that can be problematic. How Plantioxidants benefit different organs in the body The Power of Diversity In addition to the broad protection offered by Pycnogenol® and Proanthodyn, Source Naturals PYCNOGENOL® COMPLEX offers an outstanding array of other Plantioxidants. Each has unique abilities to protect the body from oxidants. For several thousand years, Green Tea has been enjoyed in the Orient, not only for its taste, but also as a health tonic. Upon analysis, it contains several strong antioxidants, called Polyphenols, with exceptional free radical scavenging abilities. Polyphenols have been shown to be over 200 times more effective than vitamin E in preventing oxidative damage to brain cells. Source Naturals uses a potent extract of green tea that concentrates 2,000 pounds of fresh green tea leaves into one pound of finished product. This extract has been awarded 30 patents for its protective effects. The ancient Ginkgo Biloba tree has long been prized for its beneficial qualities. Like proanthocyanidins, ginkgo’s compounds are able to cross the Blood-Brain Barrier, and support cell membrane and capillary integrity. Its particular antioxidant constituents have been associated with superior oxygen transport to the brain. This is important because the brain uses 20% of all inhaled oxygen. Source Naturals PYCNOGENOL® COMPLEX uses a superior 50 to 1 extract, providing 24% Ginkgoflavoneglycosides and 6% Terpenoids. Bilberries were first studied for their capacity to heighten visual acuity in normal subjects under poor light conditions. In fact, to increase their night vision, RAF pilots ate bilberry jam during WW II. Its antioxidant compounds, Anthocyanosides, have an affinity for delicate eye tissues, where it quenches free radicals and supports capillary strength. Source Naturals utilizes a standardized bilberry extract with 25% anthocyanosides, 80 times more potent than regular bilberry. The wide range of natural antioxidants in Source Naturals PYCNOGENOL® COMPLEX Milk Thistle Seed Extract has been researched and used for over 20 years in Europe. Its antioxidant compound, called Silymarin, has a special preference for the liver. It’s one of the few nutrients that can support the liver’s natural regenerative processes. By enhancing DNA activity, liver cells can regenerate up to five times faster. Turmeric Extract contains 95% Curcumin, the active ingredient of this traditional East Indian spice. Curcumin promotes the body’s own production of antioxidant enzymes, including glutathione peroxidase, an important protector of the liver. Curcumin also increases the production and secretion of bile, which is used to remove cholesterol from the body. Quercetin has been well-researched for its free radical scavenging activity. Because of its ability to stabilize cell membranes, quercetin helps prevent damage and discomfort from reactionary (histamine- and leukotriene-related) processes in the body. Source Naturals quercetin has been isolated from plant sources. Rosemary and Hawthorn Berries both contain bioflavonoid antioxidants that have the unique ability to neutralize the hydroxyl radical, a particularly dangerous type of free radical. Hydroxyls are produced by exposure to excessive radiation and pollution from burned fossil fuels. The body has no innate defense system against it. Vitamin C is one of the most active and abundant antioxidants in the body, so it must be frequently replenished. Since it works in conjunction with bioflavonoids, each tablet of Source Naturals PYCNOGENOL® COMPLEX contains 500 mg of vitamin C, bound to Magnesium for increased bioavailability. A World of Help As we better understand how free radicals affect our health and well being, it’s important that we take advantage of the wonderful protective qualities found in certain plants. These Plantioxidants provide the appropriate means to counteract the destructive effects of excessive free radicals, which have become part and parcel of modern life. Source Naturals PYCNOGENOL® COMPLEX brings the diverse and concentrated power of the plant world into your world of wellness.
References
(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=189) PREGNENOLONE - The Balancing Hormone
Date:
June 04, 2005 01:40 PM
Hormones are potent regulators of the most intricate biochemical functions involved in our metabolism, growth, development, emotion and behavior. For our bodies to function properly, our hormones must be in balance with one another. But aging, stress and environmental factors can contribute to hormonal imbalances, with serious impact on our well-being. Today, science has rediscovered a beneficial hormone with the capacity to reduce stress, fatigue and support mental alertness. This hormone is broad – spectrum in its influences - with the ability to balance the levels of other hormones in our bodies. Unfortunately, our production of this hormone declines as we grow older - suggesting the desirability of supplementation. Introducing: Source Naturals PREGNENOLONE. A Wide Range of Beneficial Properties Pregnenolone - a hormone produced from cholesterol in our adrenal glands, liver, skin, testicles, ovaries, and brain - was the subject of intense interest in the 1940’s. Some of the earliest studies, performed by well-known researcher Hans Selye, found it to be helpful in reducing stress and fatigue. Additional studies were conducted throughout the decade, with positive results. Pregnenolone supplementation was found to benefit people who were under excessive stress. It also was reported to support joint and tissue function and to contribute to skin elasticity. Pregnenolone is believed to affect stress levels through its influence on the adrenal glands, which produce more steroid hormones when people are under stress. Pregnenolone may also affect brain chemistry in beneficial ways. It has been found to inhibit the GABA receptors in brain cells - which may result in increased mental alertness. It may also stimulate the NMDA (N-methyl-D-aspartate) receptors, which play an important role in regulating synapses, thus influencing learning and memory. Pregnenolone: The Unique Hormone Much of the current interest in pregnenolone is related to its role as “the grandmother of all steroid hormones.” Pregnenolone is the starting point from which all steroid hormones are manufactured in our bodies. As a “hormone balancer,” it has the capacity to increase the levels of steroid hormones that are deficient in our bodies and to reduce the levels of excess circulating hormones. Some scientists believe pregnenolone is converted into other hormones only as they are needed by our bodies. The conversion of pregnenolone follows different pathways, depending upon cellular requirements. Pregnenolone may be converted into DHEA (dehydroepiandrosterone), which in turn can be changed into androgens (including testosterone), estrogens and other steroids; or, it may be converted into any or all of a chain of hormones including progesterone, corticosterone, and aldosterone. These characteristics make pregnenolone unique. Because cells may only convert pregnenolone into other hormones on an “as needed” basis, pregnenolone may correct imbalances in the levels of some hormones, without affecting others. This is a great advantage over steroid hormones like DHEA, which may create excess estrogen and testosterone. Pregnenolone is also distinctive because of the innumerable bodily activities it can influence. As a steroid hormone precursor, it is believed to be involved in every biochemical action exhibited by any steroid hormone. This means it may impact memory, mental alertness, stress responses, female reproductive cycles, the body’s natural defenses, and joint and tissue function. With such a wide spectrum of involvement, the potential uses of pregnenolone could be boundless. Source Naturals PREGNENOLONE is available in 10 mg sublinguals and tablets, as well as in 25 mg tablets. All potencies are sold in 60 and 120 tablet bottles.
References
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